Search clinical trials for: sick

Total 3397 results

Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (SPARKLE)

Sickle Cell Disease
Novo Nordisk A/S

Not yet recruiting

A Research Study of the Effect of Food on Etavopivat in Healthy Participants

Healthy Volunteers Sickle Cell Disease, Thalassemia

United States
University of Alberta
University of Calgary

Not yet recruiting

PAUSE: Sick Day Medication Management Mobile App Study (PAUSE)

Adverse Event | Chronic Condition
Assistance Publique - Hôpitaux de Paris
Institut Pasteur

Recruiting

Physiology and Pathologies Linked to Human Splenic Function : Direct and Ex-vivo Perfusion Explorations (SPLEENVIVO)

Splenectomy

France
University Hospital, Clermont-Ferrand
Université d'Auvergne; Effik; AUDIPOG

Not yet recruiting

Prevalence of Hyperemesis Gravidarum (PHyperEG1)

Nausea and Vomiting
Instituto Nacional de Investigacao em Saude, Angola
FUNDAÇAO CALOUSTE GULBENKIAN; FUNDACIÓN BANCARIA CAIXA D'ESTALVIS I PENSIONS... and other collaborators

Recruiting

LEARNER- Low dosE AspiRiN prEterm tRial (Angola) (LEARNER)

Pregnancy Complications | Pregnancy Related | Sickle Cell Disease | Pre-Eclampsia

Angola
Region Västmanland
Karolinska Institutet; Uppsala University; Uppsala County Council, Sweden; University... and other collaborators

Not yet recruiting

A Tool for Integration of Work Environment and Patient Safety Management at Work (SIOHPS)

Stress | Occupational Health | Quality Of Care | Cost-effectiveness | Patient Safety | Sick Leave | Preventable Adverse Events | Worker Health | Safety Culture | Productivity Loss
Essen Biotech

Not yet recruiting

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease (BAH243)

Sickle Cell Disease | Sickle-Cell Disease With Crisis

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy (RAVOS)

Sickle Cell Disease | Sickle Cell SC Disease | Sickle Cell-SS Disease | Sickle Cell Retinopathy

Netherlands
Université du Québec a Montréal
Centre hospitalier de l'Université de Montréal (CHUM); Centre intégré de santé... and other collaborators

Not yet recruiting

Sustainable and Healthy Return-to-Work Program - PRATICAdr 2.0 (PRATICAdr)

Common Mental Disorder
Vanderbilt University Medical Center
Aminu Kano Teaching Hospital; Murtala Muhammed Specialist Hospital

Not yet recruiting

Prevention of Malnutrition in Children With Sickle Cell Disease (PMC-SCD)

Malnutrition | Sickle Cell Disease
State Key Laboratory of Respiratory Disease

Not yet recruiting

CO2 Supplement for Treatment of Acute Mountain Sickness

Acute Mountain Sickness | High Altitude | Inhalation; Gas

China
GRIN Therapeutics, Inc.

Recruiting

A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Tuberous Sclerosis Complex | Focal Cortical Dysplasia

Spain, United Kingdom, Australia, Belgium, Canada, Italy, Poland
The Hospital for Sick Children

Not yet recruiting

Parents Together: Supporting Parents to Promote Healthy Behaviours in Children

Parenting | Early Child Development | Child Nutrition | Child Eating Behaviours

Canada
University of Mississippi Medical Center
University of Alabama at Birmingham

Recruiting

Low Systemic/High Local Exercise Load in Peds SCD

Sickle Cell Anemia in Children

United States
RTI International

Recruiting

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease (RECIPE)

Sickle Cell Disease

United States
Daniel Morgenstern
The Hospital for Sick Children

Recruiting

Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas (VICTORY)

Low-grade Glioma

Canada
Lawson Health Research Institute
Brain Canada

Not yet recruiting

M3-JIA: Making Mindfulness Matter for Children With JIA (M3-JIA)

Children | Mental Health | Juvenile Idiopathic Arthritis | Mental Well-being

Canada
McGill University Health Centre/Research Institute...
The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Unity Health Toronto and other collaborators

Not yet recruiting

Patient Navigator Intervention for Migrant Children With Special Healthcare Needs Experiencing Care Transitions

Patient Navigation

Canada
The Hospital for Sick Children

Not yet recruiting

Isoleucine, Leucine, Valine and Tryptophan Requirements in TPN Fed Neonates

Stable Neonates Receiving Total Parenteral Nutrition (TPN)

Brazil
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain (PRESENCE)

Pain | Sickle Cell Disease
University of Plymouth

Not yet recruiting

Prediction & Mechanisms of Recovery Following IEDS

Decompression Sickness
University Health Network, Toronto
The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Emotion and Symptom-Focused Engagement (EASE) for Caregivers (EASE)

Trauma and Stressor Related Disorders | Caregiver Burden | Pediatric Cancer
St. Jude Children's Research Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

School Readiness Intervention for Preschool Children With Sickle Cell Disease

Sickle Cell Disease

United States
Gustave Roussy, Cancer Campus, Grand Paris
Medical University of Vienna; University Hospital, Essen; Fondazione IRCCS Istituto... and other collaborators

Recruiting

CARE1 Pragmatic Clinical Trial (CARE1)

Metastatic Kidney Carcinoma | Metastatic Kidney Cancer

France
Editas Medicine, Inc.

