Search clinical trials for: ophthalmic delivery

Total 6237 results

Visualiza
Seva Foundation

Not yet recruiting

Safety and Effectiveness of Drop-free Small Incision Cataract Surgery

Ocular Hypertension | Ocular Inflammation | Cataract | Post-Op Complication
Hoffmann-La Roche

Recruiting

Extension Study for the Port Delivery System With Ranibizumab (Portal) (Portal)

Neovascular Age-Related Macular Degeneration

Belgium, United States, United Kingdom, Italy, Argentina, Spain, Israel, Australia, Austria, Brazil, Germany, Switzerland, Taiwan, France
Hoffmann-La Roche

Active, not recruiting

This Study Will Evaluate the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System With Ranibizumab in Participants With Diabetic Macular Edema Compared With Intravitreal Ranibizumab (Pagoda)

Diabetic Macular Edema

United States
Stealth BioTherapeutics Inc.

Completed

ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA (ReCLAIM-2)

Age-related Macular Degeneration

United States
Cathleen McCabe MD
Ocular Therapeutix, Inc.

Terminated

Clinical Investigation of the Dextenza 0.4mg Intracanalicular Insert Delivery System Used in Cataract Surgery

Cataract

United States
Hoffmann-La Roche

Completed

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration (Archway)

Neovascular Age-Related Macular Degeneration

United States
Mati Therapeutics Inc.

Completed

Safety/Efficacy of Nepafenac Punctal Plug Delivery System Compared to Placebo to Control Ocular Pain/Inflammation After Cataract

Pain | Inflammation

United States
Shire

Completed

A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE)

Dry Eye

United States
Shire

Completed

Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1) (OPUS-1)

Keratoconjunctivitis Sicca | Dry Eye Disease

United States
Genentech, Inc.

Completed

Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degeneration (LADDER)

Macular Degeneration

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Withdrawn

Safety And Efficacy Of Xalatan Delivered Using Either A Conventional Dropper Bottle or A Delivery Device

Ocular Hypertension | Glaucoma, Open-Angle
Pfizer's Upjohn has merged with Mylan to form Viatris...

Withdrawn

Corneal Versus Conjunctival Delivery Using a Delivery Device

Ocular Hypertension | Glaucoma, Open-Angle
Shahid Beheshti University of Medical Sciences

Unknown

The Additional Role of Supplemental Oxygen Therapy in Accelerated Corneal Collagen Cross-linking in Progressive Keratoconus. A Randomized Clinical Trial

Keratoconus

Iran, Islamic Republic of
National Eye Institute (NEI)

Terminated

Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)

Inherited Retinal Degeneration | Inherited Ophthalmic Diseases

United States
Allergan

Completed

Investigation of Maintaining Visual Performance Achieved With Cyclosporine Therapy (IMPACT)

Dry Eye Syndromes

United States
Eyegate Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL

Cataract

United States
Calhoun Vision, Inc.

Completed

Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism

Cataract

United States
Shaare Zedek Medical Center

Unknown

Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LP (EXP-LP)

Ocular Hypertension | Glaucoma | IOP

Israel
Mati Therapeutics Inc.

Completed

A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Open-Angle Glaucoma

United States
John Kempen

Completed

Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study

Non-infectious, Non-necrotizing Anterior Scleritis

United States
Mati Therapeutics Inc.
QLT Inc.

Completed

A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG

Ocular Hypertension | Open-Angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Mati Therapeutics Inc.

Completed

Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertension (CORE)

Ocular Hypertension | Glaucoma

United States
Mati Therapeutics Inc.

Completed

Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
Mati Therapeutics Inc.
QLT Inc.

Completed

A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

Ocular Hypertension | Open-Angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Open Angle Glaucoma

Canada
Mati Therapeutics Inc.

Completed

A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
Mati Therapeutics Inc.

Withdrawn

A Phase 2 Study of the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Glaucoma
Pfizer

Completed

Study Comparing Perceptions and Satisfaction for Two Different Delivery Mechanisms for Etanercept

Rheumatoid Arthritis

France, Germany, Italy, Sweden, United Kingdom, Netherlands, Denmark, Finland, Norway
Alcon Research

Completed

Safety/Efficacy of Systane Free vs Refresh Liquigel

Dry Eye
Alcon Research

Completed

Acute Comfort of Lubricant Eye Drops FID 112903

Dry Eye

United States
Alcon Research

Completed

Evaluation of the Repeated Usage of Systane Ultra Eyedrop

Dry Eye
Eyegate Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of EGP-437 (Dexamethasone Phosphate Formulated for Ocular Iontophoresis) to Treat Dry Eye

Dry Eye

United States
Eyegate Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye

Dry Eye Syndrome

United States
Medical University of Vienna

Not yet recruiting

Personalized Shared Eye-care Identification of Age-related Macular Degeneration Using Artificial Intelligence and Telemedicine in a Prospective, Exploratory, Multinational, Multicentre Cross-sectional Study Matching Optometrist Office-based Sites With Clinical Supervision (PYRENEES)

Age-Related Macular Degeneration
Imperial College London

Not yet recruiting

Automated Insulin Delivery in Adults With Advanced Kidney Disease (AIDkidney)

Diabetes Mellitus | Chronic Kidney Diseases
CHU de Reims

Recruiting

Feeling of Caregivers After a Palliative Management of Extreme Premature Babies in Delivery Room.

Caregiver Feeling

France
MicroPort CRM

Not yet recruiting

Safety and Performance Evaluation of a New Catheter Range for Lead Implantation at Interventricular Septum (POLARIS)

Bradycardia | Cardiac Resynchronization Therapy | Left Bundle Branch Area Pacing
Darell Bigner
Rockefeller University

Not yet recruiting

D2C7-IT + 2141-V11 Combination Post-rection in rGBM - Phase 1b

Recurrent Glioblastoma IDH Wildtype

United States
Lokman Hekim Üniversitesi

Not yet recruiting

The Effect of Spouse Participation Childbirth Preparation Program on Birth Outcomes

Fear of Childbirth | Mode of Delivery | Childbirth Self-Efficacy | Childbirth Preparation Program

Turkey
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia

Presbyopia
Claris Biotherapeutics, Inc.

Recruiting

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency

Limbal Stem Cell Deficiency

United States
Jaeb Center for Health Research
Massachusetts General Hospital; Cystic Fibrosis Foundation; Beta Bionics, Inc.

Not yet recruiting

Bionic Pancreas in CFRD

Cystic Fibrosis-related Diabetes
Ohio State University

Not yet recruiting

Changes in Eye Shape With Myopia Management Interventions

Myopia
Alcon Research

Not yet recruiting

A Double-Masked Comparison of FID 123320 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness

Ocular Redness

United States
AbbVie

Recruiting

An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
RAND
Innovations for Poverty Action; Clinton Health Access Initiative, Nigeria

Not yet recruiting

The Impact of Pre-emptive Home Delivery of ORS + Zinc on Treatment for Child Diarrhea

Diarrhea Toddler
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

TRESPASS Clinical Study

Perineal Laceration, Tear, or Rupture During Delivery

Italy
Fudan University

Not yet recruiting

Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma，Bispecific Antibodies, HAIC, Ramucirumab

China

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