Search clinical trials for: Nasal Challenge

Total 5562 results

VistaGen Therapeutics, Inc.

Recruiting

Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-3) (PALISADE-3)

Social Anxiety Disorder

United States
National Jewish Health

Not yet recruiting

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma (Nasal-LPS)

Asthma | Asthma; Eosinophilic

United States
Karolinska Institutet

Recruiting

Nasal Allergen Challenge Test as a Method to Detect Clinical Reactivity Against Birch Pollen (NAC)

Allergic Rhinitis Due to Pollen

Sweden
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Nasal Immune Challenge Study

Asthma | Nasal Allergy | Innate Inflammatory Response

United Kingdom
Humanitas Clinical and Research Center
Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva

Recruiting

HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery (HISTAP)

Blood Pressure | Complication,Postoperative | Intraoperative Hypotension

Italy
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

HDM and Silver Birch NAC Standardisation

Allergic Rhinitis

United Kingdom
Medical University of Vienna

Recruiting

Contribution of Nasal IgE Production to the Boost of Systemic Allergen-specific IgE Upon Nasal Allergen Contact

Allergy

Austria
Bausch & Lomb Incorporated

Completed

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Allergic Conjunctivitis.

Allergic Conjunctivitis

United States
Vanderbilt University Medical Center
University of Oklahoma

Enrolling by invitation

Autoimmune Basis for Postural Tachycardia Syndrome

Cardiovascular Diseases | Arrhythmias, Cardiac | Autonomic Nervous System Diseases | Primary Dysautonomias | Tachycardia | Orthostatic Intolerance | Postural Tachycardia Syndrome | Postural Orthostatic Tachycardia Syndrome

United States
Imperial College London
GlaxoSmithKline

Completed

Nasal LPS Challenge in Healthy Volunteers

Healthy

United Kingdom
Imperial College London
Novartis Pharmaceuticals

Completed

Repeat Nasal Allergen Challenge

Hayfever

United Kingdom
Imperial College London
Millennium Pharmaceuticals, Inc.

Completed

Cigarette Smoke Nasal and Whole Blood Challenge in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Lung Diseases, Obstructive

United Kingdom
VistaGen Therapeutics, Inc.

Terminated

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge - 2 (Palisade-2)

Social Anxiety Disorder

United States
National Institute of Allergy and Infectious Diseases...
Regeneron Pharmaceuticals; PPD; Rho Federal Systems Division, Inc.; ALK-Abelló A/S and other collaborators

Active, not recruiting

Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction (GRADUATE)

Grass Pollen Allergy | Allergic Rhinoconjunctivitis

United Kingdom
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Inner-City Asthma Consortium

Completed

Cockroach Immunotherapy in Children and Adolescents (CRITICAL)

Persistent Asthma

United States
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prematurity-Related Ventilatory Control (PreVent)

Respiratory Control in Premature Infants

United States
VistaGen Therapeutics, Inc.

Completed

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge (Palisade-1)

Social Anxiety Disorder

United States
Imperial College London

Completed

Development of Human Nasal Challenge Models With Microbial Constituents and Grass Pollen

Asthma | Latent Tuberculosis | Allergic Rhinitis

United Kingdom
Imperial College London

Completed

Standardising Nasal Allergen Challenge in Adult With Hay Fever

Allergic Rhinitis

United Kingdom
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers. (Mitey Nose)

Healthy Participants | Tobacco Smokers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model (Kitty Nose)

Tobacco Smoking | Healthy Participants | E-cigarette Smokers

United States
Marinomed Biotech AG

Completed

Demonstration of a Decongestant Effect of "Coldamaris Akut" Compared to Saline Nasal Spray.

Allergic Rhinitis | Allergic Rhinoconjunctivitis

Austria
Marinomed Biotech AG

Completed

Demonstration of an Anti-allergic Effect in Subjects Treated With Callergin Nasal Spray in Comparison to Untreated Subjects and Subjects Treated With Vis Alpin® Alpensalz Nasal Spray, All Suffering From Grass Pollen Induced Rhinitis/Rhinoconjunctivitis

Allergic Rhinitis | Allergic Rhinoconjunctivitis

Austria
Bausch & Lomb Incorporated

Completed

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Acute Allergic Conjunctivitis.

