Search clinical trials for: intravascular hemolysis

Total 657 results

Cedars-Sinai Medical Center

Not yet recruiting

HEMolysis in a Percutaneous Axial Flow LVAD, Effects of Pentoxifylline in a Randomized Controlled Trial

Acute Decompensated Heart Failure | Hemolysis Intravascular

United States
Massachusetts General Hospital
Spina, Stefano, M.D., Massachusetts General Hospital; Marrazzo, Francesco,... and other collaborators

Recruiting

Effects of Nitric Oxide on the Endothelium During Hemolysis.

Cardiovascular Diseases | Endothelial Dysfunction | Cardiovascular Risk Factor | Hemolysis Intravascular

United States
Alexion Pharmaceuticals, Inc.

Available

Danicopan Early Access Program

Paroxysmal Nocturnal Hemoglobinuria | PNH | Extravascular Hemolysis
Apellis Pharmaceuticals, Inc.

Completed

Pilot Study to Assess Safety, Preliminary Efficacy and Pharmacokinetics of S.C. Pegcetacoplan (APL-2) in PNH Subjects. (PADDOCK)

Paroxysmal Nocturnal Hemoglobinuria

Hong Kong, Thailand, New Zealand, Malaysia
Apellis Pharmaceuticals, Inc.

Completed

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States
Apellis Pharmaceuticals, Inc.

Completed

A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered Pegcetacoplan (APL-2) in Subjects With PNH

PNH

Serbia, Bulgaria
Rabin Medical Center

Unknown

Is There Intravascular Hemolysis in Patients With Pulmonary Hypertension?

Pulmonary Artery Hypertension

Israel
Medical University of Gdansk

Recruiting

Intravascular Clotting (POCUS) - Marker of the Timing and Severity of Cardiac Arrest; Indicator of Futile Resuscitation

Cardiac Arrest

Poland
Affiliated Hospital of Nantong University

Recruiting

Vivifrail Program on the Degree of Debilitation in Hospitalized Patients After Venous Hemolysis in Acute Ischemic Stroke

Ischemic Stroke | Frailty | Exercise Therapy

China
Inmunova S.A.
Chemo Research; KLIXAR; Linical; Crovelis

Not yet recruiting

Efficacy of INM004 in Children With STEC-HUS

Hemolytic-Uremic Syndrome

Argentina
Novartis Pharmaceuticals

Not yet recruiting

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction (V-ACCELERATE)

Plaque, Atherosclerotic
Massachusetts General Hospital

Not yet recruiting

Study to Determine the Clinical Significance of Intravascular OCT-NIRAF

Cardiovascular Diseases | Coronary Artery Disease

United States
Deutsches Herzzentrum Muenchen
EvidentIQ Germany GmbH; Institute of AI and Informatics in Medicine Technical... and other collaborators

Not yet recruiting

Intracoronary Stenting and Additional Results Achieved by ShockWAVE Coronary Lithotripsy (ISAR-WAVE)

Coronary Artery Disease

Germany
Sanjay Gandhi Postgraduate Institute of Medical...

Recruiting

Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients

Septic Shock | Disseminated Intravascular Coagulation

India
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

Thrombocytopenia | Surgery | Acute Kidney Injury | Hemolysis

United States
Guangzhou Women and Children's Medical Center

Recruiting

Prediction and Evaluation by ETCOc of Neonatal Hyperbilirubinemia Cohort (PREVENT)

Neonatal Hyperbilirubinemia | Neonatal Jaundice | Hemolysis Neonatal

China
Mayo Clinic

Recruiting

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Preeclampsia

United States
Rede Optimus Hospitalar SA
Shockwave Medical, Inc.

