A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a study to demonstrate the effect of oral ozanimod as maintenance therapy in participants with moderately to severely active Crohn's Disease.

Study Overview

• Status: Terminated
• Conditions: Crohn Disease
• Intervention / Treatment: Other: Placebo; Drug: Ozanimod

• Study Type: Interventional
• Enrollment (Actual): 550
• Phase: Phase 3

Contacts and Locations

Study Locations

• Argentina
  • Buenos Aires, Argentina
    • Local Institution - 501
  • Buenos Aires, Argentina, 1702
    • Local Institution - 571
  • Buenos Aires, Argentina, B1878
    • Local Institution - 500
  • Buenos Aires, Argentina, 1180
    • Local Institution - 494
  • Córdoba, Argentina, X5003DCE
    • Local Institution - 570
  • Córdoba, Argentina, X5016
    • Local Institution - 495
  • Mar del Plata, Argentina, B7600
    • Local Institution - 569
  • Rosario, Argentina, 2000
    • Local Institution - 496
  • Rosario, Argentina, 2000
    • Local Institution - 497
  • Rosario, Santa Fe, Argentina, S2002
    • Local Institution - 502
  • San Miguel de Tucumán, Argentina, 4000
    • Local Institution - 492
• Australia
  • Bankstown, Australia, 2200
    • Local Institution - 325
  • Box Hill, Australia, 3128
    • Local Institution - 330
  • Sydney, NSW, Australia, NSW 2050
    • Local Institution - 324
  • New South Wales
    • Concord, New South Wales, Australia, 2139
      • Local Institution - 310
    • Kingswood, New South Wales, Australia, 2747
      • Local Institution - 319
    • Liverpool, New South Wales, Australia, 2170
      • Local Institution - 309
    • New Lambton Heights, New South Wales, Australia, 2305
      • Local Institution - 318
    • Wollongong, New South Wales, Australia, 2500
      • Local Institution - 323
  • Queensland
    • Herston, Queensland, Australia, 4029
      • Local Institution - 328
    • Maroochydore, Queensland, Australia, 4558
      • Local Institution - 707
    • Maroorchydore, Queensland, Australia, 4558
      • Local Institution - 313
    • North Mackay, Queensland, Australia, 4740
      • Local Institution - 321
    • South Brisbane, Queensland, Australia, 4101
      • Local Institution - 312
    • Woolloongabba, Queensland, Australia, 4102
      • Local Institution - 311
  • South Australia
    • Adelaide, South Australia, Australia, 5000
      • Local Institution - 308
    • Adelaide, South Australia, Australia, 5112
      • Local Institution - 708
    • Bedford Park, South Australia, Australia, 5042
      • Local Institution - 307
    • Elizabeth Vale, South Australia, Australia, 05112
      • Local Institution - 326
    • Woodville South, South Australia, Australia, 5011
      • Local Institution - 320
  • Victoria
    • Clayton, Victoria, Australia, 3168
      • Local Institution - 317
    • Fitzroy, Victoria, Australia, 3065
      • Local Institution - 305
    • Geelong, Victoria, Australia, 3220
      • Local Institution - 329
    • Melbourne, Victoria, Australia, 3004
      • Local Institution - 327
    • Melbourne, Victoria, Australia, 3004
      • Local Institution - 709
  • Western Australia
    • Murdoch, Western Australia, Australia, 6150
      • Local Institution - 316
    • Subiaco, Western Australia, Australia, 6008
      • Local Institution - 315
• Austria
  • Innsbruck, Austria, 6020
    • Local Institution - 726
  • Sankt Pölten, Austria, 3100
    • Local Institution - 727
  • Vienna, Austria, 1020
    • Local Institution - 336
  • Vienna, Austria, 1090
    • Local Institution - 725
• Belarus
  • Grodno, Belarus, 230026
    • Local Institution - 745
  • Vitebsk, Belarus, 210604
    • Local Institution - 737
• Belgium
  • Brussels, Belgium, 1090
    • Local Institution - 940
  • Edegem, Belgium, 2650
    • Local Institution - 939
  • Ghent, Belgium, 9000
    • Local Institution - 937
  • Leuven, Belgium, 3000
    • Local Institution - 942
  • Liège, Belgium, 4000
    • Local Institution - 936
  • Seraing, Belgium, 4100
    • Local Institution - 938
  • Tournai, Belgium, 7500
    • Local Institution - 941
  • Antwerpen
    • Brasschaat, Antwerpen, Belgium, 2930
      • Local Institution - 943
• Bosnia and Herzegovina
  • Banja Luka, Bosnia and Herzegovina, 78000
    • Local Institution - 743
  • Mostar, Bosnia and Herzegovina, 88000
    • Local Institution - 741
  • Sarajevo, Bosnia and Herzegovina, 71000
    • Local Institution - 738
  • Sarajevo, Bosnia and Herzegovina, 71000
    • Local Institution - 742
• Bulgaria
  • Blagoevgrad, Bulgaria, 2700
    • Local Institution - 456
  • Plovdiv, Bulgaria, 4002
    • Local Institution - 746
  • Rousse, Bulgaria, 7002
    • Local Institution - 753
  • Sofia, Bulgaria, 1407
    • Local Institution - 750
  • Sofia, Bulgaria, 1407
    • Local Institution - 755
  • Sofia, Bulgaria, 1431
    • Local Institution - 756
  • Sofia, Bulgaria, 1527
    • Local Institution - 752
  • Sofia, Bulgaria, 1784
    • Local Institution - 554
  • Sofia, Bulgaria, 1202
    • Local Institution - 747
  • Sofia, Bulgaria, 1527
    • Local Institution - 627
  • Sofia, Bulgaria, 1606
    • Local Institution - 749
  • Sofia, Bulgaria, 1784
    • Local Institution - 748
  • Stara Zagora, Bulgaria, 6000
    • Local Institution - 553
  • Varna, Bulgaria, 9002
    • Local Institution - 754
• Canada
  • Alberta
    • Calgary, Alberta, Canada, T2N 4Z6
      • Local Institution - 273
    • Edmonton, Alberta, Canada, T5R1W2
      • Local Institution - 269
    • Edmonton, Alberta, Canada, T5R 1W2
      • Local Institution - 227
  • British Columbia
    • Kelowna, British Columbia, Canada, V1Y 1Z9
      • Local Institution - 263
    • New Westminster, British Columbia, Canada, V3L 3W5
      • Local Institution - 262
    • Vancouver, British Columbia, Canada, V6Z 2K5
      • Local Institution - 267
    • Vancouver, British Columbia, Canada, V5Z1M9
      • Local Institution - 255
  • Manitoba
    • Brandon, Manitoba, Canada, R7A 0N7
      • Local Institution - 256
    • Winnipeg, Manitoba, Canada, R3CON2
      • Local Institution - 261
  • Nova Scotia
    • Bridgewater, Nova Scotia, Canada, B4V 3N2
      • Local Institution - 268
  • Ontario
    • Greater Sudbury, Ontario, Canada, P3C 5K6
      • Local Institution - 266
    • London, Ontario, Canada, N6A 5A5
      • Local Institution - 252
    • London, Ontario, Canada, N6A 5W9
      • Local Institution - 251
    • Toronto, Ontario, Canada, M5G 1X5
      • Local Institution - 264
    • Toronto, Ontario, Canada, M5T 3A9
      • Local Institution - 257
    • Vaughan, Ontario, Canada, L4L 4Y7
      • Local Institution - 271
  • Quebec
    • Montreal, Quebec, Canada, H1T 2M4
      • Local Institution - 254
    • Ottawa, Quebec, Canada, K1H 8L6
      • Local Institution - 270
• Chile
  • Concepción, Chile, 4070038
    • Local Institution - 389
  • Santiago, Chile, 7500010
    • Local Institution - 392
  • Santiago, Chile, 7500571
    • Local Institution - 387
  • Santiago, Chile, 7550000
    • Local Institution - 391
  • Santiago, Chile, 8320000
    • Local Institution - 390
• China
  • Beijing, China, 100050
    • Local Institution - 482
  • Beijing, China, 100700
    • Local Institution - 467
  • Bengbu, China, 233004
    • Local Institution - 379
  • Changchun, China, 130021
    • Local Institution - 485
  • Changchun, China, 130033
    • Local Institution - 376
  • Changsha, China, 410008
    • Local Institution - 421
  • Changsha, China, 450052
    • Local Institution - 378
  • Changzhou, China, 213004
    • Local Institution - 414
  • Fuzhou, China, 350005
    • Local Institution - 422
  • Guangzhou, China, 510030
    • Local Institution - 478
  • Guangzhou, China, 510180
    • Local Institution - 472
  • Guangzhou, China, 510655
    • Local Institution - 486
  • Hangzhou, Zhejiang, China, 100142
    • Local Institution - 470
  • Hefei, China, 230001
    • Local Institution - 491
  • Kunming, China, 650032
    • Local Institution - 374
  • Luzhou, China, 646099
    • Local Institution - 383
  • Nanchang, China, 330006
    • Local Institution - 488
  • Nanjing, China, 210009
    • Local Institution - 375
  • Nanjing, China, 210029
    • Local Institution - 487
  • Nanjing, China, 210008
    • Local Institution - 418
  • Shanghai, China, 200025
    • Local Institution - 473
  • Shanghai, China, 200040
    • Local Institution - 380
  • Shanghai, China, 200080
    • Local Institution - 377
  • Shanghai, China, 200092
    • Local Institution - 416
  • Taichung City, China, 40447
    • Local Institution - 458
  • Tianjin, China, 300052
    • Local Institution - 373
  • Wuhan, China, 430022
    • Local Institution - 475
  • Wuhan, China, 430030
    • Local Institution - 474
  • Wuhan, China, 430060
    • Local Institution - 483
  • Wuxi, China, 214023
    • Local Institution - 381
  • Xi'an, China, 710038
    • Local Institution - 415
