Search clinical trials for: mechanisms of change

Total 428618 results

AbbVie

Recruiting

A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants

Masseter Muscle Prominence

United States
Nimble Science Ltd.

Not yet recruiting

The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule

Nutrition | Microtia | Amino Acid Change | Food Science | Digestion Rate

Canada
AbbVie

Recruiting

A Study to Assess BOTOX Injections in Adult Participants for the Change of Masseter Muscle Prominence

Masseter Muscle Prominence

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

ORal Antibiotics In Acute Mesenteric Ischemia (ORIAMI)

Acute Mesenteric Ischemia

France
Murdoch Childrens Research Institute

Not yet recruiting

A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma. (PEGASUS)

Hodgkin Lymphoma | Non Hodgkin Lymphoma

Australia
AstraZeneca

Not yet recruiting

Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD (COnCORD)

Chronic Obstructive Pulmonary Disease (COPD)
University Hospital Tuebingen
German Research Foundation; Uppsala University

Not yet recruiting

Dopamine, Reward Learning and Sex Hormones

Menstrual Cycle | Hormonal Changes

Germany
St. Mary's Research Center, Canada
Sunnybrook Health Sciences Centre; University of British Columbia; McGill University and other collaborators

Not yet recruiting

A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers

Anxiety | Cancer of the Prostate

Canada
University of Chicago

Not yet recruiting

Assessing the Efficacy and Safety of Anti-HER2 Therapy in Nigerian Women With HER2+ Breast Cancer Before and After Surgery

Breast Cancer | HER2-positive Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

United States
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
Kirby Institute

Not yet recruiting

Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART) (OPTIMAR)

HIV Infections | Weight Gain
Applied Science & Performance Institute

Recruiting

The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States

Cognitive Change | Mood Change | Mental Processes

United States
Centre Hospitalier Universitaire Vaudois
Unisanté Centre universitaire de médecine générale et santé publique; FORCE...

Not yet recruiting

Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance (DAR-ARC)

Febrile Neutropenia

Switzerland
The Cleveland Clinic

Recruiting

Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor (TRaNCE)

Essential Tremor

United States
Rajavithi Hospital

Not yet recruiting

Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer With Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial

Weight Gain
Aristotle University Of Thessaloniki

Recruiting

Empagliflozin and Red Blood Cell 2,3-biphosphoglycerate Levels

Cardiovascular Prevention | Tissue Oxygenation | Empagliflozin | SGLT2-Inhibitors | Hematocrit Change

Greece
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant

Healthy

United States
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam

Healthy Participants

Belgium
AbbVie

Recruiting

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (LIVIGNO-4)

Non-Small Cell Lung Cancer

United States, Israel, Japan
Bernhard Nocht Institute for Tropical Medicine

Not yet recruiting

LAssa Fever Adjunct Treatment With DEXamethasone (LADEX)

Lassa Fever
Irrua Specialist Teaching Hospital
University of Bordeaux; Médecins Sans Frontières, Belgium; ANRS, Emerging Infectious... and other collaborators

Not yet recruiting

ISTH/ANRS 0409s INTEGRATE Lassa Fever Study

Lassa Fever
AbbVie
Genmab

Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma (EPCORE™FL-2)

Follicular Lymphoma (FL)

United States, Puerto Rico
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

A Study of Niacin Regulation

Excessive Weight Gain

United States
National Cancer Institute (NCI)

Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Neuroblastoma | Ganglioneuroblastoma

United States
AbbVie

Recruiting

A Study to Assess Adverse Events and Change of Masseter Muscle Prominence Using BOTOX Injections in Adult Participants

Masseter Muscle Prominence

Japan
Eli Lilly and Company
Loxo Oncology, Inc.

Recruiting

A Study of LY3537982 Plus Immunotherapy With or Without Chemotherapy in Participants With Non-Small Cell Lung Cancer (NSCLC) With a Change in a Gene Called KRAS G12C (SUNRAY-01)

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis

United States, Taiwan, Belgium, Australia, Japan, United Kingdom, Spain, China, France, Germany, Austria, Korea, Republic of, Hungary, Switzerland, Turkey, Mexico, Norway, Italy, Portugal, Netherlands, India, Romania, Canada, Denmark, G... and more
AbbVie

Recruiting

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-2)

Hepatocellular Carcinoma

United States, Taiwan
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

Unresectable Metastatic Colorectal Cancer

Israel, United States, Japan, Korea, Republic of, Taiwan
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Whether Participants With Melanoma Prefer Subcutaneous vs Intravenous Administration of Nivolumab and Nivolumab + Relatlimab Fixed-dose Combinations