Not yet recruiting

Shockwave™Peripheral Intravascular Lithotripsy Balloon for Advanced Endovascular Aortic Repair (TEVAR)

Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture | Abdominal Aortic Aneurysm Without Rupture | Thoracic Aortic Aneurysm Without Rupture
Shanghai Zhongshan Hospital

Recruiting

IVUS CHIP China Registry

Complex Higher Risk Indicated Patients Undergoing PCI

China
Fundación EPIC

Recruiting

Comparison Between Optical Coherence Tomography and Intravascular Ultrasound for Intermediate Left Main Coronary Artery Lesions (EMPERATRIZ)

Coronary Disease

Spain
McMaster University
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Dial-Bicarb Trial: Effects of a Lower vs. Higher Concentration of Dialysate Bicarbonate

Renal Failure | Hemolysis
Atara Biotherapeutics

Recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

High-grade B-cell Lymphoma | MCL | Diffuse Large B-cell Lymphoma (DLBCL) | Relapsed/Refractory B-cell Non-Hodgkin Lymphoma | DLBCL/High-grade B-cell Lymphoma With MYC and BCL2 Rearrangements | Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma | LBCL With IRF4 Rearrangement | High-grade B-cell... and other conditions

United States
Xijing Hospital

Recruiting

Intravascular Lithotripsy Versus Conventional Therapy for Severely Calcified Coronary Artery Lesions (REC-CHIPCAC)

De Novo Stenosis | Severely Calcified Coronary Stenoses

China
Institute of Hematology & Blood Diseases Hospital...
Juventas Cell Therapy Ltd.

Recruiting

CNCT19 for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.

Autoimmune Hemolytic Anemia | Autologous CD19 CAR-T | Failure of Three or More Lines of Therapy

China
Chonnam National University Hospital
Samsung Medical Center

Recruiting

OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts (FRAME-AMI3)

Myocardial Infarction | ST Elevation Myocardial Infarction

Korea, Republic of
Ahram Canadian University

Recruiting

Biodex Training in Hemodialysis Females With Osteopenia

Hemolysis

Egypt
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Nanchang University; Seoul St. Mary's Hospital and other collaborators

Not yet recruiting

FFR Versus IVUS With Angiography-Derived FFR for Clinical Outcomes in Patients With Coronary Artery Disease (FLAVOUR III)

Coronary Artery Disease

Korea, Republic of, China
Institute of Hematology & Blood Diseases Hospital...
Suzhou Fundamenta Therapeutics

Recruiting

CAR-T for Autoimmune Hemolytic Anemia Patients Who Have Failed Three or More Lines of Therapy

Autoimmune Hemolytic Anemia | CD19 CAR-T Cell Infusion

China
Charles University, Czech Republic

Not yet recruiting

Renal Function and Hemolysis After Pulsed-field Ablation for Atrial Fibrillation

Atrial Fibrillation

Czechia
Bolt Medical

Recruiting

Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE) (FRACTURE)

Coronary Artery Disease | Coronary Artery Calcification

Netherlands, United Kingdom
Soonchunhyang University Hospital
Boston Scientific Corporation; The Catholic University of Korea; Eulji University and other collaborators

Recruiting

Assessment of Cutting-Balloon Angioplasty With Everolimus-Eluting Stent(EES) in the Treatment of Coronary Calcified Lesion(CCL) Guided by Intravascular Ultrasonography(IVUS)

Coronary Artery Disease

Korea, Republic of
Harbin Medical University

Not yet recruiting

Study on the Improvement of Myocardial Microcirculation After Acute Anterior Myocardial Infarction

Intravascular Imaging and Microvascular Obstruction
Cardiovascular and Interventional Radiological...
Shockwave Medical, Inc.

