Search clinical trials for: minimum effective dose of local anaesthetic

Total 437954 results

Cork University Hospital

Completed

Minimum Effective Intrathecal Dose of Local Anaesthetic With Fentanyl for Fractured Neck of Femur(Dose Finding Study).

Minimum Effective Dose of Local Anaesthetic With Fentanyl

Ireland
Mogilev Regional Clinical Hospital

Recruiting

Femoral Nerve Blockade 7.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Femoral Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.). (EPBwEPN)

Ultrasonography | Nerve Block | Efficiency | Femoral Nerve | Minimum Effective Dose

Belarus
Mogilev Regional Clinical Hospital

Completed

Sciatic Nerve Blockade by Subgluteal Access 12.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Sciatic Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.). (EPBwEPN)

Ultrasonography | Sciatic Nerve | Nerve Block | Efficiency | Minimum Effective Dose

Belarus
Shanghai 6th People's Hospital

Completed

Minimum Effective Dose of Ropivacaine for Spinal Anesthesia for Cesarean Delivery

Spinal Anesthesia

China
University of Leeds
National Institute of Academic Anaesthesia (NIAA), UK; Obstetric Anaethetists...

Unknown

Minimum Effective Dose (MED) & Epidural Bupivacaine

Pregnancy | Labour | Epidural Block | Primigravida Labour

United Kingdom
Sunnybrook Health Sciences Centre

Unknown

Effects of Technique on the Local Anesthetic Dose Required for Interscalene Brachial Plexus Block

Arthroscopic Shoulder Surgery

Canada
Samuel Lunenfeld Research Institute, Mount Sinai...

Completed

Minimum Local Anesthetic Volume of Bupivacaine in Labour Epidurals

Acute Pain

Canada
Second Hospital of Shanxi Medical University

Recruiting

the 95% Effective Dose of Ciprofol for Adjunctive Sedation Undergoing Knee Arthroplasty in Elderly People

Knee Arthroplasty | Sedation | ED95

China
Juno Therapeutics, Inc., a Bristol-Myers Squibb...

Recruiting

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States
Benaroya Research Institute

Recruiting

Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block

Post Operative Pain

United States
Pfizer

Recruiting

A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway. (DELINOR)

Non-Small Cell Lung Cancer

Norway
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)

Anatomic Stage IV Breast Cancer AJCC v8 | Chemotherapy-Induced Peripheral Neuropathy | Metastatic Breast Carcinoma

United States
Pusan National University Hospital
Yuhan Corporation

Not yet recruiting

Impact of Lazertinib Dose Modification on Effectiveness and Safety

Non-small Cell Lung Cancer

Korea, Republic of
Peking University
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Effectiveness of Cryotherapy Combined With Compression Therapy for Preventing Chemotherapy-induced Peripheral Neuropathy

Breast Cancer

China
Far Eastern Memorial Hospital

Recruiting

The Minimum Effective Concentration of Lidocaine for Ultrasound-guided Axillary Block for Arterio-venous Fistula Creation Surgery

Anesthesia

Taiwan
Peking Union Medical College Hospital

Not yet recruiting

The MEV of 0.5% Ropivacaine in Ultrasound-guided SASIS-FICB (SASIS-FICB)

Nerve Block

China
Chinese University of Hong Kong

Recruiting

Minimum Effective Local Anesthetic Volume for Ultrasound Guided Superior Trunk Block

Musculoskeletal Diseases or Conditions

Hong Kong
Assiut University

Recruiting

Could Peri-anal Block be Effective as Caudal Block in Trans-anal Pull-through Surgery ??.

Analgesia

Egypt
National Cancer Institute (NCI)

Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Colorectal Neoplasms | Advanced Breast Cancer | Advanced Solid Tumors | Malignant Peripheral Nerve Sheath Tumor | Metastatic Pancreatic Cancer | Pediatric Solid Tumor

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Unresectable Intrahepatic Cholangiocarcinoma

United States
Boehringer Ingelheim

Active, not recruiting

This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer.

Neoplasms | Breast Neoplasms

United States, Spain, Korea, Republic of, Finland, Japan, Denmark, France
Second Hospital of Shanxi Medical University

Completed

Median Effective Dose of Ciprofol-Assisted Sedation for Elderly Patients Undergoing Knee Arthroplasty

Knee Arthroplasty | Sedation | ED50

China
OBI Pharma, Inc

Terminated

This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.

