Search clinical trials for: Piperacillin, Tazobactam Drug Combination

Total 260227 results

Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
Centre Hospitalier Universitaire Vaudois
Unisanté Centre universitaire de médecine générale et santé publique; FORCE...

Not yet recruiting

Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance (DAR-ARC)

Febrile Neutropenia

Switzerland
Scandinavian Critical Care Trials Group

Not yet recruiting

Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis (EMPRESS)

Sepsis | Septic Shock

Denmark
University Hospital, Rouen

Not yet recruiting

Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary Stent (FRENCH24 ANIS)

Pancreaticoduodenectomy | Antibiotherapy
Sunshine Coast Hospital and Health Service
The Prince Charles Hospital; Mater

Not yet recruiting

Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and Bronchiectasis (CERTAIN)

Bronchiectasis | Cystic Fibrosis | Pseudomonas Aeruginosa | Burkholderia Cepacia Infection
University Hospital, Ghent
Imec; Research Foundation Flanders

Not yet recruiting

Validation of Betalactam ML Prediction Models - TDMAide (TDMAide)

Infections

Belgium
Shandong University
Shandong Provincial Hospital; Qianfoshan Hospital; Jining Medical University; Yantai... and other collaborators

Recruiting

Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis. (PIP/TAZO)

Late-Onset Neonatal Sepsis

China
McMaster Children's Hospital

Not yet recruiting

Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA) (ALPACA)

Appendicitis Perforated
Case Comprehensive Cancer Center

Recruiting

eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF

Pancreatic Fistula

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit (PITAGORE)

Sepsis | Septic Shock

France
Policlinico Hospital
Pfizer

Recruiting

Nosocomial Infections in Patients With ARDS Treated With ECMO (INF-ECMO)

Acute Respiratory Distress Syndrome | Extracorporeal Membrane Oxygenation Complication | Nosocomial Infection

Italy
Karolinska University Hospital

Recruiting

Pharmacokinetics of Piperacillin and Meropenem in ICU Patients

Antibiotic Pharmacokinetics

Sweden
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

Meropenem-FL058 Phase 2 Study in the Treatment of Complicated Urinary Tract Infections

Acute Pyelonephritis | Complicated Urinary Tract Infection
The University of Queensland
Chinese University of Hong Kong; University of Malaya; The Alfred; Centre Hospitalier... and other collaborators

Recruiting

PNEUmonia DOSing in Critically Ill Patients (PNEUDOS) (PNEUDOS)

Pneumonia

Hong Kong, France, Belgium, Australia, Malaysia
Ospedale San Carlo Borromeo
Associazione Oncologica Milanese AmoLaVita ONLUS

Not yet recruiting

Antibiotics Continuous Infusion at Home (TAID)

Severe Bacterial Infections

Italy
Zealand University Hospital

Recruiting

Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis. (PIPA)

Complicated Appendicitis

Denmark
Weill Medical College of Cornell University
Merck Sharp & Dohme LLC

Recruiting

Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation

Pneumonia | Hematologic Malignancy | Pseudomonas Aeruginosa

United States
University Hospital, Bordeaux

Recruiting

Efficacy of Piperacillin-tazobactam as Empirical Antimicrobial Therapy for VAP Among ESBL-E Carriers. (PROBATAZO)

Enterobacteriaceae Infections

France
Hospital Universitari de Bellvitge
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Recruiting

Efficacy of Extended Infusion of β-lactam Antibiotics for the Treatment of Febrile Neutropenia in Hematologic Patients (BEATLE)

Febrile Neutropenia

Spain
Merck Sharp & Dohme LLC

Recruiting

Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)

Nosocomial Pneumonia

United States, Estonia, Greece, Spain, Ukraine, Chile, Russian Federation, Colombia, Mexico
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
University Hospital, Rouen

Recruiting

Population Pharmacokinetic Modeling to Optimize the Dosage of the Piperacillin / Tazobactam Combination in Patients With Sepsis in Intensive Care (OPT-TAZ)

Resuscitation Patients With Sepsis

France
Rambam Health Care Campus
Canadian Institutes of Health Research (CIHR); Hadassah Medical Organization; McGill University Health Centre/Research Institute of the McGill University Health Centre and other collaborators

Recruiting

PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) (PETERPEN)

Bacteremia | Enterobacteriaceae Infections | Beta Lactam Resistant Bacterial Infection

Israel, Canada
University Hospital, Toulouse

Recruiting

Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients With Ventilator Associated-pneumonia (CEFTOREA)

Ventilator-associated Pneumonia

France
Memorial Sloan Kettering Cancer Center

Recruiting

Choosing the Best Antibiotic to Protect Friendly Gut Bacteria During the Course of Stem Cell Transplant

Febrile Neutropenia | Intestinal Microbiome

United States
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
University Hospital, Ghent
University Hospital, Antwerp; Queen Fabiola Children's University Hospital,...

