Search clinical trials for: nifedipine gastrointestinal therapeutic system (GITS)

Total 256109 results

Bayer

Completed

Open-Label Long-Term Safety and Efficacy Study of Fixed Dose Combination of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Subjects With Moderate to Severe Essential Hypertension

Hypertension

Germany, United States, Canada, Poland, United Kingdom, Belgium
Bayer

Withdrawn

Monotherapy-Controlled Study of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Combination in Subjects With Essential Hypertension Inadequately Controlled on Candesartan Cilexetil

Hypertension

Italy
Jing Liu
Bayer

Terminated

Nifedipine GITS and Amlodipine Besylate on Recovery of Blood Pressure Rhythm and Arterial Stiffness (NARRAS)

Hypertension

China
Bayer

Completed

Low-dose Nifedipine-Valsartan Combination Compared to Up-titrated Valsartan Monotherapy in Essential Hypertension

Hypertension

China, Korea, Republic of
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Post Marketing Surveillance Study Of Doxazosin Mesylate GITS Among Filipino Patients With Benign Prostatic Hyperplasia (BPH)

Prostatic Hyperplasia

Philippines
Pfizer

Completed

Bioequivalence Study Of Glucotrol XL 2.5 Mg Tablets

Hyperglycemia | Diabetes Mellitus, Non-Insulin-Dependent

Singapore
Bayer

Completed

Study Evaluating the Efficacy of Nifedipine GITS - Telmisartan Combination in Blood Pressure Control.

Hypertension

Italy, Spain
Bayer

Completed

Effectiveness and Tolerability of Long-Acting Nifedipine Gastrointestinal Therapeutic System in Chronic Kidney Disease With Uncontrolled Hypertension Patients, a Prospective, Multicenter, Observational Study (ADRENAL)

Hypertension

China
Eli Lilly and Company
National Institute of Allergy and Infectious Diseases (NIAID); Shanghai Junshi... and other collaborators

Completed

A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff (BLAZE-2)

COVID-19 | SARS-CoV2

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Evaluation Of The Efficacy And Safety Of The Doxasozin Gastrointestinal Therapeutic System (GITS) In Patients With Prostate Enlargement

Prostate

Taiwan
Bayer

Completed

Study of Nifedipine GITS and Candesartan Combination Compared to Monotherapy in Patients With Essential Hypertension (DISTINCT)

Hypertension, Essential

Spain, Argentina, United States, Canada, Korea, Republic of, Italy, Russian Federation, South Africa, Ukraine, Belgium, Brazil, Lithuania, United Kingdom
Istituto Auxologico Italiano
Bayer

Completed

REducing Blood Pressure Variability in Essential Hypertension With RAmipril vErsus Nifedipine GITS Trial (REVERENT)

Hypertension | High Blood Pressure Variability

China, Greece, Italy
Shanghai Jiao Tong University School of Medicine

Completed

Amlodipine Prevents Morning Blood Pressure Surge Study (ARMORS)

Hypertension

China
Peking University First Hospital
Bayer

Unknown

Effect of Nifedipine GITS in Patients With Mild-to-moderate Primary Hypertension

Hypertension

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Effects of Doxazosin Gastrointestinal Therapeutic System on Ambulatory Blood Pressure and Cardiovascular Risk Factors in Uncontrolled Hypertensive Patients

Hypertension

Spain, Italy, United Kingdom
Bayer

Completed

Single Dose Escalation Study to Investigate the Pharmacokinetics as Well as Safety and Tolerability of a Concomitant Administration of Nifedipne GITS and Candesartan Tablets Under Fasting Conditions in Healthy Male Subjects in an Open Label, Non-randomized, Sequential Design.

Clinical Pharmacology

Germany
Hospital Authority, Hong Kong

Completed

Effect of Vardenafil on Blood Pressure in Patients With Erectile Dysfunction Who Received Concomitant Doxazosin GITS

Prostatic Hyperplasia | Impotence

China
Bayer

Completed

Single Dose Bioequivalence Study Comparing Nifedipine/Candesartan FDC (Fixed Dose Combination) With Loose Combination of Nifedipine GITS (Gastro-intestinal Therapeutic System) Plus Candesartan and Single Components Under Fasting Conditions

Hypertension, Essential

Germany
Bayer

Completed

Blood Pressure Control of Nifedipine GITS 60mg Treatment in Chinese Hypertensive Subjects Uncontrolled on Starting-dose Mono-therapyo-therapy. (ADEPT)

Hypertension

China
National Taiwan University Hospital

Unknown

A Study of Nifecardia SRFC and Adalat OROS in the Treatment of Patients With Essential Hypertension

Hypertension

Taiwan
Cao Yu

Unknown

Bioequivalence of Extended Release Nifedipine Tablets in Healthy Chinese Subjects

Therapeutic Equivalency

China
SocraTec R&D GmbH
SocraMetrics GmbH

Completed

Nifedipine Bioavailability Study With Oral Single Doses Under Fasting and Fed Conditions

Bioavailability, Therapeutical Indication Not Studied

Germany
Hospital Authority, Hong Kong

Terminated

Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up

Prostatic Hyperplasia | Urinary Retention

China
Guangzhou First People's Hospital

Unknown

The Pharmacokinetics of Nifedipine Controlled Release Tablets in Hypertensive Patients on Hemodialysis (PICASSO)

Hypertension on Chronic Maintenance Hemodialysis

China
Hospital Authority, Hong Kong

Terminated

Randomized Trial Comparing Alfuzosin GITS 10 mg Daily With Placebo for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up

Prostatic Hyperplasia | Acute Disease | Urinary Retention

China
Northern Jiangsu People's Hospital

Recruiting

Comparative Analysis of Short-Term Therapeutic Effects Between the π-Shaped and Overlap Methods for Esophagogastrostomy in Totally Laparoscopic Total Gastrectomy

Gastric Cancer

China
MedSIR
Stemline Therapeutics, Inc.

