Search clinical trials for: Serotonin 4 (5-HT4) receptor

Total 42731 results

Suven Life Sciences Limited

Completed

A Study to Investigate the Effect of Food, Gender, and Age on the Pharmacokinetic Profile of SUVN-D4010 in Healthy Subjects

Cognitive Disorder

United States
California Institute of Renal Research

Recruiting

A Single Arm sTudy to Evaluate the Effectiveness of EndoAVF in a Pre-dialysis Population (STEP Study)

CKD Stage 4 | CKD Stage 5 | CKD Stage 3

United States
McGill University Health Centre/Research Institute...

Recruiting

Safety and Efficacy of Canagliflozin in Advanced CKD (SIP-AKiD)

ESRD | CKD Stage 4 | CKD Stage 5

Canada
Hospices Civils de Lyon

Recruiting

Exploratory Study of the Expression of the Serotonergic 5-HT4 Receptor in Parkinson's Disease (PARK 5-HT4)

Parkinson Disease

France
Novartis

Completed

An Evaluation of the Efficacy and Safety of Tegaserod 6 mg Bid Given Orally to Chinese Patients With Chronic Constipation

Constipation

Switzerland
University of Oxford

Completed

Effects of Acute Prucalopride Administration in Healthy Volunteers

Depressive Disorder | Depression | Mood Disorders | Molecular Mechanisms of Pharmacological Action | Mental Disorder | Cognition | Antidepressive Agents

United Kingdom
Suven Life Sciences Limited

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-D4010 in Healthy Subjects

Cognitive Disorders

United States
Rigshospitalet, Denmark

Recruiting

The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling

Major Depressive Disorder | Sexual Behavior | Mood Change | Mood Disturbance | Affect Altered | Affect Blunted | Drug Mechanism

Denmark
Virginia Commonwealth University
Michael J. Fox Foundation for Parkinson's Research; RaQualia Pharma Inc.

Completed

RQ-00000010 for Gastroparesis and Constipation in Parkinson's Disease (RQ-10)

Parkinson's Disease | Constipation | Gastroparesis

United States
University of Oxford

Completed

Effects of Seven Day Prucalopride Administration in Healthy Volunteers

Mental Disorders | Depressive Disorder | Depression | Mood Disorders | Molecular Mechanisms of Pharmacological Action | Cognition | Antidepressive Agents

United Kingdom
American College of Radiology Imaging Network
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Unknown

DCE-MRI and DWI for Detection and Diagnosis of Breast Cancer (ACRIN6702)

Breast Cancer | BIRADS 3 | BIRADS 4 | BIRADS 5

United States
Guang'anmen Hospital of China Academy of Chinese...
Ministry of Science and Technology of the People´s Republic of China

Completed

Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial

Constipation
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Completed

Omicron BA.4/5-Delta Strain Recombinant Novel Coronavirus Protein Vaccine (CHO Cells)

Coronavirus

China
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Not yet recruiting

Clinical Study of Omicron BA.4/5-Delta Strain Recombinant Novel Coronavirus Protein Vaccine (CHO Cells)

Coronavirus
Novartis
Novartis Vaccines

Completed

Second Extension Study to Evaluate Safety and Tolerability of Influenza Vaccines in Adults and Elderly, and to Evaluate Immunogenicity and Concomitant Vaccination With Pneumococcal Vaccine in a Subgroup

Influenza

Poland
RWTH Aachen University

Unknown

Evaluation of the High-resolution, Contrast Enhanced Low-dose Breast-CT

BI-RADS 4 | BI-RADS 5 | BI-RADS 6 | High Risk of Breast Cancer Which Indicates a Mamma-MRI
Sumitomo Pharma Co., Ltd.

Completed

A Phase III Study of SM-13496 in Patients With Bipolar I Depression.

Bipolar Depression

Lithuania, Malaysia, Russian Federation, Slovakia, Ukraine, Japan, Philippines, Taiwan
Zeno Alpha Inc.

Completed

A Study of ZN-c5 and Abemaciclib in Participants With Breast Cancer

Breast Cancer

United States, Poland
McGill University Health Centre/Research Institute...
Heart and Stroke Foundation of Canada

Not yet recruiting

Canagliflozin in Advanced Renal Disease With MRI Endpoints (CARe-MRI)

ESRD, CKD Stage 4, CKD Stage 5
Quoin Pharmaceuticals

Recruiting

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome

United States
Movetis

Completed

Trial to Evaluate the Efficacy and Safety of R093877 in Patients With Chronic Idiopathic Constipation

Constipation
Ju Seok Ryu

Completed

The Effect of Botulinum Toxin Injection at Hip Adductor Muscles in Patients With Spastic Cerebral Palsy, Pilot Study

