Search clinical trials for: high cardiovascular risk

Total 84986 results

The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Obeservational Cohort for Evaluating Future Cardiovascular Disease With High Metabolic Risks (Charm)

Metabolic Disease
Eli Lilly and Company

Not yet recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Canada, Australia, Germany, Mexico, Argentina, Brazil, Hungary, Austria, India, Poland, Slovakia, Spain, Netherlands, Turkey, Czechia, United Kingdom, Denmark, Puerto Rico, France, Israel
West Michigan Cancer Center
Veta Health

Recruiting

Expanding Access to Care Through Telemedical Support for Vital Sign Monitoring in High-risk Patients With Cancer

Hypertension

United States
Supergene, LLC

Not yet recruiting

Non-immunogenic Recombinant Staphylokinase vs Placebo in Patients With Intermediate High-risk Pulmonary Embolism

Pulmonary Embolism

Russian Federation
Tufts University
National Institute on Minority Health and Health Disparities (NIMHD); Tougaloo... and other collaborators

Not yet recruiting

Delta GREENS Food is Medicine Intervention

Obesity | Diabetes | High Blood Pressure | Cardiometabolic Risk Factors | Nutrition Security

United States
Medical College of Wisconsin
Advancing a Healthier Wisconsin Endowment; Food for Health, Inc.

Not yet recruiting

Preventing Obstetric Complications With Dietary Intervention (PLATE)

Preeclampsia | Gestational Diabetes | High Risk Pregnancy | Gestational Hypertension
Beijing Tiantan Hospital

Not yet recruiting

Tirofiban for Patients With intraCranial Artery Stenosis and High-risk Acute Non-disabling Cerebrovascular Events(CHANCE-4）

TIA | Ischemic Stroke, Acute | Symptomatic Intracranial Artery Stenosis

China
Fundación EPIC

Recruiting

PREVAIL Paclitaxel-coated Balloon in Small Coronary Disease and High-bleeding Risk Patients (PARIS)

Coronary Artery Disease

Spain
AOP Orphan Pharmaceuticals AG
GCP-Service International Ltd. & Co. KG; ANOVA CRO s.r.o.; PharmaLex Belgium; Aixial...

Recruiting

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

Pulmonary Arterial Hypertension

Austria, Spain, France, Germany, Italy, Czechia, Hungary, Poland, Portugal, Romania
Federal State Budgetary Institution National Medical...
Kemerovo Cardiology Center, Tarasov Roman Sergeevich; Tomsk National Research...

Recruiting

Management Tactics for Patients High Risk With Acute Coronary Syndrome Without ST Segment Elevation and Multivessel Coronary Artery Disease (NSTE-ACSMT)

Coronary Syndrome, Acute, Non-ST Elevation, High Risk Patients

Russian Federation
Woo-Keun Seo

Not yet recruiting

Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk Patients

Carotid Artery Diseases
Alnylam Pharmaceuticals

Recruiting

Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3) (KARDIA-3)

Hypertension | High Cardiovascular Risk

United States
University of Bonn
Federal Ministry of Food and Agriculture (BMEL); Federal Office for Agriculture...

Recruiting

Acute Effects of Legume-enriched Meals Compared to Western Diet Meals on Postprandial Metabolism in Participants With Increased Cardiometabolic Risk (LeguPlan_1)

Cardiovascular Diseases | Metabolic Syndrome

Germany
Universitat de Lleida
Pharmactive Biotech Products S.L.U

Recruiting

ABG+/GarlACE Effects on Cardiovascular Risk Factors in Subjects With Grade I Hypertension (GARDOSE)

Hypertension

Spain
National Taiwan University Hospital

Not yet recruiting

Remimazolam in High Risk ERCP Patients

the Severity and Duration of Intraoperative Hypotension
Federal University of Paraíba
City University of New York

Recruiting

High-definition Transcranial Direct Current Stimulation and Chlorella Pyrenoidosa to Reduce Cardiovascular Risk (HD-TDCS)

