Search clinical trials for: healthy volunteers, GMI-1271

Total 28260 results

GlycoMimetics Incorporated

Completed

Placebo-controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1271 in Healthy Volunteers

Healthy Adult Subjects

United States
GlycoMimetics Incorporated

Completed

A Study to Determine the Efficacy, Safety and Pharmacokinetics of GMI-1271 as Adjunct to Standard of Care for the Treatment of Multiple Myeloma

Multiple Myeloma

Ireland, Denmark, United Kingdom, Germany
Apollomics Inc.
Zhejiang CrownMab Biotech Co. Ltd

Recruiting

Study to Evaluate PK and Safety With Uproleselan Combined With Chemotherapy to Treat Chinese R/R AML Patients

Relapsed/Refractory AML

China
Apollomics Inc.
Zhejiang CrownMab Biotech Co. Ltd

Recruiting

Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML

Relapsed/Refractory AML

China
GlycoMimetics Incorporated
Celerion

Completed

A Study to Evaluate the PK, Safety and Tolerability of GMI-1271 With and Without Filgrastim in Healthy Adult Subjects

Healthy Volunteers

United States
GlycoMimetics Incorporated
University of Michigan

Completed

Phase I Study to Assess Safety and Pharmacokinetics of GMI-1271 in Healthy Adult Subjects

Healthy Volunteers

United States
GlycoMimetics Incorporated
Quotient Sciences

Completed

A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)

Healthy Subjects

United Kingdom
Lena Napolitano, MD
GlycoMimetics Incorporated

Terminated

Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia

COVID-19 Pneumonia

United States
GlycoMimetics Incorporated
University of Michigan

Terminated

Study to Assess Safety, Tolerability, and Efficacy of GMI-1271 in Patients With Calf-level Deep Venous Thrombosis (DVT)

Deep Venous Thrombosis

United States
GlycoMimetics Incorporated

Completed

Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy in AML

Leukemia, Myeloid, Acute

United States, Ireland, Australia
GlycoMimetics Incorporated

Active, not recruiting

Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Canada, Spain, Australia, Netherlands, France, Ireland, Italy, United Kingdom
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; GlycoMimetics Incorporated

Completed

Uproleselan (GMI-1271) for GI Toxicity Prophylaxis During Melphalan-Conditioned Autologous Hematopoietic Cell Transplantation (Auto-HCT) for Multiple Myeloma (MM)

Multiple Myeloma

United States
Brian Jonas
National Cancer Institute (NCI); GlycoMimetics Incorporated

Recruiting

Uproleselan, Azacitidine, and Venetoclax for the Treatment of Treatment Naive Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of Age on the Pharmacokinetics, Safety and Tolerability of IV Rivipansel.

Healthy

United States
GlycoMimetics Incorporated
Celerion

Completed

Placebo-Controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1359 in Healthy Volunteers

Healthy

United States
National Cancer Institute (NCI)

Suspended

Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

Acute Myeloid Leukemia

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel on Subjects With Renal Impairment and in Healthy Subjects

Healthy | Renal Impairment

United States
Ergoterapia Manoegomito Sagl

Unknown

EFFECTIVENESS OF GRADED MOTOR IMAGERY TO PREVENT CRPS IN PATIENTS WITH DISTAL RADIUS FRACTURE AFTER SURGERY

Surgery | Distal Radius Fracture | CRPS (Complex Regional Pain Syndromes) | Wrist Fracture
National Cancer Institute (NCI)
Childrens Oncology Group (COG); LLS PedAL LLC

Recruiting

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory and That Expresses E-selectin Ligand on the Cell Membrane

Down Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Recurrent Mixed Phenotype Acute Leukemia | Refractory Mixed Phenotype Acute Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy | Myelodysplastic...

United States
M.D. Anderson Cancer Center

Active, not recruiting

Uproleselan, Cladribine, and Low Dose Cytarabine for the Treatment of Patients With Treated Secondary Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

United States
GlycoMimetics Incorporated

Completed

Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease

Sickle Cell Disease

United States
University of Pittsburgh
National Institute of Mental Health (NIMH); Kaiser Foundation Research Institute

Withdrawn

Bridging the Gap to Improve Mental Health Treatment Utilization

Depression | Anxiety | Suicidal Ideation | Adolescent Behavior

United States
GlycoMimetics Incorporated

Terminated

A Study to Determine Safety and Tolerability of GMI-1359 in Subjects With HR+ Metastatic Breast Cancer

Breast Cancer | Breast Cancer Metastatic | HR+ Metastatic Breast Cancer

United States
St. Ambrose University

Completed

Graded Motor Imagery and Fall Risk in Older Adults (GMI)

Balance | Fall Risk

United States
GlycoMimetics Incorporated

Terminated

Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Vaso-occlusive Crisis | Pain Crisis | Sickle Cell Disorders

United States, Canada
University of Tromso
University Hospital of North Norway

Recruiting

A Comparison of Two Treatments for CRPS and Changes in Resting-State Connectivity of Cerebral Networks.

