Search clinical trials for: The next generation of high-throughput gene sequencing (NGS)

Total 467772 results

Yizhuo Zhang

Recruiting

Clinical Value of Next Generation Sequencing in Chinese Childhood Solid Tumors

Pediatric, Solid Tumors, NGS

China
Chang Gung Memorial Hospital

Recruiting

Investigation and Diagnosis of the Chromosome Variation in Donated/Abandoned Blastocyst

Recurrent Miscarriage | Chromosome Translocation | Genetic Disorders in Pregnancy

Taiwan
National Cancer Institute (NCI)

Recruiting

A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...

Acute Lymphoblastic Leukemia | B-All

United States
The Belgian Society of Medical Oncology
Roche Pharma AG; Foundation Medicine; Sciensano

Recruiting

A Study to Examine the Value of Broad Agnostic Next Generation Sequencing (NGS) Panel Testing Versus Reimbursed Organ-directed NGS: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Center

Metastatic Cancer | Local Tumor Invasion

Belgium
Shanghai Chest Hospital
Geneplus-Beijing Co. Ltd.; Guangzhou Burning Rock Medical Examination Institute... and other collaborators

Unknown

A Prospective Study to Evaluate the Consistency of Next-Generation Sequencing(NGS)-Panels by Using Malignant Hydrothorax Form NSCLC

NSCLC | Malignant Hydrothorax

China
A2 Biotherapeutics Inc.
Tempus AI

Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing (BASECAMP-1)

Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Neoplasms | Ovarian Cancer | NSCLC | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Pancreas Cancer | Ovarian Carcinoma | Solid Tumor, Adult | CRC | Mesothelioma; Lung

United States
Rennes University Hospital

Completed

Retrospective Study Using Next Generation Sequencing (NGS) on Biological Samples to Improve Genetic Counseling for Patients With Previously Explored Craniofacial Midline Defects. (EXOMEDIANE)

Holoprosencephaly

France
China Medical University, China

Unknown

Sensitivity and Specificity of NGS in Detecting bMSI in Patients With Gastric, Duodenal and Small Intestinal Cancer

Gastrointestinal Cancer

China
Yunfeng Hou

Not yet recruiting

The Value of mNGS in Diagnosis of Pulmonary Infection

Pulmonary Infection
Fudan University
Southern Medical University, China

Completed

The Implication of Plasma ctDNA Methylation Haplotypes in Detecting Colorectal Cancer and Adenomas

Colorectal Cancer | Adenoma

China
Imperial College London Diabetes Centre

Unknown

Genetic Causes of Hypercholesterolaemia in the Emirati Population

Familial Hypercholesterolemia

United Arab Emirates
Fujian Cancer Hospital

Unknown

Next-generation Sequencing of Small Cell Lung Cancer to Identify Susceptibility Gene and to Assess Treatment

SCLC
Xianmin Song, MD

Recruiting

Next Generation Sequencing（NGS）Monitors Minimal Residual Disease（MRD）in Allo-PBSCT Patients

NGS Monitor MRD

China
Imperial College London Diabetes Centre

Unknown

Application of UCPCR as a Testing Tool for Identification of MODY Patients in the UAE

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Maturity-onset Diabetes of the Young

United Arab Emirates
National Cancer Institute, Naples

Recruiting

Molecular Data and Their Correlations With Clinical Outcomes in Gynecological Cancer Patients. (GYNGER)

Gynecologic Cancer

Italy
Imperial College London Diabetes Centre

Unknown

Delineation of Novel Monogenic Disorders in the United Arab Emirates Population

Mendelian Disorders | Genetic Disorder | Novel Mutation | Hereditary Disorder | De Novo Mutation | Inherited Disease | Single-Gene Defects

United Arab Emirates
AnchorDx Medical Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Active, not recruiting

Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules

Pulmonary Nodules

China
Jagiellonian University

Recruiting

Endometriosis and Peritoneal Dysbiosis

Endometriosis | Infertility Unexplained

Poland
Na Homolce Hospital
Czech Academy of Sciences

Completed

miRNA in Patients With Thoracic, Abdominal and Intracranial Aneurysms (miRNA)

Vascular Aneurysm

Czechia
The First Hospital of Jilin University

Not yet recruiting

Performance Study of Targeted Sequencing Technology for VAP

VAP - Ventilator Associated Pneumonia
University Hospital Tuebingen
Charite University, Berlin, Germany; RWTH Aachen University; Medical University...

Not yet recruiting

Initiative for Clinical Long-read Sequencing (IonGER)

Genetic Predisposition

Germany
University Health Network, Toronto
Women's College Hospital; Jewish General Hospital; IWK Health Centre; British Columbia... and other collaborators

Recruiting

Cell-free DNA in Hereditary And High-Risk Malignancies (CHARM)

Hereditary Cancer Syndrome

Canada
Fudan University

Unknown

Use of Plasma ctDNA Methylation Haplotypes in Detecting Local Residual or Lymph Node Metastasis

Colorectal Cancer | Lymph Node Metastases

China
University Hospital Tuebingen

Recruiting

Diagnostic Research in Patients With Rare Diseases - Solving the Unsolved Rare Diseases (DiRiP-RD)

Rare Diseases | Genetic Predisposition

Germany
University Hospital Tuebingen

Recruiting

Genetic Causes of Discrepant Clinic in Monogenic Twins (DISCO-TWIN)

Genetic Predisposition to Disease | Rare Diseases

Germany
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YongLin Healthcare Foundation

Recruiting

Research on the Heterogeneity of Taiwanese Breast Cancer Patients by Next Generation Sequencing (NGS) Tools

