Search clinical trials for: organ damage

Total 62171 results

Canadian Cancer Trials Group
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes (OPTION-DDR)

Metastatic Prostate Cancer | Metastatic Castration-resistant Prostate Cancer
Novo Nordisk A/S

Recruiting

Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease

Alcohol-related Liver Disease

Czechia, Denmark, Italy, Netherlands, Canada, Spain, United States, Australia, Japan, Greece, France, Poland, Bulgaria, Germany
Rigshospitalet, Denmark

Not yet recruiting

Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention (TRALULALA-AZI)

Bronchiectasis | Bronchopulmonary Dysplasia (BPD) | Tracheomalacia | Cystic Lung Disease | Vascular Ring | Chronic Atelectasis
Kolding Sygehus
Odense University Hospital; Vejle Hospital

Recruiting

The Role of Proprotein-convertase-subtilisin/Kexin-type 9 in Kidney Damage in Nephrotic Syndrom (PCSK9)

Hyperlipidemias | Nephrotic Syndrome

Denmark
Complejo Hospitalario Universitario de Santiago
Instituto de Salud Carlos III; University of Santiago de Compostela; Instituto... and other collaborators

Recruiting

Glycoxidation, Arterial Biomechanics, and Target Organ Damage (GlycOxiTod)

Oxidative Stress | Cardiovascular Risk | Target Organ Damage

Spain
Sohag University

Recruiting

The 2019 EULAR/ACR Classification Criteria as Predictor of Organ Damage in Systemic Lupus Erythematosus Patients

SLE, and Organ Damage Index

Egypt
Ankara City Hospital Bilkent

Recruiting

Evaluation of Kidney Damage Using NGAL Measurements

Prostatectomy | Kidney Function Tests | Neutrophil Gelatinase-Associated Lipocalin

Turkey
Third Military Medical University

Recruiting

The Predictive Value of 24-hour Urinary Aldosterone on Target Organ Damage

Hypertension | Primary Aldosteronism

China
Istituto Giannina Gaslini
Eubrain

Recruiting

A Randomized Controlled Trial to Evaluate the Effect of White Noises and Parental Voices as Protectors Against Noise Damage in a Neonatal Intensive Care Unit

Premature Infant Disease

Italy
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function

Sickle Cell Disease

United States
Novo Nordisk A/S

Recruiting

A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo

Obesity | Type 2 Diabetes | Chronic Kidney Disease

United States, Spain, Poland, Thailand, India, France, Argentina, Canada, Japan, Greece, Slovakia, Hungary, Brazil
University Hospital, Geneva

Recruiting

Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants (BAMBI)

Nervous System Diseases | Cerebral Palsy | Brain Injuries | Premature Birth | Neurodevelopmental Disorders

Switzerland
Marianne Barbu-Roth
Assistance Publique - Hôpitaux de Paris; San Francisco State University; Ecole... and other collaborators

Recruiting

Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder (Premalocom2)

Prematurity | Brain Damage | Infant Development | Extreme Prematurity | Motor and Developmental Delay

France
Alexandria University

Recruiting

Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity

Nerve Degeneration | Neurotoxicity | Nerve Injury | Genotoxicity | Neuroinflammatory Response | Nerve Damage

Egypt
Medical College of Wisconsin
University of Oklahoma

Recruiting

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage (TheoPHyLNNe)

Acute Kidney Injury | HIE

United States
Consorcio Centro de Investigación Biomédica en...
Instituto de Salud Carlos III; European Commission

Not yet recruiting

Metoprolol in Acute Respiratory Distress Syndrome (MAIDEN) (MAIDEN)

Acute Respiratory Distress Syndrome (ARDS)

Spain
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial (COPE-AKI)

Acute Kidney Injury

United States
Zagazig University

Recruiting

Magnesium Sulphate Neuroprotective Strategies for Preterm Deliveries

Cerebral Palsy | Premature Birth | Neonatal Death | NEUROPROTECTION | MAGNESIUM SULPHATE

Egypt
Marmara University

Recruiting

Validity and Reliability of Specific Test of Early Infant Motor Performance (STEP) Version 3.0