Complex Regional Pain Syndrome

Norway
Artvin Coruh University
Marmara University

Active, not recruiting

The Effect of Graded Motor Imagery on Pain and Function in Individuals With Knee Osteoarthritis

Knee Osteoarthritis | Limitation, Mobility

Turkey
GlycoMimetics Incorporated

Completed

Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis

Sickle Cell Disease | Vaso-occlusive Crisis | Pain Crisis

United States, Canada
IRCCS San Camillo, Venezia, Italy

Unknown

Graded Motor Imagery for Patients Within a Year After Stroke. (GMI)

Stroke

Italy
GlycoMimetics Incorporated

Completed

Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease

Anemia, Sickle Cell

United States, Canada
Marmara University

Recruiting

Graded Motor Imagery Training in Shoulder Impingement Syndrome

Pain | Shoulder Impingement Syndrome

Turkey
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of GMI-1070 on Qtc Intervals in Healthy African-American Adult Subjects

Healthy

United States
VA Office of Research and Development

Completed

Group Motivational Interviewing (GMI) For Homeless Veterans In VA Services

Alcoholism | Dual Diagnosis | Substance-related Disorders

United States
VA Office of Research and Development

Completed

Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed Veterans (GMI-IHMDs)

Alcohol Dependence | Dual Diagnosis | Drug Dependence

United States
Thomas Jefferson University

Completed

Linguistically-Tailored Mobile Intervention for the Improvement of Follow Up for Abnormal Pap Test Results

Cervical Carcinoma

United States
Norwegian University of Science and Technology

Completed

Effects of Systematic Patient Feedback on Therapy Outcome

Mental Disorders

Norway
Hacettepe University

Completed

The Effects of "Workplace Health Promotion Program" on Pain, Fatigue, Stress in Nurses

Pain | Fatigue | Work-Related Stress Disorder | Nurses
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Phase 2 Trial of Donafenib in 131I-Refractory Differentiated Thyroid Cancer

Differentiated Thyroid Cancer

China
Hopital du Sacre-Coeur de Montreal

Completed

How Much Opioids Do You Need After Your Emergency Department Visit

Acute Pain

Canada
The Cleveland Clinic

Completed

Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action (CIC)

Interstitial Cystitis

United States
Catharina Ziekenhuis Eindhoven
Erasmus Medical Center

Completed

Mean Systemic Filling Pressure and Heart Performance Predicting Fluid Responsiveness

Cardiac Output, High

Netherlands
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Epidemiology of Breast Arterial Calcification

Heart Diseases | Cardiovascular Diseases | Coronary Disease
Université de Sherbrooke

Completed

Investigation of the Efficacy of tDCS in the Treatment of Complex Regional Pain Syndrome (CRPS) Type 1

Reflex Sympathetic Dystrophy

Canada
Sanofi Pasteur, a Sanofi Company

Recruiting

Study of a Respiratory Syncytial Virus Candidate Formulation in Adults Aged 60 Years and Older

Healthy Volunteers | Respiratory Syncytial Virus Infection

Australia
Sanofi Pasteur, a Sanofi Company

Completed

Safety Surveillance of VaxigripTetra® and Efluelda® Influenza Vaccines in Europe During the Influenza Season 2022/23

Influenza (Healthy Volunteers)

Germany, Finland
McGill University

Completed

Personalized Upper Extremity Rehabilitation for Persons With Stroke (SUPER)

Stroke

Canada
Finnish Institute for Health and Welfare
University of Helsinki; Tampere University; University of Eastern Finland; Strategic...

Recruiting

Adolescent Interpersonal Counseling in Primary Care

Major Depressive Disorder | Depressive Symptoms Mild to Moderate in Severity

Finland
Shionogi

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants

Gram-Negative Bacterial Infections

United States, South Africa, Taiwan
Novo Nordisk A/S

Completed

A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation II

Healthy Volunteers; High Cholesterol

United States

Search clinical trials for: healthy volunteers, GMI-1271

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