  • Xi'an, China, 710100
    • Local Institution - 420
  • Zhengzhou, China, 450014
    • Local Institution - 370
  • Jiangsu
    • Changzhou, Jiangsu, China, 213003
      • Local Institution - 423
  • Shanghai Municipality
    • Shanghai, Shanghai Municipality, China, 200120
      • Local Institution - 369
  • Sichuan
    • Chengdu, Sichuan, China, 610041
      • Local Institution - 419
• Colombia
  • Barranquilla, Colombia, 080020
    • Local Institution - 398
  • Bogotá, Colombia, 110221
    • Local Institution - 395
  • Medellín, Colombia, 050034
    • Local Institution - 394
  • Santiago de Cali, Colombia, 760026
    • Local Institution - 396
  • Quindío Department
    • Armenia, Quindío Department, Colombia, 630004
      • Local Institution - 397
• Croatia
  • Koprivnica, Croatia, 48000
    • Local Institution - 453
  • Osijek, Croatia, 31000
    • Local Institution - 763
  • Split, Croatia, HR-21000
    • Local Institution - 765
  • Zagreb, Croatia, 10000
    • Local Institution - 452
  • Zagreb, Croatia, 10000
    • Local Institution - 762
  • Zagreb, Croatia, 10000
    • Local Institution - 766
• Czechia
  • Brno, Czechia, 615 00
    • Local Institution - 767
  • Brno, Czechia, 656 91
    • Local Institution - 772
  • Hradec Králové, Czechia, 500 12
    • Local Institution - 773
  • Most, Czechia, 43401
    • Local Institution - 775
  • Olomouc, Czechia, 77900
    • Local Institution - 771
  • Pardubice, Czechia, 532 03
    • Local Institution - 774
  • Pilsen, Czechia, 30460
    • Local Institution - 769
  • Prague, Czechia, 120 00
    • Local Institution - 573
  • Prague, Czechia, 14000
    • Local Institution - 368
  • Prague, Czechia, 14021
    • Local Institution - 776
  • Prague, Czechia, 150 06
    • Local Institution - 768
  • Prague, Czechia, 190 00
    • Local Institution - 770
• Denmark
  • Copenhagen, Denmark, 2400
    • Local Institution - 611
  • Holbæk, Denmark, 4300
    • Local Institution - 610
  • Nykøbing Falster, Denmark, 4800
    • Local Institution - 609
• Finland
  • Helsinki, Finland, 00290
    • Local Institution - 613
  • Turku, Finland, FI-20521
    • Local Institution - 614
• France
  • Amiens, France, 80054
    • Local Institution - 638
  • Blois, France, 41016
    • Local Institution - 635
  • Béziers, France, 34525
    • Local Institution - 639
  • Caen, France, 14000
    • Local Institution - 634
  • Colombes, France, 92701
    • Local Institution - 644
  • Créteil, France, 94010
    • Local Institution - 711
  • Dijon, France, 21079
    • Local Institution - 616
  • Grenoble, France, 38700
    • Local Institution - 615
  • Lillie Cedex, France, 59037
    • Local Institution - 633
  • Marseille, France, 13915
    • Local Institution - 646
  • Montpellier, France, 34295
    • Local Institution - 507
  • Nantes, France, 44093
    • Local Institution - 632
  • Pierre-Bénite, France, 69495
    • Local Institution - 630
  • Rennes, France, 35033
    • Local Institution - 641
  • Rouen, France, 76031
    • Local Institution - 612
  • Saint-Priest-en-Jarez, France, 42270
    • Local Institution - 631
  • Toulouse, France, 31059
    • Local Institution - 643
  • Cedex
    • Neuilly-sur-Seine, Cedex, France, 92200
      • Local Institution - 647
• Georgia
  • Batumi, Georgia, 6010
    • Local Institution - 786
  • Kutaisi, Georgia, 4600
    • Local Institution - 779
  • Tbilisi, Georgia, 0101
    • Local Institution - 454
  • Tbilisi, Georgia, 0112
    • Local Institution - 778
  • Tbilisi, Georgia, 0131
    • Local Institution - 782
  • Tbilisi, Georgia, 0144
    • Local Institution - 552
  • Tbilisi, Georgia, 0159
    • Local Institution - 793
  • Tbilisi, Georgia, 0160
    • Local Institution - 740
  • Tbilisi, Georgia, 0160
    • Local Institution - 784
  • Tbilisi, Georgia, 0160
    • Local Institution - 785
  • Tbilisi, Georgia, 0179
    • Local Institution - 335
  • Tbilisi, Georgia, 0180
    • Local Institution - 455
  • Tbilisi, Georgia, 0101
    • Local Institution - 248
  • Tbilisi, Georgia, 0112
    • Local Institution - 247
  • Tbilisi, Georgia, 0180
    • Local Institution - 249
  • Tbilisi, Georgia, 0101
    • Local Institution - 783
  • Tbilisi, Georgia, 0159
    • Local Institution - 781
  • Telavi, Georgia, 2200
    • Local Institution - 780
• Germany
  • Berlin, Germany, 10787
    • Local Institution - 629
  • Berlin, Germany, 12200
    • Local Institution - 653
  • Berlin, Germany, 13353
    • Local Institution - 648
  • Berlin, Germany, 14163
    • Local Institution - 628
  • Berlin, Germany, 10117
    • Local Institution - 626
  • Berlin, Germany, 10825
    • Local Institution - 665
  • Berlin, Germany, 14050
    • Local Institution - 650
  • Brandenburg, Germany, 14770
    • Local Institution - 664
  • Dachau, Germany, 85221
    • Local Institution - 732
  • Frankfurt, Germany, 60431
    • Local Institution - 662
  • Frankfurt, Germany, 60594
    • Local Institution - 654
  • Frankfurt am Main, Germany, 60313
    • Local Institution - 574
  • Frankfurt am Main, Germany, 60590
    • Local Institution - 657
  • Halle, Germany, 06108
    • Local Institution - 658
  • Halle, Germany, 06120
    • Local Institution - 656
  • Hamburg, Germany, 22559
    • Local Institution - 652
  • Hamburg, Germany, 20246
    • Local Institution - 659
  • Hanover, Germany, 30625
    • Local Institution - 591
  • Keil, Germany, 24105
    • Local Institution - 649
  • Leipzig, Germany, 04103
    • Local Institution - 337
  • Leipzig, Germany, 04103
    • Local Institution - 651
  • Ludwigshafen am Rhein, Germany, 67067
    • Local Institution - 655
  • Ludwigshafen am Rhein, Germany, 67067
    • Local Institution - 730
  • Mainz, Germany, 55131
    • Local Institution - 660
  • Münster, Germany, 48149
    • Local Institution - 667
  • Neuruppin, Germany, 16816
    • Local Institution - 620
  • Nürtingen, Germany, 72622
    • Local Institution - 584
  • Stuttgart, Germany, 70376
    • Local Institution - 661
  • Tübingen, Germany, 72076
    • Local Institution - 666
  • Ulm, Germany, 89081
    • Local Institution - 663
• Greece
  • Athens, Greece, 11 527
    • Local Institution - 790
  • Athens, Greece, 115 28
    • Local Institution - 588
  • Athens, Greece, 11527
    • Local Institution - 791
  • Athens, Greece, 18536
    • Local Institution - 792
  • Athens, Attiki, Greece, 15562
    • Local Institution - 592
  • Heraklion, Greece, 71 110
    • Local Institution - 787
  • Thessaloniki, Greece, 54642
    • Local Institution - 789
  • Thessaloniki, Greece, 56429
    • Local Institution - 788
• Hong Kong
  • Hong Kong, Hong Kong
    • Local Institution - 404
  • Kowloon, Hong Kong
    • Local Institution - 405
• Hungary
  • Budapest, Hungary, 1062
    • Local Institution - 803
  • Budapest, Hungary, 1088
    • Local Institution - 804
  • Budapest, Hungary, H-1036
    • Local Institution - 556
  • Békéscsaba, Hungary, 5600
    • Local Institution - 798
  • Gyula, Hungary, 5700
    • Local Institution - 555
  • Győr, Hungary, 9024
    • Local Institution - 801
  • Miskolc, Hungary, 3529
    • Local Institution - 797
  • Nagykanizsa, Hungary, H-8800
    • Local Institution - 800
  • Szekszárd, Hungary, 7100
    • Local Institution - 816
  • Szentes, Hungary, 6600
    • Local Institution - 805
  • Székesfehérvár, Hungary, 8000
    • Local Institution - 799
• India
  • Delhi, India, 110002
    • Local Institution - 457
  • New Delhi, India, 110029
    • Local Institution - 411
  • Andhra Pradesh
    • Hyderabad, Andhra Pradesh, India, 500084
      • Local Institution - 444
  • Gujarat
    • Surat, Gujarat, India, 395002
      • Local Institution - 407
  • Haryana
    • Gurgaon, Haryana, India, 122002
      • Local Institution - 332
  • Kerala
    • Kochi, Kerala, India, 682041
      • Local Institution - 445
  • Punjab
    • Ludhiana, Punjab, India, 141001
      • Local Institution - 446
  • Rajasthan
    • Jaipur, Rajasthan, India, 302004
      • Local Institution - 443
    • Jaipur, Rajasthan, India, 302006
      • Local Institution - 399
  • Tamil Nadu
    • Coimbatore, Tamil Nadu, India, 641044
      • Local Institution - 408
  • Telangana
    • Hyderabad, Telangana, India, 500032
      • Local Institution - 331
• Ireland
  • Dublin, Ireland, D09 V2N0
    • Local Institution - 973
  • Dublin
    • Dublin, Dublin, Ireland, DO4 T6F4
      • Local Institution - 975
• Israel
  • Afula, Israel, 18341
    • Local Institution - 343
  • Bat Yam, Israel, 5962025
    • Local Institution - 345
  • Beer Jacob, Israel, 73100
    • Local Institution - 346
  • Haifa, Israel, 3109601
    • Local Institution - 350
  • Jerusalem, Israel, 9362410
    • Local Institution - 347
  • Jerusalem, Israel, 91031
    • Local Institution - 339
  • Kfar Saba, Israel, 44281
    • Local Institution - 349
  • Nahariya, Israel, 22100
    • Local Institution - 344