Cerebral Palsy | Infant, Premature, Diseases | Preterm Birth Complication

Turkey
University Hospital Hradec Kralove

Recruiting

Endothelial Glycocalyx Damage in Brain Death Organ Donors

Organ Transplant Failure or Rejection | Brain Damage Due to Hypoxia | Organ Donors

Czechia
University of Washington
National Institute on Aging (NIA)

Recruiting

Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers (PICSI-M)

Liver Cirrhosis | Quality of Life | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Peripheral Vascular Diseases | Dementia | Kidney Failure, Chronic | Chronic Disease | Lung Diseases, Interstitial | Health Communication | Lung Neoplasm | Heart Failure，Congestive | Patient Care | Health Care Quality... and other conditions

United States
University of Washington
Seattle Children's Hospital

Recruiting

Spinal Stimulation and Mobility Devices

Stroke | Cerebral Palsy | Premature Birth | Hypoxic-Ischemic Encephalopathy | Periventricular Leukomalacia

United States
King's College London
King's College Hospital NHS Trust; British Heart Foundation

Recruiting

Endothelial Glycocalyx Damage in Acute Kidney Injury

Coronary Artery Disease | Acute Kidney Injury

United Kingdom
Instituto Ecuatoriano del Corazón

Recruiting

Cumulative Blood Pressure Load and Left Ventricular Mass

Arterial Hypertension

Ecuador
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Efficacy and Safety of Docetaxel Combined With Platinum for Metastatic Hormone-sensitive Prostate Cancer

Chemotherapy Effect | DNA Damage Repair Deficiency | Chemotherapeutic Toxicity | Hormone Sensitive Metastatic Prostate Cancer

China
Shanghai 10th People's Hospital

Not yet recruiting

Assessment and Digital-health Based Intervention on Subclinical Organ Damage and Cardiovascular Risk in Chinese

Cardiovascular Diseases | Cardiovascular Morbidity | Digital Health | Subclinical Organ Damage

China
Hadassah Medical Organization

Recruiting

CMV IGG Antibodies in Semen as a Predictor for Blood Testis Barrier Damage

Male Infertility

Israel
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Mortality in Sickle Cell | Sickle Cell Cardiopulmonary Complications | Sickle Cell Organ Damage | Sickle Cell Life Expectancy and Risk Factors for Early Death | Sickle Cell Lung Disease and Sudden Death

United States
Ricard Marcos
Hospital Universitario Virgen de la Arrixaca; Instituto Murciano de Investigación...

Recruiting

Biomonitoring of Internal Exposure to MNPLs, and Its Effects, in Blood of Patients With Chronic Kidney Disease (CKD)

Chronic Kidney Diseases | Microplastics | Nanoplastics | Genotoxic Damage

Spain
Gorm Greisen

Recruiting

SafeBoosC III Two-year Follow-up

Brain Damage | Extreme Prematurity | Deficits, Neurologic

Denmark
Ain Shams University
Science,Technology & Innovation Funding Authority

Recruiting

Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers

Acute Kidney Injury | Renal Calculi | Percutaneous Nephrolithotomy | Extracorporeal Shockwave Lithotripsy

Egypt
Sohag University

Not yet recruiting

IL17 in Systemic Lupus Erythematosus Patients: Association With Disease Activity and Organ Damage

Systemic Lupus Erythematosus

Egypt
GlaxoSmithKline

Recruiting

Study to Assess Demographic, Pharmacologic, Biomarker, Clinical Features and Quality of Life (QoL) of Participants With Lupus Nephritis

Systemic Lupus Erythematosus

United Arab Emirates
All Natural Medicine Clinic, LLC

Recruiting

Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2 (sequelae)

Depression | Anxiety Disorders | Hepatitis | Insomnia | Gastro Esophageal Reflux | GERD | Glomerulonephritis | Depression, Anxiety | Depression, Bipolar | Sequelae of; Infection | Post Infection Glomerulonephritis | Post-Infectious Peripheral Neuralgia | Post-Infectious Disorder (Disorder) | Post-Infectious Arthritis and other conditions

