Search clinical trials for: corneal disorders

Total 147393 results

Eye & ENT Hospital of Fudan University
Soochow University

Recruiting

Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis (ASOTARI)

Eye Diseases | Corneal Diseases | Sensation Disorders | Vision Disorders | Blindness | Infections, Bacterial | Bacterial Keratitis | Antibiotic-resistant Bacteria | Antisense Peptide Nucleic Acid | Antibacterial Therapy

China
AbbVie

Recruiting

An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
AbbVie

Recruiting

An Observational Study to Assess Optive MEGA-3 (OM3) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
Maastricht University Medical Center
Diabetes Fonds

Recruiting

The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes (PYRAMID)

Type 2 Diabetes | Neuropathy, Diabetic | Nephropathy, Diabetic | Microvascular Function | Retinopathy, Diabetic

Netherlands
Lumenis Be Ltd.

Recruiting

Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects With Dry Eye Disease

Dry Eye | Dry Eye Syndromes | Eyelid Diseases | Skin Laxity | Eyelid Movement Disorders

United States
University of Southern California

Recruiting

Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium

Corneal Endothelium

United States
Medical University of Vienna

Not yet recruiting

Corneal Findings in Patients Treated With Belantamab Mafodotin

Multiple Myeloma | Corneal Diseases | Corneal Cyst
CorNeat Vision Ltd.

Recruiting

Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness

Corneal Opacity | Corneal Disease | Corneal Injuries

France, Canada, Israel, Netherlands
Tufts Medical Center
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Prospective Study to Validate the Imaging Biomarker for NCP (R33)

Dry Eye Syndromes | Corneal Disease

United States
Hellenic Society of Hematology
GlaxoSmithKline

Not yet recruiting

A Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin in Combination With Daratumumab, Pomalidomide and Dexamethasone in Patients With Relapsed/ Refractory Multiple Myeloma Previously Treated With One Line Therapy Who Are Lenalidomide Refractory

Neoplasms | Multiple Myeloma | Neoplasms, Plasma Cell | Paraproteinemias | Blood Protein Disorders | Corneal Disease | Multiple Myeloma in Relapse | Gammopathy, Monoclonal | Haematologic Disease
Hellenic Society of Hematology
GlaxoSmithKline

Recruiting

A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple Myeloma

Neoplasms | Multiple Myeloma | Paraproteinemias | Blood Protein Disorders | Corneal Disease | Gammopathy, Monoclonal | Haematologic Disease | Neoplasm, Plasma Cell

Greece
Rambam Health Care Campus

Recruiting

Rapid Computerized Visual Acuity Test

Refractive Errors | Cataract | Vision Disorders | Retinal Disease | Corneal Disease

Israel
EL Romany Ophthalmics Factory

Not yet recruiting

Cyanocobalamin as Photosensitizing Agent

Keratoconus
Singapore National Eye Centre
Singapore Chung Hwa Medical Institution

Recruiting

Herbal Medication to Treat Dry Eye in Peri/ Post-menopausal Women

Dry Eye

Singapore
Hellenic Society of Hematology
GlaxoSmithKline

Recruiting

A Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin in Combination With Daratumumab, Lenalidomide and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Transplant Ineligible

Neoplasms | Multiple Myeloma | Neoplasms, Plasma Cell | Paraproteinemias | Blood Protein Disorders | Corneal Disease | Gammopathy, Monoclonal | Haematologic Disease

Greece
Indiana University

Recruiting

The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients

Ocular GVHD

United States
Center for Sight, Sacramento, CA

Not yet recruiting

Corneal Collagen Cross-Linking (CXL) Performed With "Epi-ON" Versus "Epi-OFF" in Eyes With Keratoconus and Other Corneal Ectatic Disorders

Keratoconus | Ectasia

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Recruiting

Diadenosine Polyphosphates and Mucin Associated With Ocular Surface Disorders

Dry Eye Syndromes | Graft Vs Host Disease | Superior Limbic Keratoconjunctivitis

Taiwan
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Rush Eye Associates

Recruiting

The Effects of Corneal Collagen Cross-linking

Corneal Ectasia Disorders Including Keratoconus

United States
Asociación para Evitar la Ceguera en México

Terminated

Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C

Refractive Disorders

Mexico
Alaska Blind Child Discovery

Completed

Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines (2WINbus)

Refractive Errors | Strabismus | Amblyopia | Development Delay

United States
NYU Langone Health
National Eye Institute (NEI)

Active, not recruiting

Novel Diagnostics With Optical Coherence Tomography: Imaging the Anterior Eye

Fuch's Dystrophy | Corneal Disorders | Prior Surgery

United States
Genzyme, a Sanofi Company

Active, not recruiting

A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2 (AMETHIST)

Tay-Sachs Disease | Sandhoff Disease

United States, Argentina, Czechia, Portugal, Russian Federation, Turkey, United Kingdom, Brazil, France, Germany, Italy, Japan, Spain
Umeå University
Glaukos Corporation

Active, not recruiting

Epi-on PiXL for the Treatment of Progressive Keratoconus.