  • Petah Tikva, Israel, 49100
    • Local Institution - 341
  • Ramat Gan, Israel, 52621
    • Local Institution - 342
  • Rehovot, Israel, 76100
    • Local Institution - 338
  • Tel Aviv, Israel, 64239
    • Local Institution - 340
• Italy
  • Bologna, Italy, 40138
    • Local Institution - 677
  • Brescia, Italy, 25123
    • Local Institution - 684
  • Brescia, Italy, 25124
    • Local Institution - 688
  • Castellana Grotte, Italy, 70013
    • Local Institution - 689
  • Catanzaro, Italy, 88100
    • Local Institution - 679
  • Chieti, Italy, 66100
    • Local Institution - 687
  • Messina, Italy, 98125
    • Local Institution - 674
  • Milan, Italy, 20089
    • Local Institution - 672
  • Milan, Italy, 20122
    • Local Institution - 686
  • Milan, Italy, 20132
    • Local Institution - 334
  • Monza, Italy, 20900
    • Local Institution - 678
  • Padua, Italy, 35128
    • Local Institution - 685
  • Palermo, Italy, 90146
    • Local Institution - 682
  • Pavia, Italy, 27100
    • Local Institution - 673
  • Roma, Italy, 00133
    • Local Institution - 681
  • Roma, Italy, 00168
    • Local Institution - 675
  • Rome, Italy, 00152
    • Local Institution - 671
  • Udine, Italy, 33100
    • Local Institution - 680
  • Varese, Italy, 21100
    • Local Institution - 670
  • Verona, Italy, 37024
    • Local Institution - 676
• Latvia
  • Riga, Latvia, LV-1002
    • Local Institution - 602
  • Riga, Latvia, LV-1006
    • Local Institution - 601
  • Riga, Latvia, LV-1038
    • Local Institution - 600
• Lithuania
  • Kaunas, Lithuania, LT-50009
    • Local Institution - 605
  • Klaipėda, Lithuania, LT-5808
    • Local Institution - 603
  • Vilnius, Lithuania, 08406
    • Local Institution - 607
  • Vilnius, Lithuania, LT-08661
    • Local Institution - 606
  • Vilnius, Lithuania, LT-10207
    • Local Institution - 604
• Mexico
  • Chihuahua City, Mexico, 31020
    • Local Institution - 528
  • Mexico City, Mexico, 6700
    • Local Institution - 448
  • México, Mexico, 07020
    • Local Institution - 527
  • Tlalpan, Mexico, 14080
    • Local Institution - 530
  • Jalisco
    • Zapapan, Jalisco, Mexico, 45030
      • Local Institution - 526
  • Nuevo León
    • Monterrey, Nuevo León, Mexico, 64610
      • Local Institution - 532
    • Monterrey, Nuevo León, Mexico, 64718
      • Local Institution - 525
    • Monterrey, Nuevo León, Mexico, C.P 64000
      • Local Institution - 447
    • Monterrey, Nuevo León, Mexico, C.P 64060
      • Local Institution - 449
  • Querétaro
    • Querétaro City, Querétaro, Mexico, 76070
      • Local Institution - 529
• Moldova
  • Chisinau, Moldova, MD-2068
    • Local Institution - 811
  • Chisinau, Moldova, MD2025
    • Local Institution - 809
  • Chisinau, Moldova, MD2025
    • Local Institution - 812
  • Chisinau, Moldova, MD2025
    • Local Institution - 813
• Netherlands
  • Amsterdam, Netherlands, 1081 HV
    • Local Institution - 952
  • Amsterdam, Netherlands, 1105 AZ
    • Local Institution - 955
  • Groningen, Netherlands, 9713 GZ
    • Local Institution - 956
  • Nijmegen, Netherlands, 6525 GA
    • Local Institution - 949
  • Sittard-Geleen, Netherlands, 6162 BG
    • Local Institution - 951
  • Tilburg, Netherlands, 5022 GC
    • Local Institution - 954
• Poland
  • Bialystok, Poland, 15-276
    • Local Institution - 820
  • Bochnia, Poland, 32-700
    • Local Institution - 818
  • Częstochowa, Poland, 42-202
    • Local Institution - 580
  • Elblag, Poland, 82-300
    • Local Institution - 988
  • Gdansk, Poland, 80-382
    • Local Institution - 579
  • Gdansk, Poland, 80-803
    • Local Institution - 978
  • Gdynia, Poland, 81-537
    • Local Institution - 577
  • Jelenia Góra, Poland, 58-500
    • Local Institution - 906
  • Józefów, Poland, 05-410
    • Local Institution - 757
  • Katowice, Poland, 40-040
    • Local Institution - 578
  • Katowice, Poland, 40-040
    • Local Institution - 238
  • Katowice, Poland, 40-660
    • Local Institution - 828
  • Katowice, Poland, 40-752
    • Local Institution - 819
  • Krakow, Poland, 30-363
    • Local Institution - 815
  • Krakow, Poland, 31-156
    • Local Institution - 823
  • Krakow, Poland, 31-501
    • Local Institution - 826
  • Ksawerów, Poland, 95-054
    • Local Institution - 834
  • Kłodzko, Poland, 57-300
    • Local Institution - 817
  • Lodz, Poland, 90-127
    • Local Institution - 581
  • Lodz, Poland, 93-034
    • Local Institution - 981
  • Lodz, Poland, 90-302
    • Local Institution - 829
  • Lodz, Poland, 91-839
    • Local Institution - 888
  • Lublin, Poland, 20-049
    • Local Institution - 760
  • Nowy Targ, Poland, 34-400
    • Local Institution - 976
  • Olsztyn, Poland, 10-561
    • Local Institution - 830
  • Opole, Poland, 45-819
    • Local Institution - 402
  • Oświęcim, Poland, 32-600
    • Local Institution - 400
  • Poznan, Poland, 60-529
    • Local Institution - 758
  • Poznan, Poland, 60-702
    • Local Institution - 575
  • Poznan, Poland, 61-293
    • Local Institution - 401
  • Rzeszów, Poland, 35-302
    • Local Institution - 963
  • Sopot, Poland, 81-756
    • Local Institution - 979
  • Sopot, Poland, 81756
    • Local Institution - 239
  • Szczecin, Poland, 71-270
    • Local Institution - 835
  • Szczecin, Poland, 71434
    • Local Institution - 235
  • Torun, Poland, 87-100
    • Local Institution - 822
  • Tychy, Poland, 43-100
    • Local Institution - 824
  • Ul. Piotrkowska 177, Poland, 90-447
    • Local Institution - 827
  • Warsaw, Poland, 02-018
    • Local Institution - 833
  • Warsaw, Poland, 04-730
    • Local Institution - 807
  • Warsaw, Poland, 00-189
    • Local Institution - 410
  • Warsaw, Poland, 04-501
    • Local Institution - 236
  • Warsaw, Poland, 04-501
    • Local Institution - 586
  • Warsaw, Poland, 01-192
    • Local Institution - 576
  • Warsaw, Poland, 02-653
    • Local Institution - 989
  • Wierzchosławice, Poland, 33-122
    • Local Institution - 893
  • Wroclaw, Poland, 50-053
    • Local Institution - 983
  • Wroclaw, Poland, 50-367
    • Local Institution - 984
  • Wroclaw, Poland, 50-381
    • Local Institution - 582
  • Wroclaw, Poland, 51-162
    • Local Institution - 982
  • Wroclaw, Poland, 53-114
    • Local Institution - 831
  • Wroclaw, Poland, 53-333
    • Local Institution - 987
  • Wroclaw, Poland, 54-144
    • Local Institution - 832
  • Lublin Voivodeship
    • Zamość, Lublin Voivodeship, Poland, 22-400
      • Local Institution - 403
    • Zamość, Lublin Voivodeship, Poland, 22-400
      • Local Institution - 597
• Portugal
  • Coimbra, Portugal, 3000-075
    • Local Institution - 959
  • Guimarães, Portugal, 4835-044
    • Local Institution - 958
  • Loures, Portugal, 2674-514
    • Local Institution - 961
  • Viana do Castelo, Portugal, 4904-858
    • Local Institution - 957
• Romania
  • Bucharest, Romania, 010719
    • Local Institution - 808
  • Bucharest, Romania, 010719
    • Local Institution - 836
  • Bucharest, Romania, 013823
    • Local Institution - 499
  • Bucharest, Romania, 021494
    • Local Institution - 795
  • Bucharest, Romania, 022328
    • Local Institution - 837
  • Bucharest, Romania, 050098
    • Local Institution - 839
  • Bucharest, Romania, 10825
    • Local Institution - 842
  • Cluj-Napoca, Romania, 400001
    • Local Institution - 838
  • Craiova, Romania, 200642
    • Local Institution - 843
  • Târgu Mureş, Romania, 540136
    • Local Institution - 840
• Russia
  • Barnaul, Russia, 656024
    • Local Institution - 871
  • Bataysk, Russia, 346880
    • Local Institution - 589
  • Chelyabinsk, Russia, 454021
    • Local Institution - 621
  • Chelyabinsk, Russia, 454076
    • Local Institution - 991
  • Chita, Russia, 672090
    • Local Institution - 598
  • Irkutsk, Russia, 664049
    • Local Institution - 848
  • Kaliningrad, Russia, 236016
    • Local Institution - 998
  • Kaluga, Russia, 248007
    • Local Institution - 882
  • Kazan', Russia, 420103
    • Local Institution - 892
  • Kemerovo, Russia, 650066
    • Local Institution - 849
  • Khanty-Mansiysk, Russia, 628012
    • Local Institution - 599
  • Krasnoyarsk, Russia, 660037
    • Local Institution - 927
  • Moscow, Russia, 105554
    • Local Institution - 566
  • Moscow, Russia, 111123
    • Local Institution - 851
  • Moscow, Russia, 117997
    • Local Institution - 873
  • Moscow, Russia, 119192
    • Local Institution - 870
  • Moscow, Russia, 123423
    • Local Institution - 869
  • Nizhny Novgorod, Russia, 603140
    • Local Institution - 990
  • Novosibirsk, Russia, 630007
    • Local Institution - 594
  • Novosibirsk, Russia, 630091
    • Local Institution - 853
  • Novosibirsk, Russia, 630117
    • Local Institution - 876
  • Omsk, Russia, 644024
    • Local Institution - 996
  • Orenburg, Russia, 460050
    • Local Institution - 875
  • Penza, Russia, 440026
    • Local Institution - 867