Recruiting

Antibiotic Dosing in Pediatric Intensive Care (ADIC)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin

Belgium
Rambam Health Care Campus
Hadassah Medical Organization; Rabin Medical Center; The Chaim Sheba Medical...

Suspended

PipEracillin/Tazobactam Versus mERoPENem for Treatment of AmpC Producing Blood Stream Infections (SPICE-M)

Bacteremia | Enterobacteriaceae Infections | Beta Lactam Resistant Bacterial Infection

Israel
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Phoenix Children's Hospital

Completed

Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis

Postoperative Infection | Perforated Appendicitis

United States
West Virginia University

Enrolling by invitation

Comparing Oral Versus Parenteral Antimicrobial Therapy (COPAT)

Skin and Soft Tissue Infection | Gastrointestinal Infection | Pulmonary Infection | Bone and Joint Infection | Endovascular Infection | Genitourinary Infection

United States
University of Florida
Food and Drug Administration (FDA)

Terminated

BL Infusion Trial:Beta-lactam Continuous Versus Intermittent Infusion and Associated Bacterial Resistance and Therapy Outcomes in Critically Ill Patients With Severe Pneumonia

Pneumonia

United States
University of Michigan

Completed

Optimal Care of Complicated Appendicitis

Appendicitis | Complicated Appendicitis | Perforated Appendicitis | Ruptured Appendicitis

United States
Hospital Universitari de Bellvitge
Baxter Healthcare Corporation

Completed

Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®)

Sepsis | Acute Kidney Injury | Hemodiafiltration

Spain
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Hamad Medical Corporation
Merck Sharp & Dohme LLC

Withdrawn

CEFtolozane-Tazobactam for the Empiric Anti-bacterial Treatment of Neutropenic Fever in Hematology Patients (CEF-10)

Hematologic Cancer | Neutropenia, Febrile

Qatar
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Massachusetts General Hospital; Fox Chase Cancer Center and other collaborators

Active, not recruiting

Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?

Pancreatic Cancer | Pancreatic Diseases | Pancreas Cancer

United States, Canada
Chronic Obstructive Pulmonary Disease Trial Network...
Center for Genomic Medicine, Rigshospitalet, Denmark

Terminated

Targeted AntiBiotics for Chronic Pulmonary Diseases (Target-ABC)

Respiratory Tract Infections | Bronchiectasis | Asthma | COPD | Pseudomonas Aeruginosa

Denmark
The University of Queensland

Completed

Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Response (MERINO II)

Bloodstream Infections

Singapore, Australia
Merck Sharp & Dohme LLC

Completed

MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)

Pyelonephritis | Complicated Urinary Tract Infection

United States, Mexico, Russian Federation, Turkey, Greece, Hungary, Poland, Romania, South Africa, Ukraine
Merck Sharp & Dohme LLC

Completed

MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)

Complicated Intra-Abdominal Infection

Brazil, Hungary, United States, Lithuania, Malaysia, Mexico, Romania, Russian Federation, South Africa, Spain, Turkey, Ukraine
Groupe Hospitalier Paris Saint Joseph

Completed

Multicenter Evaluation of the Susceptibility of Enterobacteriaceae and Pseudomonas Aeruginosa to Ceftolozane/Tazobactam Combination (GMC-9)

Antibiotic Resistant Strain

France
Sara Thønnings

Withdrawn

Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia

Bacteremia
Assistance Publique - Hôpitaux de Paris

Completed

Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock (SSS)

Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit

France
University Hospital, Bordeaux

Completed

Are Standard Dosing Regimens of Piperacillin-Tazobactam Suitable in Critically Ill Patients With Open Abdomen and Negative Pressure Wound Therapy? A Population Pharmacokinetic Study. (PK-LAP)

Critical Illness | Laparotomy | Piperacillin, Tazobactam Drug Combination

France
Merck Sharp & Dohme LLC

Completed

Ceftolozane/Tazobactam (MK-7625A) Plus Metronidazole Versus Meropenem for Participants With Complicated Intra-abdominal Infection (MK-7625A-015) (7625ACNPhase3)

Complicated Intra-abdominal Infections

China
Göteborg University
Vastra Gotaland Region

Completed

Acute Appendicitis: Active Observation With and Without Antibiotics

Appendicitis

Sweden
The University of Queensland
Merck Sharp & Dohme LLC

Withdrawn

Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (MERINO III)

Bacteremia Caused by Gram-Negative Bacteria

Spain, Australia, Singapore, Italy, Saudi Arabia
Fundacion GenesisCare
Hospital La Milagrosa; Hospital Vithas Valencia Consuelo

Suspended

Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 (ULTRA-COVID)

Pneumonia, Viral | Cytokine Storm

Spain

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