Allergic Conjunctivitis

United States
Marinomed Biotech AG

Completed

Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray

Allergic Rhinitis | Allergic Conjunctivitis | Hayfever

Austria
Karolinska Institutet

Terminated

Goal Directed Haemodynamic Treatment for Patients With Proximal Femoral Fracture (GDHT)

Femoral Fracture

Sweden
Mitchell Grayson
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Leukotriene Antagonism in Recruitment of CD49d Expressing Neutrophils in Atopic Subjects

Nasal Allergy

United States
Hospital Universitari Vall d'Hebron Research Institute

Completed

Fluid Responsiveness in HFNC Patients (HIDRATE)

Sepsis | Shock, Septic | Respiratory Insufficiency

Spain
Brian J Lipworth

Completed

To Evaluate Adenosine Monophosphate and Allergen Challenge in Allergic Rhinitis

Allergic Rhinitis

United Kingdom
Laval University
AllerGen NCE Inc.

Completed

Nasal Allergen Challenge in Rhinitic Subjects

Asthma | Allergic Rhinitis

Canada
National Institute of Allergy and Infectious Diseases...
Inner-City Asthma Consortium

Completed

Cockroach Nasal Allergen Challenge Pilot

Asthma | Cockroach Hypersensitivity

United States
Gail Gauvreau

Unknown

Nasal Allergen Challenge - Reproducibility of Biomarkers and Effect of Topical Steroid Treatment (NACHO)

Allergic Asthma

Canada
GlaxoSmithKline

Completed

Follow-up Study to Investigate the Effect of GSK2245035 on Nasal Allergic Reactivity in Subjects Completing Treatment in Study TL7116958

Asthma and Rhinitis

Canada
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Cat Pilot Study - Environmental Exposure Chamber (EEC) vs. Nasal Allergen Challenge (NAC)

Hypersensitivity, Immediate

Canada
Kimberly-Clark Corporation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); NIZO Food...

Completed

Rudolph: Nasal Microbiota With Red and Sore Nose

Dermatitis

Netherlands
Haukeland University Hospital

Completed

Nasal Provocation Testing in Occupational Rhinitis (NPT)

Allergic Rhinitis (Disorder)

Norway
University of North Carolina, Chapel Hill
National Institutes of Health (NIH)

Withdrawn

Evaluation of a Nasal Allergen Challenge Procedure Using Dust Mite Extract (Dusty)

Healthy | Asthma | Dermatophagoides Farinae Allergy
University of Chicago

Terminated

Effect of Nasaleze on Nasal Challenge With Allergen

Allergic Rhinitis

United States
Universitair Ziekenhuis Brussel

Completed

The Challenge of Obtaining Qualitative Bacterial Cultures in Non-expectorating Cystic Fibrosis Patients

Cystic Fibrosis
University of Chicago

Unknown

Evaluating Factors Involved in Dymista's Superior Clinical Efficacy to Fluticasone Propionate in the Treatment of Seasonal Allergic Rhinitis

Allergic Rhinitis

United States
Janssen Research & Development, LLC

Terminated

Study to Examine the Cytokine Levels, Gene Expression and Safety of a Single Nasal Dose of JNJ-43260295, in Healthy Participants, and Atopic Participants With Mild to Mild-Persistent Asthma

Healthy | Asthma

United States
ORA, Inc.

Completed

Study Evaluating Nasal Symptoms Induced by a Nasal Allergen Challenge (NAC) To House Dust Mite Allergen

Allergic Rhinitis

United States
Merck Sharp & Dohme LLC

Completed

A Study on the Effects of a Single Dose of Prednisone on Biomarkers of Allergen Responses in Asthmatics (MK-0000-175)

Asthma
National Institute of Allergy and Infectious Diseases...
Asthma and Allergic Diseases Cooperative Research Centers

Terminated

Human Rhinovirus Infection and Airway Remodeling Mediators

Asthma

Canada
Medicus Research, LLC

Completed

MSM Product on Attenuating Nasal Provocation With a Standardized Allergenic Challenge

Nasal Breathing
University of Chicago
GlaxoSmithKline

Completed

Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen

Allergic Rhinitis

United States
Boehringer Ingelheim

Completed

Randomized, Placebo Controlled, Crossover Study in an Environmental Challenge Chamber to Assess Safety & Efficacy of Three Oral Doses of BI 671800 Versus Fluticasone Propionate and Montelukast in Sensitive Seasonal Allergic Rhinitis Patients Out of Season

Asthma | Rhinitis, Allergic, Seasonal

Germany
Pfizer

Completed

A Study to Test a New Decongestant in Patients With Allergic Rhinitis Following a Nasal Allergen Challenge

Allergic Rhinitis

United States
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); Genentech, Inc.

Completed

The Effects of Omalizumab (Anti-IgE) on the Late-phase Response to Nasal Allergen Challenge

Cat Allergy

United States
Medical College of Wisconsin
Merck Sharp & Dohme LLC

Completed

Innate Immunity and the Allergic Response

Nasal Allergies

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