  • Petrozavodsk, Russia, 185019
    • Local Institution - 858
  • Pushkin, Russia, 196603
    • Local Institution - 859
  • Pyatigorsk, Russia, 357502
    • Local Institution - 960
  • Pyatigorsk, Russia, 357538
    • Local Institution - 846
  • Saint Petersburg, Russia, 191015
    • Local Institution - 863
  • Saint Petersburg, Russia, 191015
    • Local Institution - 993
  • Saint Petersburg, Russia, 194044
    • Local Institution - 862
  • Saint Petersburg, Russia, 194044
    • Local Institution - 868
  • Saint Petersburg, Russia, 194354
    • Local Institution - 847
  • Saint Petersburg, Russia, 195009
    • Local Institution - 857
  • Saint Petersburg, Russia, 195067
    • Local Institution - 845
  • Saint Petersburg, Russia, 195257
    • Local Institution - 856
  • Saint Petersburg, Russia, 196143
    • Local Institution - 879
  • Saint Petersburg, Russia, 196247
    • Local Institution - 878
  • Saint Petersburg, Russia, 197110
    • Local Institution - 874
  • Samara, Russia, 443001
    • Local Institution - 865
  • Samara, Russia, 443041
    • Local Institution - 844
  • Sochi, Russia, 354207
    • Local Institution - 866
  • Tomsk, Russia, 634063
    • Local Institution - 877
  • Tula, Russia, 300053
    • Local Institution - 806
  • Ufa, Russia, 450005
    • Local Institution - 881
  • Ufa, Russia, 450071
    • Local Institution - 861
  • Veliky Novgorod, Russia, 173008
    • Local Institution - 855
  • Vladimir, Russia, 600023
    • Local Institution - 935
  • Vladivostok, Russia, 690091
    • Local Institution - 999
  • Vladivostok, Russia, 690922
    • Local Institution - 986
  • Volgograd, Russia, 400107
    • Local Institution - 880
  • Yekaterinburg, Russia, 620075
    • Local Institution - 583
  • Yekaterinburg, Russia, 620109
    • Local Institution - 872
• Saudi Arabia
  • Dammam, Saudi Arabia, 32253
    • Local Institution - 534
  • Jeddah, Saudi Arabia, 22252
    • Local Institution - 537
  • Riyadh, Saudi Arabia, 12746
    • Local Institution - 536
  • Riyadh, Saudi Arabia, 14611
    • Local Institution - 535
• Senegal
  • Cape Town, Senegal, 7500
    • Local Institution - 546
• Serbia
  • Belgrade, Serbia, 11 080
    • Local Institution - 887
  • Belgrade, Serbia, 11000
    • Local Institution - 596
  • Belgrade, Serbia, 11000
    • Local Institution - 886
  • Belgrade, Serbia, 11000
    • Local Institution - 890
  • Belgrade, Serbia, 11 000
    • Local Institution - 241
  • Belgrade, Serbia, 11 080
    • Local Institution - 245
  • Belgrade, Serbia, 11000
    • Local Institution - 246
  • Kragujevac, Serbia, 34000
    • Local Institution - 891
  • Novi Sad, Serbia, 21 000
    • Local Institution - 884
  • Pančevo, Serbia, 26000
    • Local Institution - 885
  • Vršac, Serbia, 26300
    • Local Institution - 585
  • Zrenjanin, Serbia, 23 000
    • Local Institution - 889
• Slovakia
  • Bratislava, Slovakia, 820 07
    • Local Institution - 900
  • Bratislava, Slovakia, 82606
    • Local Institution - 894
  • Brezno, Slovakia, 97701
    • Local Institution - 895
  • Nitra, Slovakia, 94901
    • Local Institution - 899
  • Nové Zámky, Slovakia, 94002
    • Local Institution - 897
  • Prešov, Slovakia, 080 01
    • Local Institution - 898
  • Rimavská Sobota, Slovakia, 979 01
    • Local Institution - 896
• Slovenia
  • Celje, Slovenia, 3000
    • Local Institution - 904
• South Africa
  • Gauteng, South Africa, 1820
    • Local Institution - 543
  • Kempton Park, South Africa, 1619
    • Local Institution - 545
  • Pretoria, South Africa, 0001
    • Local Institution - 544
  • Pretoria, South Africa, 0084
    • Local Institution - 542
  • Pretoria, South Africa, 0181
    • Local Institution - 549
  • Somerset West, South Africa, 7130
    • Local Institution - 548
  • Val de Grace, South Africa, 0184
    • Local Institution - 547
• South Korea
  • Ansan, South Korea, 152-703
    • Local Institution - 437
  • Busan, South Korea, 49201
    • Local Institution - 441
  • Busan, South Korea, 49241
    • Local Institution - 434
  • Busan, South Korea, 612-030
    • Local Institution - 431
  • Daegu, South Korea, 705-030
    • Local Institution - 432
  • Guri-si, South Korea, 11923
    • Local Institution - 435
  • Seongnam-si, South Korea, 13620
    • Local Institution - 436
  • Seoul, South Korea, 06351
    • Local Institution - 433
  • Seoul, South Korea, 06591
    • Local Institution - 440
  • Seoul, South Korea, 120-752
    • Local Institution - 430
  • Seoul, South Korea, 138-736
    • Local Institution - 442
  • Seoul, South Korea, 3080
    • Local Institution - 438
  • Seoul, South Korea, 3181
    • Local Institution - 427
  • Seoul, South Korea, 7985
    • Local Institution - 439
  • Suwon, South Korea, 442723
    • Local Institution - 429
• Spain
  • Alicante, Spain, 03010
    • Local Institution - 703
  • Badalona, Spain, 08916
    • Local Institution - 690
  • Barcelona, Spain, 08022
    • Local Institution - 694
  • Córdoba, Spain, 14001
    • Local Institution - 702
  • Girona, Spain, 17007
    • Local Institution - 699
  • Las Palmas de Gran Canaria, Spain, 35012
    • Local Institution - 701
  • Madrid, Spain, 28040
    • Local Institution - 695
  • Madrid, Spain, 28006
    • Local Institution - 691
  • Madrid, Spain, 28046
    • Local Institution - 692
  • Majadahonda, Madrid, Spain, 28222
    • Local Institution - 693
  • San Cristóbal de La Laguna, Spain, 38320
    • Local Institution - 698
  • Santander, Spain, 39008
    • Local Institution - 706
  • Seville, Spain, 41009
    • Local Institution - 696
  • Seville, Spain, 41013
    • Local Institution - 705
  • Valencia, Spain, 46010
    • Local Institution - 697
  • Viladecans, Spain, 08840
    • Local Institution - 700
• Sweden
  • Stockholm, Sweden, 112 81
    • Local Institution - 625
• Switzerland
  • Bern, Switzerland, 3001
    • Local Institution - 967
  • Sankt Gallen, Switzerland, 9007
    • Local Institution - 968
  • Zurich, Switzerland, 8091
    • Local Institution - 969
• Taiwan
  • Kaohsiung City, Taiwan, 82445
    • Local Institution - 460
  • Kaohsiung, San Ming Dist., Taiwan, 807
    • Local Institution - 463
  • Kozlu, Taiwan, 67000
    • Local Institution - 363
  • Niao-Sung Hsiang Kaohsiung County, Taiwan, 83301
    • Local Institution - 461
  • Tainan, Taiana, Taiwan, 704
    • Local Institution - 459
  • Taoyuan, Taiwan, 33305
    • Local Institution - 462
  • Tapei, Taiwan, 10002
    • Local Institution - 465
  • Tapei, Beitou Dist., Taiwan, 11217
    • Local Institution - 464
• Turkey (Türkiye)
  • Ankara, Turkey (Türkiye), 01660
    • Local Institution - 357
  • Ankara, Turkey (Türkiye), 06590
    • Local Institution - 356
  • Bursa, Turkey (Türkiye), 16059
    • Local Institution - 360
  • Elâzığ, Turkey (Türkiye), 23119
    • Local Institution - 365
  • Istanbul, Turkey (Türkiye), 34093
    • Local Institution - 362
  • Istanbul, Turkey (Türkiye), 34098
    • Local Institution - 358
  • Istanbul, Turkey (Türkiye), 34668
    • Local Institution - 361
  • Istanbul, Turkey (Türkiye), 34840
    • Local Institution - 355
  • Izmit/Kocaeli, Turkey (Türkiye), 41380
    • Local Institution - 354
  • Kadiköy/Istanbul, Turkey (Türkiye), 41380
    • Local Institution - 353
  • Trabzon, Turkey (Türkiye), 61080
    • Local Institution - 359
• Ukraine
  • Chernivtsi, Ukraine, 58001
    • Local Institution - 922
  • Chernivtsi, Ukraine, 58001
    • Local Institution - 914
  • Dnipropetrovsk, Ukraine, 49074
    • Local Institution - 950
  • Ivano-Frankivsk, Ukraine, 76008
    • Local Institution - 929
  • Ivano-Frankivsk, Ukraine, 76008
    • Local Institution - 229
  • Ivano-Frankivsk, Ukraine, 76018
    • Local Institution - 912
  • Kharkiv, Ukraine, 61037
    • Local Institution - 965
  • Kharkiv, Ukraine, 61018
    • Local Institution - 919
  • Khmelnytskyi, Ukraine, 29000
    • Local Institution - 920
  • Kropyvnytskyi, Ukraine, 25006
    • Local Institution - 933
  • Kyiv, Ukraine, 01601
    • Local Institution - 923
  • Kyiv, Ukraine, 02002
    • Local Institution - 563
  • Kyiv, Ukraine, 03037
    • Local Institution - 564
  • Kyiv, Ukraine, 04107
    • Local Institution - 977
  • Kyiv, Ukraine, 01030
    • Local Institution - 901
  • Kyiv, Ukraine, 02000
    • Local Institution - 915
  • Kyiv, Ukraine, 02002
    • Local Institution - 243
  • Kyiv, Ukraine, 02175
    • Local Institution - 911
  • Kyiv, Ukraine, 03037
    • Local Institution - 244
  • Kyiv, Ukraine, 04053
    • Local Institution - 918
  • Kyiv, Ukraine, 04107
    • Local Institution - 908
  • Kyiv, Ukraine, 4210
    • Local Institution - 562
  • Lutsk, Ukraine, 43005
    • Local Institution - 590
  • Lutsk, Ukraine, 43005
    • Local Institution - 240
  • Lviv, Ukraine, 79010
    • Local Institution - 974
  • Lviv, Ukraine, 79010
    • Local Institution - 234
  • Lviv, Ukraine, 79059
    • Local Institution - 910