Eye Diseases | Keratoconus | Corneal Crosslinking | Corneal Densitometry | Scheimpflug Photography | Corneal Disorder

Sweden
Laboratórios Baldacci S.A
Opera CRO, a TIGERMED Group Company

Completed

Performance and Tolerability of the Medical Device LACRIACT

Dry Eye | Photophobia | Contact Lens Acute Red Eye | Discomfort

Italy
GlaxoSmithKline

Terminated

Characterization of Corneal Epithelial Changes in Participants Treated With Belantamab Mafodotin

Multiple Myeloma

United States
Lentechs, LLC

Completed

Corneal Oxygen Uptake With Apioc Contact Lenses

Contact Lens-Induced Corneal Disorder of Both Eyes (Diagnosis)

United States
Tianjin Eye Hospital

Completed

The Characteristics of Backscattering With Depth in the Progression of Keratoconus

Elasticum, Incomplete Pseudoxanthoma

China
Vanderbilt University Medical Center
National Institute of Neurological Disorders and Stroke (NINDS); University... and other collaborators

Enrolling by invitation

POTS NET mRNA Functional Correlation With NET Activity

Postural Tachycardia Syndrome

United States
CorNeat Vision Ltd.

Terminated

First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness

Corneal Opacity | Corneal Disease | Corneal Injuries

France, United States, Canada, Netherlands, Israel
University of Texas Southwestern Medical Center

Active, not recruiting

Corneal Sensitivity in Patients With Sleep Apnea Syndrome

Sleep Apnea

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Corneal Toxicity in Patients Treated by Belantamab Mafodotin

Myeloma Multiple

France
Glia, LLC

Completed

Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel

Contact Lens Discomfort | Contact Lens-induced Corneal Disorder | Contact Lens Acute Red Eye | Contact Lens-induced Corneal Fluorescein Staining

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH) (BioHoFH)

Lipoprotein Lipase Deficiency | Inborn Error of Lipid Metabolism | Corneal Arcus

Germany, India, Sri Lanka
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Prospective Single-center Long-term Follow-up Study of a Series of Cases Previously Included in the QUALVIDON Study (QUALVIDON2)

Dry Eye | Neuropathic Pain

France
UMC Utrecht
Universitaire Ziekenhuizen KU Leuven; Maastricht University Medical Center; Carl...

Completed

The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation (ADVISE)

Vision Disorders | Fuchs Dystrophy | Bullous Keratopathy | Endothelial Corneal Dystrophy

Netherlands, Belgium
Centre Hospitalier Régional Metz-Thionville

Completed

Predictive Factors of Graft Detachment Following Dmek (PDF DMEKDETACH)

Pseudophakic Bullous Keratopathy | Fuchs' Endothelial Corneal Dystrophy | Descemet Membrane Endothelial Keratoplasty | Graft Detachment

France
Shanghai BDgene Co., Ltd.
Eye & ENT Hospital of Fudan University

Completed

Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral Keratitis

Cornea | Herpes Simplex Virus Infection | Viral Keratitis | Blindness Eye

China
Yifeng Yu

Completed

Dry Eye Under China's Dynamic COVID-zero Strategy

Dry Eye Symptoms

China
University of Faisalabad

Completed

Impact of Vitamin D3 Supplementation in Non-Sjogren Dry Eye Patients With Low Serum Vitamin D Level

Dry Eye Syndromes | Hypovitaminosis D

Pakistan
Heidelberg Engineering GmbH

Completed

Repeatability of Static & Dynamic Composite Confocal Microscopy for Assessment of the Corneal Nerve Fiber Plexus in Early Diabetic Polyneuropathy

Normal Eyes of Subjects Without Diabetes Mellitus | Subjects With Diabetes Mellitus Type 2 Without Coexisting DPN | Subjects With Diabetes Mellitus Type 2 With Coexisting Early to Moderate DPN
Peking University Third Hospital

Completed

Comparison of Ocular Surface Features in Patients With Diabetes and Dry Eye Syndrome

Diabetes Mellitus Type 2 | Dry Eye Syndrome

China
Optimal Acuity Corporation

Completed

Observational Study of Vision Improvement in Patients With Retinal Disorders

Age-related Macular Degeneration | Diabetic Macular Edema

Canada
Tanta University

Completed

Quality of Life Improvement in Dry Eye Patients After Intense Pulsed Light Therapy Compared to Punctal Plugs

Evaporative Dry Eye

Egypt
University Hospitals Cleveland Medical Center

Withdrawn

Correlation of Scheimpflug Densitometry Measurements of Corneal Haze With Disability Glare

Vision Disability

United States
Lawson Health Research Institute

Completed

Ocular Manifestations in Rheumatic Diseases

Uveitis | Macular Edema | Retinal Vein Occlusion | Retinitis | Orbital Diseases | Optic Neuritis | Keratoconjunctivitis Sicca | Conjunctivitis | Blindness | Xerophthalmia | Papilledema | Iridocyclitis | Retinal Artery Occlusion | Amaurosis Fugax | Scleritis | Eye Hemorrhage | Chorioretinitis | Choroid Hemorrhage
Seva Foundation
Queen's University, Belfast; Bharatpur Eye Hospital; Indian Institute of Public... and other collaborators

Completed

Improving the Follow up Rate for Pediatric Patients

Conjunctivitis | Strabismus | Amblyopia | Corneal Ulcer | Eye Injuries | CNLDO - Congenital Nasolacrimal Duct Obstruction

Nepal
Hospital Clinic of Barcelona

Completed

Risk Factors for AD-Associated Switch to Mania

Bipolar Disorder

Spain
University of Pennsylvania

Completed

Corneal Nerve Structure in Sjogren's

Vitamin D Deficiency | Sjogren's Syndrome

United States

Search clinical trials for: corneal disorders

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