Locally Advanced Solid Tumors | Metastatic Solid Tumors

United States, Taiwan
Boehringer Ingelheim

Completed

A Study to Find a Safe and Effective Dose of BI 905711 in Patients With Advanced Gastrointestinal Cancer

Gastrointestinal Neoplasms | Pancreatic Neoplasms | Cholangiocarcinoma

Spain, Belgium, China, United States, Germany, Korea, Republic of, France, Japan
VA Office of Research and Development

Active, not recruiting

Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens

Colorectal Cancer

United States
Merck Sharp & Dohme LLC

Terminated

To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Participants With Advanced Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Anemia | Bladder Cancer | Cancer of Head and Neck | Uterine Cervical Cancer | Carcinoma, Small-Cell Lung
University Hospital, Toulouse

Completed

Analgesic Effectiveness of PENG Block in Programmed Hip Arthroplasty Surgery (THAPeng)

Postoperative Pain

France
University of Alberta

Enrolling by invitation

MinMed: Do Older Adults do Better With Less Medication

Frailty | Aging | Adverse Drug Interaction

Canada
Queen Mary University of London
Cancer Research UK; Barts and the London School of Medicine and Dentistry

Completed

A Study to Examine the Effectiveness of Aspirin and/or Vitamin D3 to Prevent Prostate Cancer Progression (PROVENT)

Prostate Cancer

United Kingdom
Shiyou Wei

Completed

95% Effective Dose(ED95) of Remimazolam During Dexmedetomidine Pretreatment

Lung Cancer | Anesthesia Induction

China
University Hospital, Ghent

Completed

Determination of the Minimum Local Analgesic Dose of Spinal Chloroprocaine in Labour

Pain Relief During Labour

Belgium
Alexandria University

Active, not recruiting

Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection

Local Anesthesia

Egypt
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma

Neuroblastoma

United States
Bayer

Completed

Effectiveness of Low Dose Aspirin in Decreasing the Chance Getting Stomach and Intestine Cancer (ENgAGE-HK)

Gastrointestinal Cancer

Hong Kong
Chinese University of Hong Kong

Completed

Minimum Effective Volume for Selective Trunk Block

Musculoskeletal Diseases or Conditions

Hong Kong
M.D. Anderson Cancer Center

Completed

A Randomized Trial Evaluating Rapid Delivery of Dose Escalated Hypofractionated Radiotherapy for Patients Diagnosed With Bone Metastases for Effective Palliation of Symptoms

Bone Metastases

United States
Ankara City Hospital Bilkent

Completed

Determination of Minimum Effective Volume of Local Anesthetic in Patients Undergoing Ultrasound-Guided Infraclavicular Approach for Brachial Plexus Blockade

Physiological Effects of Drugs | Peripheral Nervous System Agents | Anesthetics, Local | Underdosing of Local Anesthetics
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 2 Trial of Rebamipide Liquid to Determine the Effective Dose for Prevention of Chemoradiotherapy-induced Oral Mucositis in Patients With Head and Neck Cancer

Head and Neck Cancer

Japan
West China Hospital

Terminated

Effective Study of Preoperative Short-course Radiotherapy for the Advanced Resectable Rectal Cancer

Rectal Neoplasms

China
Bayer

Terminated

Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 When Given Together With Chemotherapy and the Effectiveness of This Combination Treatment in Shrinking a Specific Type of Lung Tumors (Small Cell Lung Cancer)

Small Cell Lung Carcinoma

United States, Korea, Republic of, France
Prisma Health-Upstate
Albert Einstein College of Medicine; Clemson University

Completed

Intensive Models of HCV Care for Injection Drug Users

Hepatitis C | Medication Adherence

United States
Legacy Health System

Completed

Effectiveness of High Dose Vitamin D Supplementation in Stage III Colorectal Cancer

Rectal Cancer | Colon Cancer

United States
Bayer

Completed

EffectiveNess of Low Dose Aspirin in GastrointEstinal Cancer Prevention - Taiwan (ENgAGE-Taiwan)

Colorectal Neoplasms

Taiwan
University Medicine Greifswald

Completed

Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treatment

Dental Caries

Germany
Bayer

Completed

EffectiveNess of Low-dose Aspirin in Prevention of Cancer in the Stomach and Oesophagus (GastrointEstinal Cancer Prevention) - United Kingdom ("ENgAGE - UK"): Study to Evaluate the Risk of Cancer in the Stomach and Oesophagus Among New Users of Low-dose Aspirin Using the THIN Database in the UK (ENgAGE-UK)

Prevention of Oesophagus Cancer and Stomach Cancer

United Kingdom
Shandong Golden Brick Biotechnology Co., Ltd.

Unknown

Study on the Safety and Effectiveness of UCB-NK Cell Infusion in the Treatment of Advanced Gastric Cancer and Gastroesophageal Cancer

Advanced Gastric Cancer | Gastroesophageal Cancer

China
Yangzhou University

Completed

Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated With Medium-/Long-chain Triglycerides

Lidocaine | Injection Pain

China
Ankara City Hospital Bilkent

Completed

Minimum Effective Volume Of Local Anesthetic İn USG Guided Axillary Approach Brachial Plexus Block

Underdosing of Local Anesthetics
Zealand University Hospital

Unknown

The Minimal Effective Volume (MEV90) of Ropivacaine 0.75% for Ultrasound-guided Transmuscular Quadratus Lumborum Block

Percutaneous Nephrolithotomy
Ain Shams University

Completed

Minimum Effective Volume of Local Anesthetic for Peribulbar Block.Does it Differ With the Eyeball Axial Length?

Peribulbar Block

Egypt

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