  • Odesa, Ukraine, 65025
    • Local Institution - 902
  • Odesa, Ukraine, 65025
    • Local Institution - 242
  • Poltava, Ukraine, 36011
    • Local Institution - 905
  • Ternopil, Ukraine, 46008
    • Local Institution - 934
  • Vinnytsia, Ukraine, 21018
    • Local Institution - 924
  • Vinnytsia, Ukraine, 02029
    • Local Institution - 909
  • Vinnytsia, Ukraine, 21018
    • Local Institution - 224
  • Vinnytsia, Ukraine, 21018
    • Local Institution - 971
  • Vinnytsia, Ukraine, 21009
    • Local Institution - 932
  • Zaporizhia, Ukraine, 69063
    • Local Institution - 587
  • Zaporizhzhya, Ukraine, 69600
    • Local Institution - 925
• United Kingdom
  • Birmingham, United Kingdom, B15 2SQ
    • Local Institution - 557
  • Bristol, United Kingdom, BS2 8HW
    • Local Institution - 714
  • Cardiff, United Kingdom, CF15 9SS
    • Local Institution - 560
  • Chorley, United Kingdom, PR7 7NA
    • Local Institution - 558
  • Corbridge Road, United Kingdom, NE46 1QJ
    • Local Institution - 559
  • Dundonald, United Kingdom, BT16 1RH
    • Local Institution - 712
  • Glasgow, United Kingdom, G51 4TF
    • Local Institution - 713
  • Lancashire Blackpool, United Kingdom, FY3 8NR
    • Local Institution - 716
  • London, United Kingdom, E1 1BB
    • Local Institution - 722
  • London, United Kingdom, SE1 9RT
    • Local Institution - 715
  • North Manchester Science Park, United Kingdom, M15 6SX
    • Local Institution - 561
  • Shrewsbury, United Kingdom, SY38XQ
    • Local Institution - 593
  • Torquay, United Kingdom, TQ2 7AA
    • Local Institution - 718
  • Hampshire
    • Southampton, Hampshire, United Kingdom, SO16 6YD
      • Local Institution - 723
  • LND
    • London, LND, United Kingdom, NW1 2BU
      • Local Institution - 729
• United States
  • Arizona
    • Peoria, Arizona, United States, 85381
      • Holland Center for Family Health
    • Scottsdale, Arizona, United States, 85258
      • Local Institution - 202
  • Arkansas
    • North Little Rock, Arkansas, United States, 72117
      • Local Institution - 026
  • California
    • Camarillo, California, United States, 93012
      • Local Institution - 284
    • Chula Vista, California, United States, 91911
      • Sharp Chula Vista Medical Center
    • Garden Grove, California, United States, 92843
      • Local Institution - 039
    • La Jolla, California, United States, 92037
      • UCSD Medical Center
    • La Mesa, California, United States, 91942
      • San Diego Clinical Trials
    • Lancaster, California, United States, 93534
      • Local Institution - 010
    • Los Angeles, California, United States, 90045
      • Southern California Research Institute Medical Group, Inc.
    • Los Angeles, California, United States, 90048
      • Matrix Clinical Research Inc
    • Los Angeles, California, United States, 90027
      • Local Institution - 061
    • Los Angeles, California, United States, 90067
      • Local Institution - 110
    • Mission Hills, California, United States, 91345
      • Facey Medical Foundation (Parent)
    • Mission Viejo, California, United States, 92691
      • ABS Health, LLC
    • Oceanside, California, United States, 92056
      • Alliance Clinical Research
    • Orange, California, United States, 92868
      • Local Institution - 027
    • Palo Alto, California, United States, 94304
      • Palo Alto Center-Palo Alto Medical Foundation Research Institute
    • Pasadena, California, United States, 91105
      • Havana Research Institute LLC
    • Rialto, California, United States, 92377
      • Local Institution - 006
    • Roseville, California, United States, 95661
      • Sutter Medical Group
    • Sacramento, California, United States, 95817
      • Local Institution - 280
    • San Diego, California, United States, 92123
      • Local Institution - 003
    • San Francisco, California, United States, 94158
      • Local Institution - 281
    • West Covina, California, United States, 91790
      • New Hope Research Development
  • Colorado
    • Colorado Springs, Colorado, United States, 80907
      • Local Institution - 065
    • Lakewood, Colorado, United States, 80228
      • Local Institution - 297
  • Connecticut
    • Bristol, Connecticut, United States, 06010
      • Local Institution - 182
    • Bristol, Connecticut, United States, 06010
      • Local Institution - 225
    • New Haven, Connecticut, United States, 06510
      • Local Institution - 091
  • Florida
    • Clearwater, Florida, United States, 33765
      • Clinical Research of West Florida
    • Clearwater, Florida, United States, 33756-3839
      • Local Institution - 062
    • Clermont, Florida, United States, 34711
      • South Lake Pain Institute
    • Cutler Bay, Florida, United States, 33157
      • American Research Institute Inc
    • Doral, Florida, United States, 33166
      • Universal Axon Clinical Research
    • Edgewater, Florida, United States, 32132
      • Riverside Clinical Research
    • Gainesville, Florida, United States, 32608
      • Local Institution - 218
    • Hialeah, Florida, United States, 33016
      • Harmony Medical Research Institute
    • Hialeah, Florida, United States, 33010
      • Local Institution - 203
    • Hialeah, Florida, United States, 33016
      • Floridian Clinical Research LLC
    • Hollywood, Florida, United States, 33021
      • Local Institution - 179
    • Homestead, Florida, United States, 33033
      • Vista Health Research
    • Kissimmee, Florida, United States, 34759
      • SIH Research
    • Largo, Florida, United States, 33777
      • Local Institution - 016
    • Lighthouse PT, Florida, United States, 33064
      • Local Institution - 067
    • Maitland, Florida, United States, 32751
      • Center For Advanced Gastroenterology
    • Miami, Florida, United States, 33126
      • LCC Medical Research Institute, LLC
    • Miami, Florida, United States, 33176
      • Vista Health Research
    • Miami, Florida, United States, 33125
      • LMG Research
    • Miami, Florida, United States, 33166
      • Local Institution - 175
    • Miami, Florida, United States, 33125
      • Local Institution - 199
    • Miami, Florida, United States, 33156
      • Local Institution - 169
    • Miami Springs, Florida, United States, 33166
      • Local Institution - 044
    • Naples, Florida, United States, 34109
      • Advanced Research for Health Improvement
    • New Port Richey, Florida, United States, 34655
      • Local Institution - 192
    • New Smyrna Beach, Florida, United States, 32168
      • Local Institution - 214
    • Orlando, Florida, United States, 32810
      • Local Institution - 200
    • Orlando, Florida, United States, 32819
      • Local Institution - 076
    • Palmetto Bay, Florida, United States, 33157
      • Local Institution - 002
    • Pinellas Park, Florida, United States, 33781
      • Theia Clinical Research, LLC
    • Port Orange, Florida, United States, 32127
      • Local Institution - 098
    • Sunrise, Florida, United States, 33351
      • Precision Clinical Research, LLC.
    • Tampa, Florida, United States, 33612
      • Apex Clinical Research
    • Tampa, Florida, United States, 33612-4799
      • Local Institution - 183
    • Tampa, Florida, United States, 33614
      • Local Institution - 107
    • Tampa, Florida, United States, 33612
      • Local Institution - 226
    • Tampa, Florida, United States, 33614
      • Local Institution - 149
    • Weeki Wachee, Florida, United States, 34607
      • Local Institution - 114
  • Georgia
    • Atlanta, Georgia, United States, 30308
      • Consultative Gastroenterology
    • Atlanta, Georgia, United States, 30322
      • Local Institution - 037
    • Atlanta, Georgia, United States, 30322
      • Local Institution - 220
    • Atlanta, Georgia, United States, 30322
      • Local Institution - 222
    • Atlanta, Georgia, United States, 30342
      • Local Institution - 019
    • Atlanta, Georgia, United States, 30342
      • Local Institution - 063
    • Columbus, Georgia, United States, 31904
      • Local Institution - 074
    • Decatur, Georgia, United States, 30030
      • Local Institution - 143
    • Macon, Georgia, United States, 31201
      • Local Institution - 028
  • Idaho
    • Idaho Falls, Idaho, United States, 83404
      • Local Institution - 115
  • Illinois
    • Chicago, Illinois, United States, 60637
      • Local Institution - 022
    • Chicago, Illinois, United States, 60612
      • Local Institution - 194
    • Chicago, Illinois, United States, 60622
      • Local Institution - 036
    • Urbana, Illinois, United States, 61801
      • Carle Foundation Hospital
  • Indiana
    • Evansville, Indiana, United States, 47714
      • Local Institution - 092
    • Indianapolis, Indiana, United States, 46202
      • Local Institution - 033
  • Iowa
