Search clinical trials for: intrathecal opioids

Total 1241 results

Mayo Clinic

Completed

Intrathecal Opioids for Colorectal Resection

Pain, Postoperative | Colorectal Surgery | Analgesic, Opioid

United States
University of Utah

Completed

Pilot Study on the Effect of Intrathecal Opioids on Immune Function in Humans With Cancer Pain

Cancer-associated Pain

United States
MedtronicNeuro

Completed

Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain

Chronic Pain | Pain, Back | Chronic Non-malignant Pain | Pain, Leg

United States
Mansoura University

Unknown

Effect of Intravenous Magnesium on Post-spinal Fentanyl Induced Pruritus Incidence

Magnesium Infusion in Post-spinal Opioid Pruritis

Egypt
Wahba bakhet
elite medical hospital

Completed

Neuroaxial Labour Analgesia

Labor Analgesia

Egypt, Kuwait
Mayo Clinic

Completed

Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery

Analgesia, Obstetrical | Obstetric Surgical Procedures

United States
Brigham and Women's Hospital

Terminated

Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study

Pain | Healthy | Pregnancy

United States
Šarić, Jadranka Pavičić, M.D.

Completed

Intrathecal Administration of Levobupivacaine and Opioids in Elderly

Adverse Reaction to Spinal Anesthetic

Croatia
Mayo Clinic

Completed

Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal Dose

Cesarean Section | Analgesia, Obstetrical

United States
Assiut University

Completed

Combined Intrathecal Morphine and Dexmedetomidine Analgesia (ITMandDEX)

Postoperative Pain
Baskent University

Completed

Intrathecal Levobupivacaine With Opioids for Caesarean Section

Elective Caesarean Section Surgeries

Turkey
University Hospital Freiburg

Completed

Prospective, Randomised, Single-Blinded, Monocentric Clinical Study to Compare Postoperative Analgesia and Outcome After Combined Paravertebral and Intrathecal Versus Thoracic Epidural Analgesia for Thoracotomy

Pain, Postoperative

Germany
NHS Greater Clyde and Glasgow

Completed

Observation of Respiration Following Regional Anaesthesia With Intrathecal Opioids for Caesarean Section

Respiratory Depression

United Kingdom
Columbia University
University of Southern California; Abdul Latif Jameel Poverty Action Lab; Bowdoin... and other collaborators

Not yet recruiting

E-mail Nudges for Prescribing Risky Drugs

Opioid Prescribing | Prescription Drug Misuse

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Not yet recruiting

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)

Chronic Pain | Opioid Withdrawal

United States
Fujian Cancer Hospital

Not yet recruiting

Double Dose of Third-generation EGFR-TKI Plus Intrathecal Pemetrexed Versus Double Dose of Third-generation EGFR-TKI in Patients With LM Progression Following the Treatment of Routine Dose of Third-generation EGFR-TKI

Leptomeningeal Metastasis

China
Hunan Province Tumor Hospital
Hunan Cancer Hospital

Recruiting

Efficacy and Resistance Mechanisms of IP in NSCLC With Leptomeningeal Metastases (EPIC)

Non-Small Cell Lung Cancer

China
Investigation Group Anesthesia, Resuscitation,...

Not yet recruiting

Monitoring Nociception Using NoL Index to Reduce Opioid-Related Complications in Laparoscopic Abdominal Surgery (SIMONE)

Postoperative Opioid-related Complications
Inova Fairfax Hospital

Not yet recruiting

Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator

Cesarean Section | Opioid Use Disorder | Post-operative Pain, Acute | Opioids; Harmful Use

United States
Ionis Pharmaceuticals, Inc.

Not yet recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Sichuan University

Recruiting

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

NSCLC | PD-1 Inhibitor | Leptomeningeal Metastasis | Low Dose Radiotherapy

China
Icahn School of Medicine at Mount Sinai

Not yet recruiting

Intrathecal Dexmedetomidine vs Epinephrine

Cesarean Section | Anesthesia, Spinal

United States
Muhammad Ilyas

Not yet recruiting

Impact of Intrathecal vs Intravenous Dexmedetomidine

Nausea and Vomiting, Postoperative
Assiut University

Not yet recruiting

Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia

Post Cesarean Analgesia
University of Kent
Kent Community Health NHS Foundation Trust; NHS Kent and Medway