Cerebral Palsy

Korea, Republic of
Shire

Completed

Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Czechia, Germany, Latvia, Poland, Romania
Theravance Biopharma

Completed

Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial)

Chronic Constipation

United States
Kortuc, Inc.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy of KRC-01

Cervical Cancer

India, Thailand, United Kingdom
Bitop AG

Active, not recruiting

Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma. (EIL-AST)

Asthma

Poland
Astellas Pharma Inc

Completed

Comparative Trial of Micafungin Versus Fluconazole for Treating Esophageal Candidiasis

Candidiasis, Oral

South Africa, Brazil, Peru
National University, Singapore

Unknown

Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis Chronic Kidney Disease (CKD) Patients

Chronic Kidney Disease Stage 5 | Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 4

Singapore
Therapeutics, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of UHE-103 Cream in Subjects With Tinea Cruris and/or Tinea Pedis

Tinea Pedis | Tinea Cruris

United States
Eurocine Vaccines AB

Completed

Study to Assess the Safety, Tolerability and Immune Response Following Vaccination With Immunose™ FLU in Older Adults

Influenza

Sweden
Astellas Pharma Inc

Completed

Single and Multiple Dosing Study in Hemodialysis Patients With Hyperphosphatemia in Japan

Chronic Kidney Disease | Hyperphosphatemia Undergoing Hemodialysis

Japan
Astellas Pharma Inc

Completed

Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis

Candidiasis, Oral

Argentina, South Africa, Brazil, Peru
Solvay Pharmaceuticals

Terminated

Effect of Omacor on Triglycerides in HIV Infected Subjects

Hyper-Triglyceridemia

Germany, United Kingdom
Quoin Pharmaceuticals

Recruiting

Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome

United States
Philip Morris Products S.A.

Completed

Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting and 85 Days in an Ambulatory Setting

Smoking

Japan
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
Zydus Lifesciences Limited

Completed

Desidustat in the Treatment of Anemia in CKD (DREAM-ND)

Anemia | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 4

India
Universiti Putra Malaysia

Recruiting

Validation and Evaluation of a Newly Developed Mobile Diet App

Chronic Kidney Diseases | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease stage4 | Chronic Kidney Disease stage3 | Chronic Kidney Disease Requiring Chronic Dialysis

Malaysia
University Hospital, Strasbourg, France

Completed

Muscle Blood Flow During Exercise

Skeletal Muscle Blood Flow

France
Gilead Sciences

Completed

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 4 or 5 HCV Infection

Chronic Genotype 4 HCV | Chronic Genotype 5 HCV

France
Sun Yat-sen University

Completed

Sutures in Orbital Implants in Retinoblastoma Patients

Surgery--Complications | Retinoblastoma Bilateral
PBB Entrepreneur Ltd.

Completed

Efficacy and Tolerability of Topical Rossoseq™ Compared to Vehicle in Rosacea Subtype 1 (Erythematotelangiectatic)

Rosacea Subtype 1 (Erythematotelangiectatic)

Germany
BioNTech SE
Pfizer

Completed

A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals

COVID-19 | SARS-CoV-2 Infection

United States
University of Utah
Novartis

Withdrawn

BKM120 in Advanced, Metastatic, or Recurrent Endometrial Cancers (BKM120)

Endometrial Cancer

United States
Centre Hospitalier le Mans
Le Mans Universite

Withdrawn

Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis. (PIONNIER)

Fatigue | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease stage3 | Chronic Kidney Failure | Chronic Kidney Disease, Stage 4 (Severe)
Stanford University

Active, not recruiting

Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

Thyroid Cancer | Anaplastic Thyroid Cancer | Undifferentiated Thyroid Cancer

United States
Beijing Chao Yang Hospital

Recruiting

Efficacy of Intermittent Fasting on Metabolic Disease

Individuals With Metabolic Disease

China
Catharina Ziekenhuis Eindhoven

Terminated

Exercise Therapy With Risk Factor Management and Life Style Coaching After Vascular Intervention for Patients With Peripheral Arterial Disease (PEARL)

Peripheral Arterial Disease, Rutherford 4 and 5 With Possibility to Improve Vascularization

Netherlands
Ju Seok Ryu

Recruiting

Multidimensional Approach in Patients With Severe Cerebral Palsy, Prospective Cohort(MAPCP Cohort)-Offline

Cerebral Palsy, Spastic

Korea, Republic of
Cumhuriyet University
Scientific and Technological Research Council of Turkey (TUBITAK)

Completed

Examination of the Relationship Between Weight Gain During Pregnancy and Sfrp-5, Netrin-4 and Resistin Concentrations

Excessive Weight Gain During Pregnancy

Turkey

Search clinical trials for: Serotonin 4 (5-HT4) receptor

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