    • Clive, Iowa, United States, 50325
      • Iowa Digestive Disease Center
  • Kansas
    • Topeka, Kansas, United States, 66606
      • Local Institution - 070
  • Kentucky
    • Lexington, Kentucky, United States, 40536-0298
      • Local Institution - 155
  • Louisiana
    • Baton Rouge, Louisiana, United States, 70809
      • Local Institution - 020
    • Houma, Louisiana, United States, 70360
      • CroNola LLC
    • Lake Charles, Louisiana, United States, 70601
      • Centex Studies, Inc.
    • Lake Charles, Louisiana, United States, 70601
      • Clinical Trials of SW Louisiana LLC
    • Marrero, Louisiana, United States, 70072
      • Tandem Clinical Research, LLC
    • New Orleans, Louisiana, United States, 70125
      • NOLA Research Works
  • Maryland
    • Baltimore, Maryland, United States, 21224
      • Local Institution - 278
    • Catonsville, Maryland, United States, 21228
      • Local Institution - 129
    • Glen Burnie, Maryland, United States, 21061
      • Local Institution - 282
  • Massachusetts
    • Chestnut Hill, Massachusetts, United States, 02467
      • Local Institution - 142
    • North Worcester, Massachusetts, United States, 01655
      • Local Institution - 228
    • Springfield, Massachusetts, United States, 01199
      • Local Institution - 286
    • Worcester, Massachusetts, United States, 01655
      • Local Institution - 024
  • Michigan
    • Caro, Michigan, United States, 48723
      • Local Institution - 191
    • Kalamazoo, Michigan, United States, 49008
      • Local Institution - 167
    • Novi, Michigan, United States, 48377
      • Local Institution - 005
    • Southfield, Michigan, United States, 48034
      • Local Institution - 108
    • Wyoming, Michigan, United States, 49519
      • Local Institution - 301
    • Ypsilanti, Michigan, United States, 48197
      • Local Institution - 300
  • Minnesota
    • Minneapolis, Minnesota, United States, 55455
      • Local Institution - 095
    • Rochester, Minnesota, United States, 55905
      • Local Institution - 045
  • Mississippi
    • Jackson, Mississippi, United States, 39216
      • Local Institution - 274
  • Missouri
    • Kansas City, Missouri, United States, 64111
      • Local Institution - 198
    • St Louis, Missouri, United States, 63110
      • Local Institution - 029
  • Nevada
    • Las Vegas, Nevada, United States, 89145
      • Internal Medicine Specialists
  • New Hampshire
    • Lebanon, New Hampshire, United States, 03756
      • Local Institution - 040
  • New Jersey
    • Englewood, New Jersey, United States, 07631
      • Local Institution - 215
  • New York
    • Brooklyn, New York, United States, 11235
      • Local Institution - 144
    • Great Neck, New York, United States, 11021
      • Local Institution - 009
    • Hartsdale, New York, United States, 10530
      • Local Institution - 054
    • New York, New York, United States, 10016
      • Concorde Medical Group
    • New York, New York, United States, 10010
      • Weill Cornell Medical College
    • New York, New York, United States, 10024
      • TrialSpark
    • New York, New York, United States, 10021
      • Local Institution - 105
    • New York, New York, United States, 10075
      • Local Institution - 043
    • North Massapequa, New York, United States, 11758-1802
      • Local Institution - 060
    • Orchard Park, New York, United States, 14127
      • Circuit Clinical
    • The Bronx, New York, United States, 10468
      • Advantage Clinical Trials
  • North Carolina
    • Asheville, North Carolina, United States, 28801
      • Local Institution - 017
    • Charlotte, North Carolina, United States, 28209
      • Local Institution - 156
    • Charlotte, North Carolina, United States, 28204
      • Local Institution - 152
    • Charlotte, North Carolina, United States, 28207
      • Local Institution - 055
    • Greenville, North Carolina, United States, 27834
      • Local Institution - 133
    • Raleigh, North Carolina, United States, 27612
      • Local Institution - 302
    • Winston-Salem, North Carolina, United States, 27103
      • Local Institution - 052
  • Ohio
    • Beachwood, Ohio, United States, 44122
      • Great Lakes Medical Research, LLC
    • Cincinnati, Ohio, United States, 45219
      • Local Institution - 291
    • Cleveland, Ohio, United States, 44195
      • Local Institution - 018
    • Dayton, Ohio, United States, 45417
      • Local Institution - 170
    • Hilliard, Ohio, United States, 43026
      • Local Institution - 049
    • Mentor, Ohio, United States, 44060
      • Great Lakes Gastroenterology
    • Middleburg Heights, Ohio, United States, 44130
      • Local Institution - 141
    • Warren, Ohio, United States, 44483
      • Great Lakes Medical Research, LLC
  • Oklahoma
    • Norman, Oklahoma, United States, 73071
      • Local Institution - 087
    • Oklahoma City, Oklahoma, United States, 73102
      • Local Institution - 294
    • Oklahoma City, Oklahoma, United States, 73104
      • Local Institution - 208
    • Oklahoma City, Oklahoma, United States, 73112
      • Local Institution - 131
    • Tulsa, Oklahoma, United States, 74136
      • Local Institution - 185
    • Tulsa, Oklahoma, United States, 74137
      • Local Institution - 217
  • Oregon
    • Portland, Oregon, United States, 97239
      • Local Institution - 113
  • Pennsylvania
    • Hershey, Pennsylvania, United States, 17033
      • Local Institution - 197
    • Philadelphia, Pennsylvania, United States, 19104
      • University of Pennsylvania Cancer Center
    • State College, Pennsylvania, United States, 16803
      • Penn State University Milton S Hershey Medical Center
  • Rhode Island
    • Providence, Rhode Island, United States, 02904
      • Local Institution - 253
  • South Carolina
    • Charleston, South Carolina, United States, 29425
      • Local Institution - 289
  • Tennessee
    • Nashville, Tennessee, United States, 37212
      • Vanderbilt University Medical Center
    • Nashville, Tennessee, United States, 37211
      • Local Institution - 121
    • Union City, Tennessee, United States, 38261
      • Advanced Gastroenterology
  • Texas
    • Austin, Texas, United States, 78742
      • Local Institution - 158
    • Fort Sam Houston, Texas, United States, 78234
      • Local Institution - 034
    • Houston, Texas, United States, 77098
      • Gulf Coast Research Group LLC
    • Houston, Texas, United States, 77058
      • Centex Studies, Inc.
    • Houston, Texas, United States, 77043
      • Biopharma Informatic Inc. Research Center
    • Houston, Texas, United States, 77089
      • Local Institution - 196
    • Houston, Texas, United States, 77030
      • Local Institution - 056
    • Houston, Texas, United States, 77030
      • Local Institution - 150
    • Houston, Texas, United States, 77074
      • Local Institution - 303
    • Houston, Texas, United States, 77084
      • Local Institution - 088
    • Houston, Texas, United States, 77070
      • GI Specialists of Houston
    • Pasadena, Texas, United States, 77505
      • Accurate Clinical Research Inc
    • Richardson, Texas, United States, 75082
      • Local Institution - 071
    • San Antonio, Texas, United States, 78229
      • Local Institution - 178
    • San Antonio, Texas, United States, 78215
      • Local Institution - 085
    • San Antonio, Texas, United States, 78229-4894
      • Local Institution - 223
    • Southlake, Texas, United States, 76092
      • Local Institution - 007
    • Temple, Texas, United States, 76508
      • Local Institution - 181
    • Tyler, Texas, United States, 75701
      • Local Institution - 073
  • Utah
    • Riverton, Utah, United States, 84065
      • Local Institution - 292
    • Salt Lake City, Utah, United States, 84132
      • Local Institution - 025
  • Virginia
    • Gainesville, Virginia, United States, 20155
      • Local Institution - 189
    • Lynchburg, Virginia, United States, 24502
      • Local Institution - 030
    • Manassas, Virginia, United States, 20110
      • Local Institution - 298
    • Petersburg, Virginia, United States, 23805
      • Summit Clinical Research, LLC
    • Reston, Virginia, United States, 20191
      • The Gastroenterology Group
    • Richmond, Virginia, United States, 23249
      • Local Institution - 072
    • Roanoke, Virginia, United States, 24016
      • Local Institution - 172
    • Suffolk, Virginia, United States, 23434
      • Virginia Gastroenterology Institute PC
    • Williamsburg, Virginia, United States, 23188
      • Local Institution - 296
  • Washington
    • Spokane, Washington, United States, 99204
      • Local Institution - 125
  • Wisconsin
    • Grafton, Wisconsin, United States, 53024
      • Aurora Health Care Aurora Research
    • La Crosse, Wisconsin, United States, 54601
      • Local Institution - 089