Recruiting

DE-eSCALation of Opioids Post-surgical dischargE (DESCALE)

Opioid Dependence

United Kingdom
St. Jude Children's Research Hospital
AbbVie

Not yet recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

T-cell Lymphoma | T-cell Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States
University of Virginia

Not yet recruiting

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery

Pain, Postoperative

United States
Jagiellonian University

Recruiting

Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery

Anesthesia, General | Analgesics, Opioid | Anesthesia, Endotracheal

Poland
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Prospective Study of Whole-Brain RT Combined With Thiotepa Sheath Injection Combined With Systemic Therapy for the Primary Disease in the Treatment of Meningeal Metastases in Solid Tumors

Solid Tumor Leptomeningeal Metastasis

China
Assiut University

Not yet recruiting

Effect of Intrathecal Magnesium Sulfate Versus Intravenous Magnesium Sulfate on Postoperative Pain After Abdominal Hysterectomy

Abdominal Hysterectomy
Tribhuvan University Teaching Hospital, Institute...

Not yet recruiting

Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia

Visceral Pain
Schulthess Klinik

Not yet recruiting

Postoperative Pain After Implementation of Standardized Pain Therapy Management in Orthopaedic Patients (PAIN)

Postoperative Pain, Acute
Marmara University

Recruiting

Comparing Intrathecal Morphine With Modified Thoracoabdominal Nerve Block Through Perichondral Approach in Major Abdominal Surgery

Postoperative Pain | Opioid Use

Turkey
Wuhan Union Hospital, China

Not yet recruiting

Diagnosis of Leptomeningeal Metastasis and the Monitoring of Intrathecal Chemotherapy Efficacy in NSCLC

Diagnosis

China
Dalin Tzu Chi General Hospital

Not yet recruiting

Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section

Cesarean Section | Postsurgical Pain | Chronic Post-surgical Pain
Ataturk University

Recruiting

Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score: Prospective, Randomized Trial

Postoperative Recovery

Turkey
Ziauddin University

Not yet recruiting

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial (MROSF)

Oral Submucous Fibrosis

Pakistan
Tanta University

Recruiting

Analgesic Efficacy of Mid-Transverse Process to Pleura (MTP) Block and Intrathecal Morphine in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion

Idiopathic Scoliosis | Posterior Spinal Fusion | Intrathecal Morphine | Mid-Transverse Process Block

Egypt
The Affiliated Hospital Of Guizhou Medical University

Recruiting

Treatment of Vasospasm of Aneurysmal Subarachnoid Hemorrhage With Intrathecal Nicardipine - FAST-IT Trial

Aneurysmal Subarachnoid Hemorrhage | Vasospasm

China
Cairo University

Not yet recruiting

Intrathecal Non-preservative-free Morphine With Bupivacaine Versus Intrathecal Bupivacaine Alone for Analgesia in Unilateral Inguinal Hernia Repair Surgeries

Pain, Postoperative

Egypt
Centre Hospitalier Universitaire Vaudois

Not yet recruiting

Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty (PENGIT)

Analgesia | Post Operative Pain | Hip Arthropathy

Switzerland
Oman Medical Speciality Board
Armed Forces Hospital, Oman

Not yet recruiting

Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department (PASC)

Sickle-Cell Disease With Crisis
Guangzhou Medical University

Recruiting

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Leptomeningeal Metastasis

China
Bezmialem Vakif University

Recruiting

The Efficacy of Combined Intrathecal Morphine and PENG Block on Postoperative Pain in Hip Arthroplasty (PENG)

Postoperative Pain Management

Turkey
Wayne State University

Not yet recruiting

Ondansetron Use for Preventing Pruritus In Patients Undergoing Cesarean Section

Pruritus Caused by Drug

United States
Guangzhou Medical University

Not yet recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.

Leptomeningeal Metastasis
St. Jude Children's Research Hospital

Not yet recruiting

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mixed Phenotype Acute Leukemia

United States
South Valley University

Not yet recruiting

Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean Section

Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Ciusss de L'Est de l'Île de Montréal

Not yet recruiting

Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception. (ESMONOL)

Anesthesia | Opioid Use, Unspecified | Nociceptive Pain

Canada
Second Affiliated Hospital of Nanchang University
Changhai Hospital

Recruiting

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage

China

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