Not yet recruiting

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Sickle Cell Disease | Hemoglobinopathies | Transfusion-dependent Beta-Thalassemia
University Health Network, Toronto
The Hospital for Sick Children; Alberta Children's Hospital; British Columbia... and other collaborators

Not yet recruiting

Visual Telerehabilitation in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour (HHREHAB)

Hemianopsia

Canada
Children's National Research Institute
The Hospital for Sick Children; Ann & Robert H Lurie Children's Hospital of... and other collaborators

Recruiting

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodY (SUN-RAY)

Sickle Cell Disease

United States
Peking Union Medical College Hospital

Recruiting

Efficacy of Thyroid Hormone Replacement for Secondary Hypothyroidism Following Intracerebral Hemorrhage

Hormone Replacement Therapy | Intracerebral Hemorrhage | Low T3 Syndrome | Neurocritical Care

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Comparative Health Status and Quality of Life of Patients With Sickle Cell Disease (SCD) Who Underwent Matched-sibling Hematopoietic Stem Cell Transplantation Versus Non Transplanted SCD Case-control Patients (TRANSPLANTORN2)

Sickle Cell Disease
Nationwide Children's Hospital
Pfizer

Not yet recruiting

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | WHO Grade III Glioma | WHO Grade IV Glioma | Infant Type Hemispheric Glioma | Diffuse Midline Glioma, H3K27-altered

United States, Australia, Canada, Germany, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Effect and Process Evaluation of the SME Tool

Sick-listed Employees
European Organisation for Research and Treatment...
Novartis

Not yet recruiting

177Lu-DOTATATE for Recurrent Meningioma (LUMEN-1)

Recurrent Meningioma
The Hospital for Sick Children
Xiamen Children's Hospital

Not yet recruiting

Intestinal Perfusion After Feeding in Preterm and Term Infants

Necrotizing Enterocolitis | Premature

China
New York University

Not yet recruiting

mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria (ACCELERATE)

Sickle Cell Disease
Oman Medical Speciality Board
Armed Forces Hospital, Oman

Not yet recruiting

Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department (PASC)

Sickle-Cell Disease With Crisis
National Heart, Lung, and Blood Institute (NHLBI)
Children's National Research Institute

Recruiting

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

Sickle Cell Disease | Thalassemia | Hemoglobinopathy

United States
Bioray Laboratories
First Affiliated Hospital of Guangxi Medical University

Not yet recruiting

Clinical Study of BRL-101 in Severe SCD

Sickle Cell Disease

China
Children's Hospital Medical Center, Cincinnati
Makerere University; Ministry of Health, Uganda; Mulago Hospital, Uganda

Recruiting

Uganda Sickle Surveillance Study (US-3)

Sickle Cell Disease

Uganda
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Efficacy of Combination of Hdroxyurea and Thalidomide Over Either Hydroxyurea or Thalidomide Alone in the Treatment of Transfusion Dependent Thalassemia in Children: A Quasi-Randomised Clinical Trial

Transfusion-dependent Thalassemia

Bangladesh
Children's Hospital Medical Center, Cincinnati
Children's Hospital of Philadelphia; Emory University; Nemours Children's Health...

Not yet recruiting

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD (SC-Thrive)

Anemia, Sickle Cell
Federal State Budgetary Institution, V. A. Almazov...
National Medical Research Center for Therapy and Preventive Medicine; Tomsk... and other collaborators

Recruiting

Cardioneuroablation for Bradyarrhythmia (CARDIOBOOST)

Bradycardia | Syncope | Sick Sinus Syndrome

Russian Federation
University of Saskatchewan
The Hospital for Sick Children; University of Calgary; Children's Hospital of...

Recruiting

Canadian Bone Strength Development Study (CanBSDS)

Type-1 Diabetes

Canada
Agios Pharmaceuticals, Inc.

Not yet recruiting

A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy

Sickle Cell Disease | Nephropathy
Bioray Laboratories
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of...

Not yet recruiting

Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell Disease

Sickle Cell Disease
Bioray Laboratories
Nanfang Hospital, Southern Medical University

Not yet recruiting

Clinical Study of BRL-101 in the Treatment of Sickle Cell Disease

Sickle Cell Disease
RenJi Hospital

Not yet recruiting

Upfront Immune Checkpoint Inhibitors With Deferred Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma

Immune Checkpoint Inhibitors | Clear-cell Metastatic Renal Cell Carcinoma | Cytoreductive Nephrectomy
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

The Tryptophan Requirement in Healthy Adults

Healthy Aging
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

Heart Failure | Mitral Regurgitation

China
China National Center for Cardiovascular Diseases

Recruiting

Cardiac Denervation Ablation Strategy for Severe Sinus Bradycardia

Sinus Bradycardia

China

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