Search clinical trials for: Opioid-induced hyperalgesia (OIH)

Total 241 results

Yonsei University

Completed

Effect of Nefopam on Remifentanil Induced Postoperative Hyperalgesia

Patients Undergoing Laparoscopic Gastrectomy

Korea, Republic of
Pontificia Universidad Catolica de Chile

Unknown

Opioid Induced Hyperalgesia (OIH) Modulation With Propranolol

Hyperalgesia
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Active, not recruiting

Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance

Chronic Pain

United States
Centre for Probe Development and Commercialization
St. Joseph's Healthcare Hamilton; McMaster University

Completed

A Single Centre Open Label Comparison of [I-123]-Ortho-Iodohippuric Acid (OIH) With [Tc-99m]-Mercaptoacetyltriglycine (MAG3) for Assessment of Renal Tubular Function

Renal Function Impairment

Canada
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Active, not recruiting

Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)

Chronic Pain

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil (0813)

Hyperalgesia

United States
Tianjin Medical University General Hospital

Not yet recruiting

Comparison of Remifentanil-induced Postoperative Hyperalgesia Between Patients From Plain Area and Plateau Area

Pain, Postoperative | Anesthesia

China
Tianjin Medical University General Hospital

Completed

Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia

Pain | Anesthesia

China
University Hospital, Basel, Switzerland

Completed

Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults (CANAB II)

Hyperalgesia | Allodynia | Opioid-induced Hyperalgesia | Acute Nociceptive Pain

Switzerland
National Institute on Drug Abuse (NIDA)

Unknown

Hyperalgesia in Methadone Patients: Can it be Treated?

Opioid-induced Hyperalgesia

United States
Tianjin Medical University General Hospital

Completed

Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients

Pain | Anesthesia

China
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia

Pain | Inflammatory Response | Hyperalgesia

Brazil
Oslo University Hospital

Completed

Opioid-induced Hyperalgesia After Remifentanil Infusion

Hyperalgesia

Norway
National Institute of General Medical Sciences...

Completed

Opiate-Induced Tolerance & Hyperalgesia in Pain Patients

Chronic Low Back Pain | Opioid-induced Hyperalgesia

United States
Cedars-Sinai Medical Center

Not yet recruiting

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

Dexmedetomidine | Adolescent Idiopathic Scoliosis | Remifentanil | Posterior Spinal Fusion | Multimodal Analgesia | Opioid Induced Hyperalgesia
University of Pittsburgh

Recruiting

Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks (OMEGA)

Analgesia | Pain, Procedural | Pain, Chronic | Facet Joint Pain

United States
University Hospital, Basel, Switzerland

Recruiting

Boosting Open-Label Placebo Effects in Acute Induced Pain in Healthy Adults (BOLPAP)

Acute Pain

Switzerland
Centre Hospitalier Annecy Genevois

Recruiting

Response Profiles to High-concentration Capsaicin Desensitization in Patients With Peripheral Neuropathic Pain With or Without Allodynia: a Regional Multicenter Prospective Cohort (CAPSICAURA)

Peripheral Neuropathic Pain

France
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

Chronic Pain | Opioid-Related Disorders | Opioid Use Disorder | Opioid Dependence | Chronic Pancreatitis | Hyperalgesia | Chronic Pain Syndrome | ERCP | Pancreatic Surgery | Chronic Abdominal Pain

United States
Wake Forest University Health Sciences
HonorHealth Research Institute

Recruiting

Internet-delivered Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN)

CIPN - Chemotherapy-Induced Peripheral Neuropathy

United States
Universiteit Antwerpen
University Hospital, Antwerp; Fund for Scientific Research, Flanders, Belgium

Recruiting

Identifying Biomarkers for Chronic Pain After Breast Cancer Treatment. (sCANsens)

Chronic Pain | Neoplasm, Breast | Carcinoma Breast

Belgium
University of Crete
University Hospital of Crete

Recruiting

Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fibromyalgia

Fibromyalgia | Hyperalgesia | Acupuncture | Electroacupuncture

Greece
Second Affiliated Hospital, School of Medicine,...

