Search clinical trials for: high surgical risks

Total 30045 results

Nantes University Hospital
Abbott; Ministère de la Santé

Recruiting

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (MITRA-HR)

Mitral Regurgitation

France, Monaco
University of Cape Town

Completed

BNP Evaluation Before Surgery Study: an Observational Study of Natriuretic Peptide Levels Prior to Surgery. (EPIC-2)

Surgery, Cardiovascular

South Africa
W.L.Gore & Associates

Completed

GORE® Embolic Filter in Carotid Stenting for High Risk Surgical Subjects (EMBOLDEN) (EMBOLDEN)

Carotid Artery Stenosis
National Cancer Center, Korea

Recruiting

The Clinical Effectiveness and Safety of Intravesical Mitomycin-C and Gemcitabine Sequential Therapy (IMGeS)

Bladder Cancer

Korea, Republic of
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Obeservational Cohort for Evaluating Future Cardiovascular Disease With High Metabolic Risks (Charm)

Metabolic Disease
Aswan University

Recruiting

Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients

Critical Illness | Acute Kidney Injury

Egypt
Biocad

Recruiting

Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (LEVENTA)

Axial Spondyloarthritis

Russian Federation, Belarus
University of Calgary

Not yet recruiting

Post-surgical Outcomes With Anabolic Agent Use in High-risk Ankle Fractures: A Pilot RCT

Ankle Fractures
Odense University Hospital
Karolinska University Hospital

Not yet recruiting

The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients. (EPICURE)

Gastric Cancer | Peritoneal Metastases | Chemotherapy, Adjuvant | Minimally Invasive Surgical Procedures

United States, Sweden, Denmark, France, Germany
Hospital del Mar

Not yet recruiting

Complications of Cholecystostomy in ACC (Chole_ACC)

Cholecystitis
Institut d'Investigació Biomèdica de Girona Dr....

Recruiting

Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection. (PROFIMESH)

Colorectal Cancer | Wound Infection | Hernia Incisional

Spain
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Korea, Republic of, United Kingdom, United States, Poland, Germany, Brazil, Spain, Taiwan, Hungary, Japan, Canada, Argentina, Australia
Takeda

Recruiting

A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment

Plaque Psoriasis

United States, Canada, Poland, Italy, Japan
M.D. Anderson Cancer Center

Recruiting

Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy

Ovarian Cancer

United States
Ruijin Hospital

Recruiting

A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries(SPiM-RWS-GYN)

Gynecological Surgeries

China
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
National Cancer Institute (NCI)

Recruiting

Durvalumab With Gemcitabine and Cisplatin for the Treatment of High Risk Resectable Liver Cancer Before Surgery

Intrahepatic Cholangiocarcinoma

United States
University Hospital, Antwerp

Recruiting

Airway Interventions During Intravenous Anesthesia in Children Undergoing Direct Laryngoscopy for Surgical Procedures Using High Flow Nasal Versus Low Flow Oxygen. A Pilot Study.(Flowkid)

Child | Laryngoscopy | Oxygen Therapy

Belgium
Fred Hutchinson Cancer Center
ImmunoGen, Inc.

Recruiting

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm | Mixed Phenotype Acute Leukemia

United States
University of Washington
Eli Lilly and Company

Not yet recruiting

Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma

Retroperitoneal Sarcoma

United States
St. Jude Children's Research Hospital

Recruiting

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

Rhabdomyosarcoma

United States
AbbVie

Recruiting

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata (Up-AA)

Alopecia Areata

United States, Australia, Japan, Puerto Rico, New Zealand, China, Canada, Brazil, United Kingdom, Korea, Republic of
Radboud University Medical Center
ETH Zurich; VU University of Amsterdam; Flash Pathology BV

Recruiting

Validation of Rapid On-site Diagnostics in Early Stage Lung Cancer Sampling With a Higher Harmonic Generation Microscope (VALIDIAG)

Lung Cancer

Netherlands
Niguarda Hospital

Recruiting

Ischemic And Bleeding Risk Assessment After TAVR (FOCUS ONE)

Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement

Italy, Belgium, Czechia, Chile, Spain
Dow University of Health Sciences

Recruiting

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

Surgical Wound | Surgical Site Infection | Wound Infection | Surgical Incision | Seroma | Post Operative Wound Infection | Emergency Laparotomies | Laparotomies

Pakistan
Kasr El Aini Hospital

Recruiting

Gastric Insufflation During Facemask Ventilation at Different Levels of End-expiratory Pressure in Obese Patients

Obese | Gastric Insufflation | Positive End Expiratory Pressure | Face-mask Ventilation

Egypt
Northwell Health

Recruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme, Adult

United States
Elsan

Recruiting

Rotator Cuff Repair Under Isolated Loco-regional Anesthesia (AGORA)