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 75 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No

Description

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit: www.BMSStudyConnect.com

Inclusion Criteria:

• Fulfilled the inclusion criteria at time of entry into the induction study and completed the week 12 efficacy assessments of the induction study
• In clinical response and/or clinical remission and/or an average daily stool frequency score ≤ 3 and an average abdominal pain score ≤ 1 with abdominal pain and stool frequency no worse than baseline at Week 12 of the Induction Study

Exclusion Criteria:

• Partial or total colectomy, small bowel resection, or an ostomy since day 1 of the induction studies or has developed a symptomatic fistula
• Had a rectal steroid therapy, rectal 5-aminosalicylates, parenteral corticosteroids, immunomodulatory agents, investigational agents or apheresis

Other protocol-defined inclusion/exclusion criteria apply

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Quadruple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Placebo Comparator: Placebo	Other: Placebo; Specified dose on specified days
Experimental: Ozanimod	Drug: Ozanimod; Specified dose on specified days

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Percentage of Participants Who Achieve Crohn's Disease Activity Index (CDAI) Score < 150 at Week 52 as Observed	The CDAI is a composite score that is used to measure the clinical activity of Crohn's disease (CD). The CDAI uses a questionnaire with 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. The sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Additionally, the remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome.	Week 52
Percentage of Participants With a Simple Endoscopic Score for Crohn's Disease (SES-CD) Score Decrease From Baseline ≥ 50% Based on Observed Cases and Robarts Observed Scores	The SES-CD assessed the degree of inflammation. The SES-CD assesses the following 4 components: size of ulcers, ulcerated surface, affected surface, and presence of narrowing. Each of these components was scored on a scale of 0 (none/unaffected) to 3 (worst). In the SES-CD, each of these 4 components are assessed in the five segments: ileum, right colon, transverse colon, left colon, and rectum. The SES-CD was the sum of the individual scores of each of the components across the five segments. The range of SES-CD scores was 0 - 12 for each segment, and 0 - 60 for the overall SES-CD score, with larger scores indicating greater degree of inflammation. Baseline was defined as the last assessment prior to the start time of the first drug administration if time of measurement is available else the last assessment prior to or on the date of the first drug administration.	Week 52

