Search clinical trials for: active metabolite

Total 8172 results

Chiesi Farmaceutici S.p.A.
SGS S.A.

Recruiting

Clinical Study to Evaluate the Safety, Tolerability and the Concentration of the BDP (Beclomethasone Dipropionate), Active Metabolite of BDP, FF( Formoterol Fumarate) and GB (Glycopyrronium Bromide), After Inhalation of CHF 5993 at Two Different Doses and QVAR®

Asthma

Belgium
National Research Centre for the Working Environment...
Rigshospitalet, Denmark; University of Copenhagen; University Hospital Bispebjerg...

Recruiting

Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Training (BIOBRAND3)

Oxidative Stress | Heart Rate Variability | Heat Stress | Reactive Hyperemia | Micro RNA | DNA Strand Breaks

Denmark
Aarhus University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Recruiting

TDM for Optimized Outcome in Patients With mRCC.

Kidney Cancer | Renal Cell Carcinoma Metastatic | Drug Toxicity | Drug Side Effect | Drug Mechanism

Denmark
Memorial Sloan Kettering Cancer Center
Samus Therapeutics

Active, not recruiting

PET Imaging of Cancer Patients Using 124I-PUH71: A Pilot Study

Non-Hodgkin's Lymphoma | Myeloma | Active Solid Malignancy

United States
University of Florida
Scott R. MacKenzie Foundation

Completed

Impact of Chronic Kidney Disease on Clopidogrel Effects in Diabetes Mellitus

Coronary Artery Disease (CAD) | Type 2 Diabetes Mellitus (T2DM) | Chronic Kidney Disease (CKD)

United States
Viriom

Completed

Study of Single Ascending Doses of Elsulfavirine to Evaluate the Safety, Tolerability, and Pharmacokinetics of Elsulfavirine and Its Active Metabolite VM-1500A in Healthy Subjects

HIV-1-infection

United States
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of Pharmacokinetics (PK) of Acalabrutinib and Its Active Metabolite (ACP-5862) When Administered Alone and With Moderate CYP3A4 Inhibitors Fluconazole or Isavuconazole in Healthy Adult Participants

Healthy Volunteers

United States
Emalex Biosciences Inc.
Syneos Health; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite

Drug Interaction

United States
AstraZeneca

Completed

PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4) (HESTIA4)

Sickle Cell Disease

Belgium, United Kingdom, Italy, Spain, Kenya, Lebanon
Celgene

Completed

Drug Interaction Study of the Effect on Cyclosporine on Ozanimod and Major Active Metabolites

Healthy Volunteers

United States
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Withdrawn

Pharmacokinetics of Antiplatelet Drugs in Diabetic pAtients (PANDDA)

Diabetes

Canada
Celgene

Completed

Extension Study to Further Evaluate the Safety, Pharmacodynamics and Pharmacokinetics of Ozanimod and Active Metabolites

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Pharmacokinetic Study on the Effect of LY2216684 on the Active Metabolite of Clopidogrel

Major Depressive Disorder

United States
Actelion

Completed

A Clinical Study to Assess the Effect of Clopidogrel on the Pharmacokinetics of Selexipag and Its Active Metabolite in Healthy Male Subjects

Healthy Subjects

Belgium
Collegium Medicum w Bydgoszczy

Completed

Which Platelet Function Test Best Reflects the In Vivo Plasma Concentrations of Ticagrelor and Its Active Metabolite? (HARMONIC)

Myocardial Infarction | Infarction | Ischemia | Pathologic Processes | Necrosis | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Vascular Diseases

Poland
Eisai Inc.

Completed

A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Administration of LUSEDRA to Lactating Women Undergoing a Needed Procedure

Lactating Women

United States
Asan Medical Center
Korea National Enterprise for Clinical Trials

Completed

In Vitro Interaction Between Ticagrelor and Its Active Metabolite and Their Effects on Salicylic Acid (In_vitro_PAT)

Cardiovascular Diseases

Korea, Republic of
I.R.C.C.S. Fondazione Santa Lucia

Not yet recruiting

REducing the Risk of COgnitive DEcline ad Dementia in Patients With Subjective Cognitive Decline Through an Immersive Virtual Reality and Telemedicine-based Multi-component Intervention: the SCD-ReCODED Study (SCD-ReCODED)

Subjective Cognitive Decline
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Study on the Mechanism of ZhenQiFuZheng in the Treatment of Allergic Rhinitis Based on Intestinal Flora and Metabolites

Rhinitis, Allergic
University of Ulster
Northern Health & Social Care Trust (NHSCT); Solvotrin Therapeutics - Active...

Not yet recruiting

Adiposity and Iron Requirements in Pregnancy (ADIPREG)

Iron Deficiency Anemia of Pregnancy

United Kingdom
University of Valencia

Recruiting

Differences and Changes in Lower Limb Muscle Activation and Ankle Stability in Different Blackboard Configurations

Electromyography

Spain
Dartmouth-Hitchcock Medical Center
Dartmouth College; University of Massachusetts, Worcester

Not yet recruiting

Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application (SONATA)

Epilepsy | Refractory Epilepsy | Music

United States
Universidad Católica San Antonio de Murcia

Not yet recruiting

Upper Limb Blood Flow Restriction in Handball Players

Sports Physical Therapy

Spain
University of Hail

Not yet recruiting

A Randomized Controlled Trial Comparing Controlled Active Motion and Early Passive Mobilization Protocols for Rehabilitation of Repaired Flexor Tendons in Zone II

Flexor Tendon Rupture

Saudi Arabia
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Preoxygenation for Tracheal Aspirations in Intensive Care (POXTRA)

ICU Patients Under Invasive Mechanical Ventilation

France
Koya Medical, Inc.