United States
Toray Industries, Inc

Recruiting

Pilot Clinical Study of NOA-001 for ARDS (Acute Respiratory Distress Syndrome)

Acute Respiratory Distress Syndrome

Japan
Fundación IVI

Recruiting

Comparison of ICSI Outcomes in Cycles Using Testicular and Ejaculate Sperm From Couples With High SDF

DNA Damage | IVF | Oligospermia | ICSI | Embryo

Spain
Wake Forest University Health Sciences
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) (PHRASE)

Kidney Diseases | Hypertension | Pediatric Obesity | Proteinuria | Albuminuria | Kidney Injury | Blood Pressure Disorders | Autonomic Dysfunction | Pediatric Kidney Disease | Left Ventricular Dysfunction | Left Ventricular Hypertrophy | Kidney Dysfunction | Autonomic Imbalance | Left Ventricular Diastolic Dysfunction and other conditions

United States
University Hospital, Basel, Switzerland

Recruiting

Basel Postpartum Hypertension Cohort (Basel-PPHT)

Postpartum Hypertension (PPHT)

Switzerland
R.J.H. Custers
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Comparing Clinical Outcomes of the One-step Cartilage Transplantation in Cartilage Defects of the Knee With Conservative Treatment (IMPACT2)

Cartilage Damage

Netherlands
University of Turin, Italy

Recruiting

Prospective Study on Primary Aldosteronism in Resistant Hypertension (PrePARe)

Atrial Fibrillation | Primary Aldosteronism | Resistant Hypertension | Refractory Hypertension | Hypertensive End-Organ Damage | Aortic Ectasia

Italy
Regionshospitalet Viborg, Skive

Recruiting

DNA Damage and Subfertility in Males - Lifestyle Interventions to Improve Male Fertility and Health (ReproDNA)

Infertility

Denmark
Centre Hospitalier Universitaire de Nice

Recruiting

From Immune System Damage to Podocyte Cell Damage: Prospective Database and Biological Collection of Patients (Children and Adults) With MGLS and HSFP (BiobankSNI)

Nephrotic Syndrome

France
Regionshospitalet Viborg, Skive

Recruiting

DNA Damage and Subfertility in Males - Impact on ART Outcome (ReproDNA)

Infertility

Denmark
NHS Lothian

Recruiting

Using Breath, Cell Free DNA and Image Analysis to PRedIct Normal TissUe and Tumour Response During Prostate Cancer SBRT (PRINToUT)

Prostate Cancer | DNA Damage | Volatile Organic Compounds | Radiotherapy Side Effects

United Kingdom
Marc Dall'Era, MD
National Cancer Institute (NCI); Janssen, LP

Recruiting

Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Prostate Carcinoma | RAD51C Gene Mutation | BRIP1 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CDK12 Gene Mutation | CHEK1 Gene Mutation | DNA Damage Response Gene Mutation | DNA Repair Gene Mutation | FANCA Gene Mutation and other conditions

United States
University of British Columbia
University Health Network, Toronto

Recruiting

Offsetting Hippocampal Degeneration in m-sTBI (m-sTBI)

Traumatic Brain Injury | Degeneration | Memory; Loss, Mild, Following Organic Brain Damage

Canada
University of Alberta
Canadian Institutes of Health Research (CIHR)

Recruiting

Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia

Spastic Diplegia | Periventricular Leukomalacia

Canada
Wake Forest University Health Sciences
United States Department of Defense

Not yet recruiting

Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile Corpora

Urologic Diseases | Trauma Injury | Penile Diseases | Male Urogenital Diseases | Corpus Callosum Malformation | Corpora Cavernosa; Inflammation

United States
University Hospital, Strasbourg, France

Recruiting

Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma (TRAUMADORNASE)

Multiple Trauma | Respiratory Distress Syndrome, Adult

France
Alexandria University

Completed

Renal Cell Arrest and Damage Biomarkers in Progression and Outcome of Septic AKI

AKI - Acute Kidney Injury

Egypt

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