Recruiting

Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery

Postoperative Hyperalgesia

China
Istanbul Aydın University
Istanbul University; Acibadem University

Recruiting

The Efficacy of Acupressure in Managing Opioid-induced Constipation

Opioid-induced Bowel Dysfunction | Constipation Drug Induced

Turkey
Chinese PLA General Hospital
First Affiliated Hospital, Sun Yat-Sen University; Shengjing Hospital; First... and other collaborators

Not yet recruiting

Safety and Efficacy Evaluation of S (+) - Ketamine in Adults

Postoperative Pain | Anesthesia | Adults
Lviv National Medical University

Recruiting

Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations (BBESPB)

Nutrition Disorders | Chronic Pain | Postoperative Pain | Anesthesia, Local | Postoperative Cognitive Dysfunction | Scoliosis | Coagulation Disorder | Acute Pain | Neuropathic Pain | Anesthesia | Postoperative Nausea and Vomiting | Ventilator-Induced Lung Injury | Intraoperative Complications | Hyperalgesia | Regional... and other conditions

Ukraine
University Hospital, Clermont-Ferrand
NEURO-DOL (UMR 1107 INSERM / UCA)

Recruiting

Trial Investigating the Characteristics of Knismesis - a Lever to Explore Allodynia in Neuropathic Pain (TICKLE)

Healthy

France
Hospices Civils de Lyon

Recruiting

Post-operative Analgesic Effect of Oral Nefopam (NefPO)

Postoperative Pain After a Total Knee Arthroplasty

France
Université Catholique de Louvain

Recruiting

Central Sensitisation and Postoperative Pain

Thoracotomy | Hyperalgesia | Electroencephalography | Central Sensitisation | Hyperalgesia, Secondary | Humans | Persistent Postsurgical Pain

Belgium
BioDelivery Sciences International
HealthCore, Inc.

Recruiting

Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain

Opioid-induced Constipation

United States
University of California, Irvine

Recruiting

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

Hyperalgesia

United States
Leiden University Medical Center

Completed

Combined Effect of Pregabalin and Oxycodone, and Lacosamide and Oxycodone, on Breathing (POLO)

Opioid-induced Respiratory Depression

Netherlands
New York State Psychiatric Institute
Alkermes, Inc.

Suspended

Repeated Cannabis Administration on Experimental Pain and Abuse Liability

Pain | Cannabis | Hyperalgesia | Tolerance

United States
University of Manitoba

Completed

Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy

Opioid Use | Pain, Chronic | Hyperalgesia | Opioids; Harmful Use

Canada
University of California, San Francisco

Completed

Pain Medicine for Wound Care Procedures

Nausea | Vomiting | Hallucinations | Hyperalgesia | Pain Intensity | Wound Care

United States, Puerto Rico
Chinese PLA General Hospital
Shanghai Children's Medical Center; Beijing Children's Hospital; Southern Medical... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of S (+) - Ketamine in Children

Delirium | Postoperative Pain | Analgesia | Children | Acute Pain | Depression, Anxiety | Hyperalgesia | S-ketamine | Esketamine

China
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
Rigshospitalet, Denmark
National Institute on Drug Abuse (NIDA); University of Kentucky

Completed

Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.

Pain | Hyperalgesia | Central Nervous System Sensitization

Denmark
Rigshospitalet, Denmark
Bispebjerg Hospital

Completed

Postoperative Opioid and Respiratory Depression in Opioid Naive and Chronic Opioid Patients

Medical Complication

Denmark
University of Cape Town
University of Michigan; Brigham and Women's Hospital; Fogarty International Center... and other collaborators

Completed

An Observational Study of Distress, Immune Function, and Pain in HIV.

Chronic Pain | HIV | Distress, Emotional | Central Sensitisation | Immune System and Related Disorders

South Africa
University Hospital, Basel, Switzerland

Completed

Electrical Intra-cutaneous Half-sine Stimulation for Optimized Preferential C-fiber Activation

Pain Perception | Secondary Hyperalgesia

Switzerland
Medical University of Graz

Completed

The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia

Pain, Acute | Pain, Chronic | Central Sensitisation | Neuroinflammatory Response

Austria
Wonkwang University Hospital

Completed

The Effect of Remimazolam on Opioid Induced Hyperalgesia

Hyperalgesia, Mechanical

Korea, Republic of
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone

Post Operative Pain | Hyperalgesia

Italy
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Suspended

Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans

Pain | Cannabis | Hyperalgesia | Tolerance

United States
Jazz Pharmaceuticals

Completed

A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia

Pain | Peripheral Neuropathy

United Kingdom
Jazz Pharmaceuticals

Completed

A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.

Pain | Peripheral Neuropathy

United Kingdom
Balgrist University Hospital

Completed

Differences in Pain Processing Between Men and Women

Central Sensitisation

Switzerland
The Second Affiliated Hospital of Chongqing Medical...

Completed

Effect of S-ketamine in Cesarean Section Combined Anesthesia

Postoperative Pain

China

Search clinical trials for: Opioid-induced hyperalgesia (OIH)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Sri Lanka

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations