Search clinical trials for: refractory chronic cough

Total 39501 results

Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of HS-10383 in Chinese Adult Subjects With Refractory or Unexplained Chronic Cough (RUCC)

Cough
Beijing Tide Pharmaceutical Co., Ltd

Not yet recruiting

A Phase Ib/II Clinical Study in Patients With Refractory Chronic Cough

Refractory Chronic Cough
Melius Pharma AB

Not yet recruiting

Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF) (COSMIC-IPF)

Cough | Idiopathic Pulmonary Fibrosis

India
Trevi Therapeutics

Recruiting

Refractory Chronic Cough Improvement Via NAL ER (RIVER) (RIVER)

Refractory Chronic Cough

Canada, United Kingdom
Stuart Mazzone
Melbourne Health; Merck Sharp & Dohme LLC; Monash University

Not yet recruiting

Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough

Chronic Cough

Australia
University of Montana

Recruiting

Internet-Behavioral Cough Suppression Therapy

Cough | Chronic Disease

United States
Genentech, Inc.

Recruiting

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough

Chronic Refractory Cough (CRC) With Non-atopic Asthma | CRC With Atopic Asthma | Unexplained Chronic Cough | CRC With Chronic Obstructive Pulmonary Disease | CRC With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis

United States, Australia, United Kingdom, Canada
Bellus Health Inc. - a GSK company

Recruiting

A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (CALM-1)

Refractory Chronic Cough

United States, Canada, Israel, Spain, Belgium, United Kingdom, South Africa, Argentina, Netherlands, Hungary, Colombia, Turkey, Poland, France, India
Bellus Health Inc. - a GSK company

Recruiting

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (CALM-2)

Refractory Chronic Cough

Korea, Republic of, United States, Taiwan, Australia, New Zealand, Czechia, United Kingdom, Germany, Slovakia, India
Bispebjerg Hospital
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

A Comprehensive Evaluation of the Impact of ATP on Laryngeal Symptoms, Hypersensitivity and Function (MISP COUGH)

Chronic Refractory Cough

Denmark
Kefang Lai

Not yet recruiting

ATP Level and Cough Sensitivity to ATP in Subjects With Refractory Chronic Cough

Refractory Chronic Cough
Mayo Clinic

Recruiting

Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough (MACS-2)

Interstitial Lung Disease

United States
Mayo Clinic

Recruiting

Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough (MACS-1)

Refractory Chronic Cough

United States
Shionogi

Completed

Evaluation of S-600918 in Adults With Refractory Chronic Cough

Chronic Cough

United States, United Kingdom, Japan, Ukraine, Poland, Czechia
Bayer

Completed

Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

United States
University of Montana

Completed

Cough Desensitization Therapy for Cough Hypersensitivity Syndrome

Cough

United States
Aldeyra Therapeutics, Inc.

Completed

A Clinical Trial to Evaluate the Safety and Efficacy in Subjects With Chronic Cough

Chronic Cough

United States
Guangdong Hengrui Pharmaceutical Co., Ltd

Enrolling by invitation

A Study to Assess the Efficacy and Tolerance of HRS-2261 in Subjects With Refractory Chronic Cough

Refractory Chronic Cough

China
Nocion Therapeutics

Completed

Placebo-controlled, Single and Multiple Dose Study in Healthy Volunteers and Refractory Chronic Cough Patients to Assess the Safety, Tolerability, and Pharmacokinetics of Two Formulations of NTX-1175

Refractory Chronic Cough

United States
Bayer

Completed

A Trial to Learn How a New Liquid Form of BAY1817080 is Tolerated and Taken up by the Body of Healthy Male Participants (Part A). By Labeling BAY1817080 With a Radioactive Substance (Carbon 14) Researchers Want to Learn How the Study Drug is Processed and Excreted by the Body After Dosing (Part B)

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

Netherlands
Bayer

Completed

Repeat Doses of BAY 1817080 in Healthy Males & Proof of Concept in Chronic Cough Patients

Cough

United Kingdom
Bayer

Completed

Study on the Safety of Drug BAY1817080 at Different Doses and the Way the Body Absorbs and Eliminates the Drug in Japanese Healthy Adult Male Participants

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

Japan
Bayer

Completed

Study on the Safety of BAY1817080, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug in Participants With Impaired Liver Function or Normal Liver Function

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

United States
University of Montana

Completed

Cough Desensitization Therapy: Pilot 2 (CDTPilot2)

Cough

United States
Bayer

Completed

Clinical Study to Evaluate the Efficacy and Safety of Three Different Doses of BAY1817080 Compared to Placebo in Patients With Chronic Cough (PAGANINI)

Refractory and/or Unexplained Chronic Cough

Belgium, Taiwan, Australia, Netherlands, Spain, Japan, United States, Germany, Turkey, United Kingdom, Argentina, Italy, Slovakia, Hungary, France, Canada, Czechia, Poland, Russian Federation
Stuart Mazzone
Imperial College London; Monash University; Queen's University, Belfast

Completed

Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients

Cough

Australia
Nerre Therapeutics Ltd.