Breast Cancer | Next Generation Sequencing (NGS)

Taiwan
Reproductive & Genetic Hospital of CITIC-Xiangya

Terminated

A Study of Preimplantation Genetic Screening With Next Generation Sequencing Technology on Advanced Age Women

Infertility

China
Children's Hospital of Chongqing Medical University
The First Hospital of Jilin University; Xuzhou Maternity and Child Health Care... and other collaborators

Completed

The Pilot Study of High-throughput Sequencing in Neonatal Birth Defects

Genetic Diseases | Birth Defect | Congenital Malformation | Multiple Malformation | Newborn; Fit

China
PETHEMA Foundation

Completed

Diagnostic Platform to Perform Centralized and Standardized Rapid Molecular Diagnosis by Next Generation Sequencing (NGS) in Patients Diagnosed With Acute Myeloid Leukemia.

Acute Myeloid Leukemia

Spain
Imperial College London Diabetes Centre

Unknown

Genetic Causes of Gestational Diabetes in the Emirati Population

Gestational Diabetes | Maturity-onset Diabetes of the Young | GDM | MODY

United Arab Emirates
Addario Lung Cancer Medical Institute
Dana-Farber Cancer Institute

Active, not recruiting

Study of Plasma NGS for Assessment, Characterization, Evaluation of Patients With ALK Resistance (SPACEWALK)

Non-Small Cell Lung Cancer

United States
MicroGenDX

Recruiting

Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms

Interstitial Cystitis | Bladder Pain Syndrome

United States
Huashan Hospital

Not yet recruiting

NGS-Guided(G) Regimens(R) of Anti-tuberculosis(A) Drugs for the Control(C) and Eradication(E) of MDR-TB (GRACE-TB)

Multidrug Resistant Tuberculosis

China
Institut National de la Santé Et de la Recherche...
Institut Bergonié; Plateforme labellisée Inca - Institut Bergonié, Bordeaux; Plateforme... and other collaborators

Completed

Molecular Profiling to Improve Outcome of Patients in Cancer. A Pilot Study (MULTIPLI-0)

Soft Tissue Sarcoma | Colorectal Carcinoma

France
Peking Union Medical College

Unknown

Clinical Value of Next Generation Sequencing in Endocrine Therapy for Advanced Hormone Receptor Positive/HER-2 Negative Breast Cancer

Breast Neoplasm Female | Mutation | Therapeutics

China
Institut de Médecine et d'Epidémiologie Appliquée...
ANRS, Emerging Infectious Diseases

Recruiting

Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST) (NGS-IST)

Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Neisseria Gonorrhoeae Infection | Sexually Transmitted Infections (Not HIV or Hepatitis)

France
University Hospital Tuebingen

Recruiting

Mitochondrial Diseases - Long-read Genome and Transcriptome Sequencing in Cases Unresolved After Short-read Genomics

Rare Diseases | Genetic Predisposition

Germany
Affiliated Hospital of Nantong University
Second Affiliated Hospital of Nantong University; Children's Hospital of Fudan... and other collaborators

Recruiting

Clinical Precise Diagnosis and Treatment in the Kawasaki Disease

Kawasaki Disease

China
Fujian Cancer Hospital

Unknown

Next-generation Sequencing in Gastrointestinal Cancer

Gastrointestinal Cancer

China
MicroGenDX

Recruiting

Next Generation Sequencing Versus Traditional Cultures for Clinically Infected Penile Implants: Impact of Culture Identification on Outcomes

Infections | Penile Implantation

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Cost of Cancer Diagnosis Using Next-generation Sequencing Targeted Gene Panels in Routine Practice

Cancer
Centre Henri Becquerel
U918 ( Inserm unit)

Completed

Assessment of the Minimal Residual Disease in DLBCL From Cell-free Circulating DNA by NGS (LymphoSeq)

Non Hodgkin Lymphoma

France
Hellenic Cooperative Oncology Group

Completed

Pathogenic Variants in Homologous Recombination Repair Genes in Patients With Epithelial Ovarian Cancer (PaVaClO)

Epithelial Ovarian Cancer
Chinese Anti-Cancer Association

Unknown

The Registration Program of BRCA1/2 Gene (RCA)

Breast Cancer

China
University Hospital Tuebingen

Completed

NGS Diagnostic in COVID-19 Hosts - Genetic Cause Relating to the Course of Disease Progression (COVID-19 NGS)

COVID-19

Germany
Herlev Hospital
Rigshospitalet, Denmark

Completed

Utility of EUS-guided Microbiopsies in Pancreatic Cystic Lesions

Pancreatic Adenocarcinoma | Pancreatic Cyst | IPMN | Mucinous Cyst

Denmark
Rothman Institute Orthopaedics

Unknown

NGS for Non-unions

Nonunion of Fracture

United States
University Hospital, Essen
Noscendo GmbH, Germany; Health Economics and Health Care Management, Bielefeld... and other collaborators

Recruiting

Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics (DigiSep)

Sepsis | Septic Shock

Germany
Munich Leukemia Laboratory
Illumina, Inc.

Recruiting

Solving Riddles Through Sequencing (SIRIUS)

Leukemia | Rare Diseases | Refractory Lymphoma | Hematologic Malignancy | Refractory Leukemia | Unknown Primary Tumors

Germany
Hellenic Institute for the Study of Sepsis
The BioArte

Completed

NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification (BIOARTE)

Pneumonia | Bacteremia | Acute Pyelonephritis | Biliary Tract Infection

Greece

Search clinical trials for: The next generation of high-throughput gene sequencing (NGS)

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