Cardiovascular Diseases | Long Covid19

Brazil
Novartis Pharmaceuticals

Not yet recruiting

VictORION-INCLUSION is a Multicenter, Randomized, Open Label, Study of Inclisiran + Usual Care vs Usual Care Alone in an Inclusive and Underrepresented Population at High Risk for or Diagnosed With ASCVD Within a Pragmatic EHR Framework. (V-INCLUSION)

Atherosclerotic Cardiovascular Disease
Affiliated Hospital of Nantong University

Recruiting

Mitoxantrone Hydrochloride Liposome Combination Regimen in the Treatment of High-risk/Extramedullary Multiple Myeloma

Multiple Myeloma

China
Beijing Tiantan Hospital

Not yet recruiting

Early Intensive Antihypertensive Treatment in High-Risk Population of intraCerebral Hemorrhage ExpanSion Predicted by Artificial Intelligence (ARCHES)

Cerebral Hemorrhage
Qilu Hospital of Shandong University
Chinese PLA General Hospital; Xuanwu Hospital, Beijing; Shenzhen People's Hospital and other collaborators

Not yet recruiting

Evaluation of Vascular Structure in Elderly Using High-frequency Ultrasound and Construction of a Multimodal Risk Assessment System for Cardiovascular Diseases: a Multicenter Study

Stroke | Coronary Disease | Atherosclerosis

China
Assistance Publique - Hôpitaux de Paris
Action Research Group

Not yet recruiting

Antagonization of Heparin With Protamine Sulfate After TAVI (ATLANTIS-Prota)

Aortic Valve Stenosis | Heart Valve Diseases
University of Utah

Recruiting

Smoldering Myeloma High-Risk Patient Observation and Longitudinal Insight Trial (SPOTLIGHT)

Smoldering Multiple Myeloma

United States
M.D. Anderson Cancer Center
Pfizer

Not yet recruiting

Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

Multiple Myeloma | Post-transplant MRD-guided Maintenance Therapy | Pre-transplant Purging

United States
University Hospital, Montpellier

Not yet recruiting

Impact of Assessment and Management of Comorbidities in Internal Medicine on Cardiovascular Risk (COMMEDCARDIO)

Patients at High-Risk of a Cardiovascular Event
Midwest Heart & Vascular Specialists

Recruiting

Amyloidosis Incidence in High-Risk Cardiac Device Patients

AL Amyloidosis | Amyloid | Cardiac Amyloidosis | Amyloidosis Cardiac | Systemic Amyloidosis | ATTR Amyloidosis Wild Type | Infiltrative Cardiomyopathy, Amyloid

United States
European Myeloma Network
Pfizer

Not yet recruiting

Use of Elranatamab in Patients With High-risk Smoldering Multiple Myeloma (ERASMM)

Smoldering Multiple Myeloma

Netherlands, Finland, Norway, France, Italy, Greece
University of California, San Francisco
Jazz Pharmaceuticals

Not yet recruiting

Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma

Thrombotic Microangiopathies | Neuroblastoma | High-risk Neuroblastoma | Transplant-Associated Thrombotic Microangiopathy

United States
National Cancer Institute (NCI)

Recruiting

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United States
CHX Technologies Inc.
The Research Institute of St Joe's Hamilton; St. Joseph's Health System - Centre...

Not yet recruiting

A Pilot Observation and Feasibility Study of Prevora, Integrated Into Homecare Visits of High-risk Adults

Dialysis | COPD (Chronic Obstructive Pulmonary Disease) | Chronic Metabolic Disorder | CHF (Congestive Heart Failure)
Niguarda Hospital

Recruiting

Ultrasound-assisted, Catheter-directed Thrombolysis for Acute Intermediate-high-risk Pulmonary Embolism (USAT IH-PE)

Pulmonary Embolism

Italy
Wuhan Union Hospital, China

Recruiting

Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma

Multiple Myeloma | Extramedullary Multiple Myeloma | Primary Plasma Cell Leukemia

China
Regeneron Pharmaceuticals

Not yet recruiting

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma (LINKER-MGUS1)

Monoclonal Gammopathy of Undetermined Significance (MGUS) | Smoldering Multiple Myeloma (SMM)
Boston Scientific Corporation