Completed

A Dose-ranging Study of Orvepitant in Patients With Chronic Refractory Cough

Chronic Refractory Cough

United States, Canada, United Kingdom
Bellus Health Inc

Completed

Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (SOOTHE)

Refractory Chronic Cough

United States, Germany, Canada, Czechia, Hungary, Poland, United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study of Gefapixant (MK-7264) in Japanese Adult Participants With Refractory or Unexplained Chronic Cough (MK-7264-038)

Chronic Cough

Japan
Bellus Health Inc

Terminated

A Dose Escalation Study of BLU-5937 in Unexplained or Refractory Chronic Cough (RELIEF)

Chronic Refractory Cough

United States, United Kingdom
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough

Refractory Chronic Cough

United States, United Kingdom
University Hospital, Toulouse
MSD France

Active, not recruiting

COllaboration REsearch on Chronic Cough (COREC): a French Multicenter Database (COREC)

Refractory Chronic Cough

France
Afferent Pharmaceuticals, Inc.

Completed

Effect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity (MK-7264-015)

Refractory Chronic Cough

United Kingdom
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); American Lung Association

Completed

Pilot of Zinc Acetate to Improve Chronic Cough (ZICO)

Cough

United States
Afferent Pharmaceuticals, Inc.

Completed

A Dose Escalation Study of Gefapixant (AF-219/MK-7264) in Refractory Chronic Cough (MK-7264-010)

Refractory Chronic Cough
Afferent Pharmaceuticals, Inc.

Completed

A 12-Week Study in Participants With Refractory Chronic Cough (MK-7264-012)

Refractory Chronic Cough
Afferent Pharmaceuticals, Inc.

Completed

An 8-Week Refractory Chronic Cough Study (MK-7264-021)

Refractory Chronic Cough

United States
Merck Sharp & Dohme LLC

Completed

Study of Gefapixant (MK-7264) in Adult Japanese Participants With Unexplained or Refractory Chronic Cough (MK-7264-033)

Chronic Cough

Japan
Campus Bio-Medico University

Unknown

Prevalence and Main Features of Chronic Refractory Cough. (ASSESS-CRC)

Cough

Italy
Bayer

Completed

A Study in Healthy Volunteers Investigating How Quickly and to What Extent BAY1817080 is Taken up, Distributed, Broken Down and Eliminated From the Body, as Well as the Difference Between 2 Different Types of Tablets of BAY1817080 and the Difference Between Oral Dose and Dose in the Vein

Biological Availability

Netherlands
Attenua, Inc.

Completed

A Dose Escalation Study of Bradanicline in Refractory Chronic Cough

Chronic Cough

United States
Afferent Pharmaceuticals, Inc.

Completed

Effect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (MK-7264-014)

Refractory Chronic Cough
The First Affiliated Hospital of Guangzhou Medical...

Unknown

Indomethacin for Refractory Chronic Cough

Refractory Chronic Cough

China
Adrian Hernandez
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure (IRONOUT)

Chronic Heart Failure

United States
Patara Pharma

Completed

Treatment of Refractory Chronic Cough With PA101

Refractory Chronic Cough

Netherlands, United Kingdom
Avalo Therapeutics, Inc.

Completed

An Exploratory Study of FP01 Lozenges in Subjects With Chronic Refractory Cough

Chronic Refractory Cough

United States
Shanghai Jiao Tong University School of Medicine

Completed

Study of Sequential Perfusion of Liver Grafts to Prevent Nonanastomotic Biliary Strictures After Liver Transplantation

Liver Transplantation | Transplant Recipient

China
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive
Guangzhou Medical University
Ningbo SensCure Biotechnology Co., Ltd.

Recruiting

Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic Cough (ColdCough)

Chronic Cough

China
Hull University Teaching Hospitals NHS Trust

Recruiting

An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough

Chronic Cough

United Kingdom

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