Not yet recruiting

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (ADELA)

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation
Shanghai Juncell Therapeutics

Not yet recruiting

Engineering Tumor Infiltrating Lymphocytes Injection (GC203 TIL) for the Treatment of Advanced Malignant Solid Tumors (KUNLUN-001)

Breast Cancer | Gynecologic Cancer | Lung Cancer | Solid Tumor | Gastrointestinal Cancer
National Institute of Allergy and Infectious Diseases...

Recruiting

Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.

HIV

United States
Daping Hospital and the Research Institute of Surgery...

Recruiting

The Therapeutic Efficacy of 18F-FDG Combined With 18F-FAPI PET/MR in Neoadjuvant Therapy for Gastric Cancer

Cancer

China
Enliven Therapeutics

Recruiting

ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer

Colorectal Cancer | HER2-positive Breast Cancer | HER2-positive Gastric Cancer | HER2 Amplification | HER2 Positive Solid Tumors

United States
Mozart Therapeutics Australia Pty Ltd

Not yet recruiting

Safety, Pharmacokinetics, and Pharmacodynamics of MTX-101 in Healthy Adults and Patients

Type 1 Diabetes | Celiac Disease | Healthy Volunteers

Australia
Gut-Brain-Axis Therapeutics Inc.
Pitt Hopkins Research Foundation

Recruiting

Microbiota Transfer Therapy for Children and Adults With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders

Pitt Hopkins Syndrome

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

B Acute Lymphoblastic Leukemia | Acute Leukemia of Ambiguous Lineage
Xuanwu Hospital, Beijing

Recruiting

The Therapeutic Effect of Betaine in Syringomyelia

Syringomyelia

China
China Medical University, China
Beijing Bio-Targeting Therapeutics Technology Co., Ltd

Not yet recruiting

A Clinical Study of BioTTT001 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer

Colorectal Cancer Metastatic
China Medical University, China
Beijing Bio-Targeting Therapeutics Technology Co., Ltd

Not yet recruiting

A Clinical Study of BioTTT001 in Combination With SOX and Toripalimab in Patients With Gastric Cancer

Gastric Cancer, Metastatic
NiKang Therapeutics, Inc.

Recruiting

A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors

Small Cell Lung Carcinoma | Gastric Cancer | Ovarian Neoplasms | Ovarian Cancer | Solid Tumor | Endometrial Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Solid... and other conditions

United States
Hospices Civils de Lyon
Centre International de Recherche en Infectiologie (CIRI)

Not yet recruiting

TOward a Better Understanding of the autoPhagy Machinery for the Identification of Potential Novel Biomarkers and Therapeutic Targets in Crohn's Disease - TOPIC Study (TOPIC)

Crohn's Disease

France
Merck Sharp & Dohme LLC

Recruiting

Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Israel, United States, Australia
Morphic Therapeutic, Inc

Recruiting

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

Inflammatory Bowel Diseases | Crohn's Disease

United States
First People's Hospital of Hangzhou
Macera therapeutics

Not yet recruiting

Human HER2-targeted Macrophages Therapy for HER2-positive Advanced Gastric Cancer With Peritoneal Metastases

Gastric Cancer

China
Neogene Therapeutics, Inc.

Recruiting

A Study of NT-112 in HLA-C*08:02-Positive Adult Subjects With Unresectable, Advanced, and/ or Metastatic Solid Tumors Positive for the KRAS G12D Mutation

Endometrial Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Colorectal Carcinoma | Solid Tumor, Adult | KRAS G12D

United States
Universiti Sains Malaysia
Ministry of Higher Education, Malaysia

Recruiting

Elucidating Mechanisms That Underlie the Symptomatology of Functional Dyspepsia Using Novel Techniques and Its Therapeutic Validation Using Neuromodulators

Healthy | Functional Disorder of Stomach

Malaysia
Odyssey Therapeutics

Recruiting

Phase 1 Study to Investigate OD-07656 in Healthy Adult Participants

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Spondyloarthritis | Blau Syndrome

Australia
TRYP Therapeutics

Recruiting

Assessment of Psilocybin (TRP-8802) in Concert With Psychotherapy in Patients With Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome

United States
Zhang Xiaofeng,MD
Zeno Therapeutics Pte. Ltd

Not yet recruiting

Early Phase I Study of Autologous T Cells (EX02 CAR-T) for Unresectable Pancreatic/Bile Duct Cancer

Pancreatic Cancer | Advanced Biliary Cancer
Stichting European Myeloma Network
Janssen Pharmaceutica

Recruiting

Phase 2 Study Applying MRD Techniques for Participants With Previously Untreated Multiple Myeloma Treated With D-VRd Prior To and After High-dose Therapy Followed by ASCT - TAURUS (TAURUS)

Multiple Myeloma

Austria, Greece, Italy, Netherlands, Germany
Centre Hospitalier Universitaire de Saint Etienne
Takeda France

Not yet recruiting

Comparison of Vedolizumab Treatment to Adalimumab Dose Intensification in Crohn's Disease Patients With Loss of Response or Biomarker Activity to Adalimumab on First Line With Therapeutic Drug Concentration. (VEDIAN)

Crohn's Disease

France
National Cancer Institute (NCI)

Recruiting

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

Metastatic Colorectal Cancer

United States

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