Not yet recruiting

VITALYST Early Feasibility Study in High-Risk PCI Patients (VITALYST EFS) (VITALYST EFS)

Heart Disease, Coronary | High-risk Percutaneous Coronary Intervention

United States, Sweden
Novo Nordisk A/S
Duke Clinical Research Institute

Not yet recruiting

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack (ARTEMIS)

Cardiovascular Risk | Acute Myocardial Infarction (AMI)

Canada, China, United States, Germany, Spain, Korea, Republic of, Netherlands, Australia, Italy, Denmark, India, United Kingdom, Argentina, Turkey, Mexico, Malaysia, Czechia, Poland, Brazil, France, Japan, Bulgaria, Greece, Israel
Carl Ola Landgren, MD, PhD
Janssen Scientific Affairs, LLC

Recruiting

Teclistamab or Talquetamab in Combination With Daratumumab for High-Risk Smoldering Myeloma (REVIVE Study) (REVIVE)

Multiple Myeloma

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Oriental Intervention for Enhanced Neurocognitive Health (Orient) Diet in Populations With High Risk of Stroke (ENDS)

High Risk of Stroke

China
Fu Wai Hospital, Beijing, China

Not yet recruiting

Ticagrelor Single Antiplatelet Therapy in Patients With High Risk of Bleeding After DCB for Coronary Small Vessel Disease

Coronary Heart Disease

China
Institut National de la Santé Et de la Recherche...

Not yet recruiting

Risk Markers of Arterial Aging. The Paris Prospective Study III-2 (PPS3-2)

Arterial Stiffness
Henrik Wiggers

Recruiting

Hyperpolarized MRSI in Ischemic Heart Disease: A Metabolic Investigation of the Heart Muscle

Ischemic Heart Disease

Denmark
Washington University School of Medicine
Aminu Kano Teaching Hospital; University of Abuja Teaching Hospital; National... and other collaborators

Not yet recruiting

Utilization of Aspirin for Prevention of Pre-Eclampsia in Nigeria: A Explanatory Sequential Mixed Methods Study

Hypertensive Disorders of Pregnancy

Nigeria
First Affiliated Hospital of Kunming Medical University

Not yet recruiting

Norepinephrine Prevent Post-induction Hypotension in High-risk Patients

Blood Pressure | Anesthesia | Norepinephrine
Chinese Academy of Medical Sciences, Fuwai Hospital

Not yet recruiting

Residual Inflammatory Risk-Guided colcHicine in Elderly Trial (RIGHT)

Percutaneous Coronary Intervention | Elderly Patients | Multivessel Coronary Artery Disease | C-Reactive Protein

China
Niguarda Hospital

Recruiting

Ischemic And Bleeding Risk Assessment After TAVR (FOCUS ONE)

Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement

Italy, Belgium, Czechia, Chile, Spain
Stadtspital Zürich
Ospedale Regionale di Lugano

Recruiting

Diuretic Strategies in Acute Heart Failure Patients at High Risk for Diuretic Resistance (P-Value-AHF)

Acute Heart Failure | Diuretic Resistance

Switzerland
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Changhai Hospital

Recruiting

Comprehensive Management of High-risk PopuLatIon of Stroke Based on Social Network (COMPLIANCE-MT)

Cardiovascular Diseases | Vascular Diseases | Stroke | Cerebrovascular Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases

China
Regeneron Pharmaceuticals

Recruiting

A Proof-of-Concept Trial to Study the Safety and Activity of Linvoseltamab in Participants With Smoldering Multiple Myeloma at High Risk of Developing Multiple Myeloma

Smoldering Multiple Myeloma (SMM)

Spain
University of Michigan Rogel Cancer Center
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplant

United States
Yonsei University

Recruiting

Tailored Anti-platelet Therapy After DES Implantation in High-risk Patients

Coronary Artery Disease

Korea, Republic of
University of Southern California
University of California, Los Angeles; University of California, Irvine

Recruiting

Reducing Blood Pressure in Patients With High Cardiovascular Risk in the Safety-Net (BP-REACH)

Myocardial Infarction | Stroke | Hypertension

United States

Search clinical trials for: high cardiovascular risk

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