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Percentage of Participants With CDAI Reduction From Baseline ≥ 100 Points or CDAI Score <150 at Week 52 as Observed	The CDAI is a composite score that is used to measure the clinical activity of Crohn's disease (CD). The CDAI uses a questionnaire with 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. The sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Additionally, the remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome.	Week 52
Percentage of Participants With Average Daily Abdominal Pain Score ≤1point and Average Daily Stool Frequency ≤ 3 Points With Abdominal Pain and Stool Frequency no Worse Than Baseline at Week 52	Abdominal pain (AP) and stool frequency (SF) clinical remission was defined as average daily abdominal pain score ≤ 1 point, and average daily stool frequency ≤3 times with AP and SF no worse than baseline at Week 12. Participants entered responses in diaries daily. The 7 days entries prior to visit were considered for calculating average AP score and SF. The AP was graded on severity of 0 (none) to 3 (severe) scale and SF was defined number of liquid or soft stools per day.	Week 52
Percentage of Participants With With CDAI Score < 150 at Week 52, While Remaining Corticosteroid Free in the 12 Weeks Prior to Week 52 Among All Participants at Maintenance Day 1	Abdominal pain (AP) and stool frequency (SF) clinical remission was defined as average daily abdominal pain score ≤ 1 point, and average daily stool frequency ≤3 times with AP and SF no worse than baseline at Week 12. Participants entered responses in diaries daily. The 7 days entries prior to visit were considered for calculating average AP score and SF. The AP was graded on severity of 0 (none) to 3 (severe) scale and SF was defined number of liquid or soft stools per day.	Week 52
Percentage of Participants With CDAI Score < 150 at Week 52 in Participants With CDAI Score <150 at Maintenance Day 1	The CDAI is a composite score that is used to measure the clinical activity of Crohn's disease (CD). The CDAI uses a questionnaire with 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. The sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Additionally, the remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome.	Week 52
Percentage of Participants With Simple Endoscopic Score for Crohn's Disease (SES-CD) ≤ 4 Points and SES-CD Decrease From Baseline ≥ 2points With no SES-CD Subscore > 1 Point at Week 52 Based on Observed Cases	The SES-CD score is a way to measure how severe a person's bowel disease is. It looks at five different parts of the bowel and checks for ulcer size, ulcerated surface, inflamed surface, and stenosis. Each is given a score from 0 to 3 based on how bad the disease is. These scores are then added together for a total score ranging from 0 to 60. Higher scores indicate more severe disease.	Week 52
Percentage of Participants With CDAI Score < 150 and SES-CD Decrease From Baseline ≥50% at Week 52 Based on Observed Cases and Robarts Observed Scores	CDAI is a composite score used to measure the clinical activity of Crohn's disease (CD). It assess 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. Sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome. SES-CD score is a way to measure how severe a person's bowel disease is. It looks at five different parts of the bowel. Each is given a score from 0 to 3 based on how bad the disease is. These scores are then added together for a total score ranging from 0 to 60. Higher scores indicate more severe disease.	Week 52
Percentage of Participants With Average Daily AP Score ≤ 1 Point, and Average Daily Stool Frequency Score ≤ 3 Points With AP and SF no Worse Than Baseline and SES-CD ≤ 4 Points and SES-CD Decrease ≥2 Points With no SES-CD Subscore >1 Point at Week 52	Abdominal pain (AP) and stool frequency (SF) clinical remission was defined as average daily abdominal pain score ≤ 1 point, and average daily stool frequency ≤ 3 times with AP and SF no worse than baseline at Week 12. Participants entered responses in diaries daily. The 7 days entries prior to visit were considered for calculating average AP score and SF. The AP was graded on severity of 0 (none) to 3 (severe) scale and SF was defined number of liquid or soft stools per day. The SES-CD has 4 components size of ulcers, ulcerated surface, affected surface, presence of narrowing. Each component was scored on scale of 0 (none) to 3 (worst). In SES-CD, each of 4 components are assessed in the five segments: ileum, right, transverse, left colon, and rectum. The SES-CD was the sum of the individual scores of each of the components across the five segments. The range of SES-CD scores was 0 - 12 for each segment, and 0 - 60 for overall, with larger scores show greater degree of inflammation.	Week 52
Percentage of Participants With CDAI Reduction From Baseline ≥ 100 Points or CDAI Score <150 and SES-CD Decrease From Baseline ≥ 50% at Week 52	CDAI is a composite score used to measure the clinical activity of Crohn's disease (CD). It assess 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. Sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome. SES-CD score is a way to measure how severe a person's bowel disease is. It looks at five different parts of the bowel. Each is given a score from 0 to 3 based on how bad the disease is. These scores are then added together for a total score ranging from 0 to 60. Higher scores indicate more severe disease.	Week 52
Percentage of Participants With CDAI Reduction From Baseline ≥ 70 Points at Week 52 Based on Observed Cases	CDAI is a composite score used to measure the clinical activity of Crohn's disease (CD). It assess 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. Sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome.	Week 52
Percentage of Participants With With CDAI Score < 150 at Week 52, While Remaining Corticosteroid Free in the 12 Weeks Prior to Week 52 Among Subjects Using Corticosteroids at Maintenance Day 1	CDAI is a composite score used to measure the clinical activity of Crohn's disease (CD). It assess 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. Sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome.	Week 52
Percentage of Participants With Mucosal Healing (SES-CD ≤ 4 Points and SES-CD Decrease ≥2 Points With no SES-CD Subscore > 1 Point) and Histologic Improvement Based on Robarts Histologic Index (RHI) at Week 52	The SES-CD assessed the degree of inflammation. The SES-CD assesses the following 4 components: size of ulcers, ulcerated surface, affected surface, and presence of narrowing. Each of these components was scored on a scale of 0 (none/unaffected) to 3 (worst). In the SES-CD, each of these 4 components are assessed in the five segments: ileum, right colon, transverse colon, left colon, and rectum. The SES-CD was the sum of the individual scores of each of the components across the five segments. The range of SES-CD scores was 0 - 12 for each segment, and 0 - 60 for the overall SES-CD score, with larger scores indicating greater degree of inflammation. Baseline was defined as the last assessment prior to the start time of the first drug administration if time of measurement is available else the last assessment prior to or on the date of the first drug administration.	Week 52
Time to Relapse (an Increase in CDAI Score From Maintenance Day 1 ≥100 Points and CDAI Score >220, SES-CD ≥ 6 [or ≥4 if Isolated Ileal Disease]), and Exclusion of Other Causes of an Increase in Disease Activity Unrelated to Underlying CD	CDAI is a composite score used to measure the clinical activity of Crohn's disease (CD). It assess 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. Sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome. SES-CD score is a way to measure how severe a person's bowel disease is. It looks at five different parts of the bowel. Each is given a score from 0 to 3 based on how bad the disease is. These scores are then added together for a total score ranging from 0 to 60. Higher scores indicate more severe disease.	Week 52
Percentage of Participants With a Crohn's Disease Endoscopic Index of Severity (CDEIS) Decrease From Baseline ≥ 50% at Week 52	CDEIS is an index for determining the severity of Crohn's disease with endoscopic localization to ileum and colon. The CDEIS divides the intestine into 5 segments: rectum, sigmoid and left colon, transverse colon, right colon, and ileum. Four variables are assessed in each segment: the presence of deep ulceration, the presence of superficial ulceration, the percentage of ulcerated surface, and the percentage of surface affected by CD, indicated on 10-cm visual analogue scales. In addition, the presence of ulcerated stenosis and the presence of nonulcerated stenosis are also assessed over the entire intestine. These factors are weighted and summed to calculate the total score ranging from 0- 44, with higher scores indicating more severe disease.	Week 52
Percentage of Participants With CDAI Score < 150 at Week 52 and at ≥ 80% of Visits Between Week 8 and Week 52, Inclusive, in Participants With CDAI Score < 150 at Maintenance Day 1	The CDAI is a composite score that is used to measure the clinical activity of Crohn's disease (CD). The CDAI uses a questionnaire with 8 disease activity variables: number of soft/liquid stools, severity of abdominal pain, general well-being, presence of complications, need for antidiarrheal drugs, presence of an abdominal mass, hematocrit, and deviation in body weight. The sub scores of number of soft/liquid stool, severity of abdominal pain (0 \[none\] to 3 \[Severe\]), general well-being (0 \[well\] to 4 \[terrible\] were summed over the 7 days prior to each visit. Additionally, the remaining predictors were also noted and weighted to create the total CDAI score which ranged from 0-600 with a higher score indicating a worse outcome.	Week 52
Percentage of Participants With Average Daily Abdominal Pain Score ≤ 1 Point and Average Daily Stool Frequency Score ≤3 Points With Abdominal Pain and Stool Frequency no Worse Than Baseline and SES-CD Decrease From Baseline ≥ 50% at Week 52	Abdominal pain (AP) and stool frequency (SF) clinical remission was defined as average daily abdominal pain score ≤ 1 point, and average daily stool frequency ≤3 times with AP and SF no worse than baseline. Participants entered responses in diaries daily. The 7 days entries prior to visit were considered for calculating average AP score and SF. The AP was graded on severity of 0 (none) to 3 (severe) scale and SF was defined number of liquid or soft stools per day. SES-CD score is a way to measure how severe a person's bowel disease is. It looks at five different parts of the bowel. Each is given a score from 0 to 3 based on how bad the disease is. These scores are then added together for a total score ranging from 0 to 60. Higher scores indicate more severe disease.	Week 52

Collaborators and Investigators

• Sponsor: Celgene
• Investigators: Study Director: Bristol-Myers Squibb, Bristol-Myers Squibb

Publications and helpful links

General Publications

• Feagan BG, Schreiber S, Afzali A, Rieder F, Hyams J, Kollengode K, Pearlman J, Son V, Marta C, Wolf DC, D'Haens GG. Ozanimod as a novel oral small molecule therapy for the treatment of Crohn's disease: The YELLOWSTONE clinical trial program. Contemp Clin Trials. 2022 Nov;122:106958. doi: 10.1016/j.cct.2022.106958. Epub 2022 Oct 5.

Helpful Links

• BMS Clinical Trial Information
• BMS Clinical Trial Patient Recruiting

Study record dates

Study Major Dates

• Study Start (Actual): June 27, 2018
• Primary Completion (Actual): October 3, 2024
• Study Completion (Actual): October 3, 2024

Study Registration Dates

• First Submitted: February 26, 2018
• First Submitted That Met QC Criteria: March 12, 2018
• First Posted (Actual): March 13, 2018

Study Record Updates

• Last Update Posted (Estimated): October 9, 2025
• Last Update Submitted That Met QC Criteria: September 22, 2025
• Last Verified: September 1, 2025

More Information

Terms related to this study

• Keywords: Crohn's Disease; Crohn Disease; Oral; Ozanimod; Moderately active; Severely active; RPC01; RPC01-3203
• Additional Relevant MeSH Terms: Intestinal Diseases; Digestive System Diseases; Gastrointestinal Diseases; Gastroenteritis; Inflammatory Bowel Diseases; Crohn Disease; Sphingosine 1 Phosphate Receptor Modulators; Immunosuppressive Agents; Immunologic Factors; Physiological Effects of Drugs; Molecular Mechanisms of Pharmacological Action; ozanimod
• Other Study ID Numbers: RPC01-3203; U1111-1203-8002 (Registry Identifier: WHO); 2023-510426-33 (Registry Identifier: EU Trial Number)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: Yes
• Studies a U.S. FDA-regulated device product: No