Melanoma

Spain, United States, Italy, Chile, Greece, Argentina
Hematology Oncology Associates of Central New York

Not yet recruiting

PFA 100 Evaluation and Reference Interval HOACNY

Effect of Drug
AbbVie

Not yet recruiting

Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein

Non-Small Cell Lung Cancer
Zhejiang Cancer Hospital
Wenzhou Medical University; Xijing Hospital; Shanxi Province Cancer Hospital; The... and other collaborators

Recruiting

Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms

Gastric Cancer | Diagnosis | Tongue Images

China
AbbVie

Recruiting

A Study to Assess the Effectiveness of BOTOX (Botulinum Toxin Type A) Injections for the Change of Masseter Muscle Prominence in Adult Participants

Masseter Muscle Prominence

Bulgaria, Germany, Spain, Italy, United Kingdom, Belgium, France
University of California, San Francisco

Not yet recruiting

Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy (ReINFORCE)

Demyelinating Diseases | Clinically Isolated Syndrome, CNS Demyelinating | Multiple Sclerosis Brain Lesion | Multiple Sclerosis Acute and Progressive | Demyelination; Corpus Callosum

United States
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Step by Step Group Therapy for Bulimia Nervosa: Effectiveness and Mechanisms of Change. (SBSBN)

Bulimia Nervosa

Spain
Ankara City Hospital Bilkent

Recruiting

Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients

Sepsis | Fever | Acetaminophen | Ibuprofen

Turkey
National Cancer Institute (NCI)

Recruiting

Durvalumab With Gemcitabine and Cisplatin for the Treatment of High Risk Resectable Liver Cancer Before Surgery

Intrahepatic Cholangiocarcinoma

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Recurrent Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8 | Metastatic Nasopharyngeal Carcinoma

United States, China
Yale University
National Cancer Institute (NCI)

Recruiting

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use

Smoking Cessation | Cigarette Smoking | E-Cigarette Use

United States
Tanta University

Recruiting

Preoperative Nebulized Dexmedetomidine on Hemodynamic Changes in Laparoscopic Bariatric Surgery.

Dexmedetomidine | Hemodynamics | Laparoscopic Bariatric Surgery

Egypt
Chang Gung Memorial Hospital

Recruiting

CSF Metabolomics and Glymphatic Function in Patients Receiving VP- Shunt Surgery.

The Association of Postoperative Cognitive Dysfunction With Glymphatic Function and Neuroinflammation | The Association of Postoperative Cognitive Dysfunction With CSF Metabolomic Change

Taiwan
Lithuanian University of Health Sciences
Research Council of Lithuania

Recruiting

The Effect of Combined Cryotherapy and Immunotherapy on Systemic T Cell Changes and Clinical Outcomes in Metastatic Non-small Cell Lung Cancer (LUCACRIMUNO)

Lung Cancer Stage IV

Lithuania
Oman Ministry of Health

Not yet recruiting

The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes (DAPA-ANDO)

Obesity | Weight Loss | Effect of Drug | Dapagliflozin Adverse Reaction
Queen Mary University of London
University of Washington; University of Oxford; KEMRI-Wellcome Trust Collaborative... and other collaborators

Not yet recruiting

An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM (Co-SAM)

HIV | Severe Acute Malnutrition | Comorbidities and Coexisting Conditions | Child Malnutrition
Peking University First Hospital
Aerospace Center Hospital

Recruiting

Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC

Postoperative Complications | Acute Kidney Injury | Cytoreductive Surgery | Hydration | Diuresis | Hyperthermic Intraperitoneal Chemotherapy

China
Weill Medical College of Cornell University
National Institute of Mental Health (NIMH)

Recruiting

Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality

Depressive Disorder | Depression | Suicidal Ideation | Major Depressive Disorder

United States
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Weight Loss Study: Genetics and Response to Naltrexone/Bupropion

Obesity

United States
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (Step-Up HS)

Hidradenitis Suppurativa

United States, Japan, Australia, Canada, Korea, Republic of, New Zealand, Puerto Rico, Spain, Taiwan, Austria, Italy, Bulgaria, Israel, Croatia, Hungary, Netherlands, Switzerland, Germany, Portugal, France, United Kingdom, Czechia, ... and more
Semmelweis University

Recruiting

Neoadjuvant Concomitant Modulated Electro-hyperthermia in HER2-negative Breast Cancer (NeoHTerMa)

HER2-negative Breast Cancer

Hungary

Search clinical trials for: mechanisms of change

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