Shoulder Cuff Surgical Repair

France
Boehringer Ingelheim

Recruiting

Lunsayil 1: A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States, Korea, Republic of, Israel, Spain, Australia, Japan, Italy, Germany, Denmark, Belgium, Lithuania, China, Canada, Malaysia, Singapore, New Zealand, France, Mexico, Netherlands, Greece, United Kingdom, Bulgaria, Philipp... and more
Heinrich-Heine University, Duesseldorf

Recruiting

Computer-assisted Risk Evaluation in the Early Detection of Psychotic Disorders (CARE)

Psychotic Disorders | Prevention

Germany
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

Prostate Adenocarcinoma | Stage IIIB Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8

United States
Hangzhou Highlightll Pharmaceutical Co., Ltd

Recruiting

The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis

Plaque Psoriasis

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

Malignant Glioma | Diffuse Glioma

United States
Rijnstate Hospital
University Medical Center Groningen; Maastricht University Medical Center; Leiden... and other collaborators

Recruiting

Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients (PREPARATION)

Postoperative Complications | Interdisciplinary Communication | Surgical Procedures, Operative | Preoperative Care | Cost-Benefit Analysis | Noncardiac Surgery | Comorbidities and Coexisting Conditions | Patient Care Team

Netherlands
Balgrist University Hospital
Industry (Schülke & Mayr AG, Switzerland and Germany)

Recruiting

General Decolonization With Octenisan® Set Before Elective Orthopedic Surgery (BALGDEC)

Elective Surgery | High Risk | Prevention of Surgical Site Infections | Randomized-controlled Trial

Switzerland
Erasmus Medical Center

Not yet recruiting

Biopsy Versus Resection in Elderly Glioblastoma Patients. A Prospective Cohort Study. (BIOPSY)

Glioblastoma

Netherlands
Humanitas Clinical and Research Center
Società Italiana Anestesia, Analgesia, Rianimazione e Terapia Intensiva -...

Recruiting

HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery (HISTAP)

Blood Pressure | Complication,Postoperative | Intraoperative Hypotension

Italy
Rigshospitalet, Denmark
Hvidovre University Hospital; Bispebjerg Hospital; The Novo Nordic Foundation; Aalborg... and other collaborators

Recruiting

The Fast-track Centre for Hip and Knee Replacement Database (FCD)

Patient Satisfaction | Hip | Knee | Fast-track Surgery | Enhanced Recovery After Surgery | Perioperative Medicine | Ambulatory Surgical Procedures | Perioperative/Postoperative Complications

Denmark
Peking University Cancer Hospital & Institute
Shanghai Ming Ju Biotechnology Co., Ltd.

Recruiting

Relmacabtagene Autoleucel as First-Line Therapy for High-Risk Large B-Cell Lymphoma

B-cell Lymphoma

China
Biomendex Oy

Recruiting

Clinical Study to Evaluate Adaptos®Ortho Wedge Bone Graft Substitute in High Tibial Osteotomy

Knee Deformity

Finland
Case Comprehensive Cancer Center

Recruiting

Surgical Study on Upfront or Recurrent High-Grade Glioma (WHO Grade III and IV) Electrical Activity

Glioblastoma | High Grade Glioma

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas

Soft Tissue Sarcoma | Recurrent Soft Tissue Sarcoma | Resectable Soft Tissue Sarcoma

United States
Eli Lilly and Company

Recruiting

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer (EMBER-4)

Breast Neoplasms

China, Japan, United States, Australia, Taiwan, Belgium, Canada, United Kingdom, Spain, France, Argentina, Ireland, Netherlands, Turkey, Czechia, Korea, Republic of, Finland, Hungary, Italy, Mexico, Brazil, Germany, India, Austria, Greece, Roman... and more
Balgrist University Hospital

Recruiting

Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery (BAPTIST)

Microbial Colonization | Surgical Site Infection | Antibiotic Resistant Infection

Switzerland
Pacira Pharmaceuticals, Inc

Recruiting

Innovations in Genicular Outcomes Registry (iGOR)

Knee Osteoarthritis

United States
Monash University
The Alfred

Recruiting

Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study (CALIPSO)

Surgical Site Infection

Australia, New Zealand
Boston Children's Hospital

Not yet recruiting

TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss

Surgical Blood Loss | Post Operative Hemorrhage | Surgical Hemorrhage
Bayer

Recruiting

A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real World Conditions When Taken in Addition to Standard Androgen Deprivation Therapy (ADT) in Indian Participants With High-risk Non-metastatic Castration-resistant Prostate Cancer (nmCRPC)

Non-metastatic Castration-resistant Prostate Cancer

India
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Melanoma | Sarcoma | Acute Myeloid Leukemia | Stage I Uterine Corpus Cancer AJCC v7 | Stage II Uterine Corpus Cancer AJCC v7 | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Stage III Pancreatic... and other conditions

United States
Second Affiliated Hospital, School of Medicine,...
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection

Resectable Esophageal Cancer

China

Search clinical trials for: high surgical risks

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