Recruiting

Clinical Study to Evaluate the Effectiveness and Health Economics of a Novel Portable Non-Pneumatic Active Compression Device (NPCD) for Lymphedema/Phlebolymphedema (GRANDE)

Lymphedema | Chronic Venous Insufficiency | Phlebolymphedema

United States
Hospital Italiano de Buenos Aires

Not yet recruiting

Mortality of MBL-producing Enterobacteriaceae Bacteremias With the Combined Use of Ceftazidime-avibactam and Aztreonam vs. Other Active Antibiotics. A Multicenter Target Trial Emulation.

Bacteremia
VA Office of Research and Development

Not yet recruiting

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Depression | Chronic Low Back Pain

United States
VA Palo Alto Health Care System
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Stanford University

Not yet recruiting

Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder

Drinking Behavior | Alcoholism | Alcohol Use Disorder | Alcohol Abuse | Drinking Problem

United States
United States Naval Medical Center, San Diego
Minneapolis Veterans Affairs Medical Center; United States Department of Defense and other collaborators

Not yet recruiting

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

Brain Injuries | Brain Injuries, Traumatic | Brain Concussion | Mild Cognitive Impairment | Memory Impairment | Mild Traumatic Brain Injury | Attention Impaired | Neurocognitive Dysfunction | Brain Trauma | Attention Concentration Difficulty | Post Concussive Symptoms

United States
Örebro University, Sweden
Region Örebro County

Recruiting

ReActivate: Physiotherapist Led Intervention for Adolescents With Pain and Psychological Distress.

Chronic Pain | Emotional Distress

Sweden
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms

Parkinson Disease

China
Novo Nordisk A/S

Not yet recruiting

Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease

Alcohol-related Liver Disease

Spain, Denmark, United States, Australia, Canada, Netherlands, Italy, Bulgaria, Czechia, Germany, Greece, France, Japan, Poland
Innovation Research & Training
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Study of an Online Program to Help Parents Talk With Their Tween Children About Health, Gender, Body-Image, and Relationships

Communication | Parent-Child Relations | Parenting

United States
University of Barcelona
University Ramon Llull; ICREA Academia; Institut de Neurociències de la Universitat... and other collaborators

Recruiting

Active Young, Healthy Mind. The YoungFitT Project (YoungFitT)

University Students

Spain
Median
Johannes Gutenberg University Mainz

Recruiting

Passive Microprocessor-controlled Knees vs. Active Microprocessor-controlled Knees After Transfemoral Amputation

Amputation

Germany
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis

Lupus Nephritis

China
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Sleep Disturbance | Long COVID | Long COVID-19
Universitaire Ziekenhuizen KU Leuven
CHU UCL Namur

Not yet recruiting

Recovery From Disability After Geriatric-home Rehabilitation Versus Standard of Care: Pilot Study (RECOVER@HOME)

Disability Physical

Belgium
Swedish Orphan Biovitrum

Recruiting

Assessment of Macrophage Activation syndromE in STill's Disease (AMETHYST)

Still's Disease, Adult-Onset | Macrophage Activation Syndrome | Stills Disease, Juvenile-Onset

United States, Canada, France, Germany, Italy, Netherlands, Spain
University of Maryland, Baltimore
The University of Texas Health Science Center, Houston

Not yet recruiting

Facilitating Neuroplastic Changes of Acute Stroke Survivors

Stroke
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol

Sleep Disturbance | Long COVID | Long COVID-19 | Hypersomnia
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Ablation of Focal Activation in Atrial Fibrillation (RETRO-AF)

Atrial Fibrillation | Arrhythmias, Cardiac | Arrhythmia | Atrial Fibrillation, Persistent | Cardiac Arrhythmia

United Kingdom
Freundeskreis Für Internationale Tuberkulosehilfe...

Not yet recruiting

Evaluation of CAD-based Triage for CXR Interpretation During TB Screening

Tuberculosis

Vietnam
Children's Oncology Group

Not yet recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor
Wuhan Union Hospital, China
ITabMed Co., Ltd.

Not yet recruiting

Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
VA Office of Research and Development

Not yet recruiting

Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

Alcohol Use Disorder

United States
Zydus Lifesciences Limited

Recruiting

A Study to Evaluate the Efficacy and Safety of ZYIL1 Oral Capsules for the Treatment of Patients With Mild to Moderately Active Ulcerative Colitis Resistant or Intolerant to Oral Aminosalicylates

Ulcerative Colitis

India
University of the Balearic Islands

Recruiting

Effectiveness of a Peer-led Intervention for Individuals With Major Depression. (SUPEERmood)

Depressive Disorder, Major

Spain
Institut Investigacio Sanitaria Pere Virgili

Not yet recruiting

Circulating Microvesicles Regulating Metabolic Homeostasis in Obesity After Caloric Restriction Programs (TREV)

Obesity

Search clinical trials for: active metabolite

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