Not yet recruiting

Chronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study (CALCIO)

Chronic Limb-Threatening Ischemia
4th Military Clinical Hospital with Polyclinic,...
Medical Research Agency, Poland

Not yet recruiting

Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CAS (NOTICE-CAS)

Stroke | Carotid Artery Stenting | Carotid Artery Stenosis

Poland
University of Leipzig

Not yet recruiting

Comparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal Lesions (CRACK-IT)

Peripheral Arterial Disease

Germany
AstraZeneca

Recruiting

A Prospective, Non-interventional, Observational Study of Presentation, Treatment Patterns and Outcomes in Atypical Hemolytic Uremic Syndrome Patients

Atypical Hemolytic Uremic Syndrome(aHUS)

China
Charles University, Czech Republic

Not yet recruiting

Hemolysis During Pulsed-field and Radiofrequency Ablation

Atrial Fibrillation | Hemolysis | Pulsed-field Ablation

Czechia
Baim Institute for Clinical Research
C. Michael Gibson, MS, MD; Akiko Maehara, MD; Robert W. Yeh, MD; Ajay Kirtane, MD; Kathleen Kearney,... and other collaborators

Not yet recruiting

Shockwave Lithoplasty Compared to Cutting Balloon Treatment in Calcified Coronary Disease - A Randomized Controlled Trial (Short-Cut)

Treatment in Calcified Coronary Disease

United States
Hospital Universitario La Fe

Recruiting

Plaque Modification And Impact On Microcirculatory Territory After Drug-Coated Balloon Percutaneous Coronary Intervention (PLAMI). (PLAMI)

Coronary Artery Disease | Percutaneous Coronary Intervention | Microvascular Coronary Artery Disease | Intravascular Ultrasound | Drug Coated-balloon | Plaque Modification

Spain
China National Center for Cardiovascular Diseases

Recruiting

Functional Diagnostic Accuracy of Ultrasonic Flow Ratio in Assessment of Left Main Coronary Artery Stenosis (FUNCTION II)

Left Main Coronary Artery Disease

China
China National Center for Cardiovascular Diseases

Not yet recruiting

Functional Diagnostic Accuracy of Ultrasonic Flow Ratio in Assessment of Coronary Artery Lesions (FUNCTION)

Coronary Artery Stenosis
Institute of Hematology & Blood Diseases Hospital...

Recruiting

The Safety and Efficacy of Zanubrutinib in Refractory/Relapsed Autoimmune Hemolytic Anemia

Refractory/Relapsed Autoimmune Hemolytic Anemia

China
Closed Joint-Stock Company NeoCor
Research Institute for Complex Problems of Cardiovascular Diseases, Russia; CT Medical Limited Liability Company

Recruiting

Post-market Clinical Monitoring of the Safety and Efficacy of the Aortic Valve Bioprothesis (TiAra)

Aortic Valve Disease | Artificial Heart Valves

Russian Federation
Qilu Hospital of Shandong University

Recruiting

The Proactive Diagnostic Value of Hemostatic Biomarkers in Disseminated Intravascular Coagulation

Disseminated Intravascular Coagulation

China
University Hospital, Tours

Recruiting

French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy" (MATRIX)

Kidney Diseases | Hemolytic Uremic Syndrome | Acute Kidney Injury | Thrombotic Microangiopathy | Nephrology

France
Aristotle University Of Thessaloniki
University of Southampton; National and Kapodistrian University of Athens

Not yet recruiting

Deploying Novel Imaging Modalities Towards a Three-dimensional (3D) CARDIOvascular PATHology (3D-CARDIOPATH)

Coronary Artery Disease | Aortic Valve Disease | STEMI | Cardiovascular Pathology | Aortic Valve Calcification
University of Rome Tor Vergata

Recruiting

Shockwave Induced Attenuation of Calcified Plaques Quantified With OCT (SCALPO)

Coronary Artery Calcification

Italy
Aristotle University Of Thessaloniki

Not yet recruiting

Intravascular ULTRAsound-Guided PCI in Patients With ST-Elevation Myocardial Infarction (ULTRA-STEMI)

STEMI | IVUS | Intravascular Imaging
Shockwave Medical, Inc.

Recruiting

Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)

Myocardial Infarction | Coronary Artery Disease

United States
Kyungpook National University Chilgok Hospital

Recruiting

A Comparison of Intravascular Penetration With Curved Needle and Straight Needle During S1 STE

S1 Transforaminal Epidural Injection

Korea, Republic of

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