Search clinical trials for: sugammadex

Total 286 results

National Cancer Institute, Egypt

Unknown

Different Reversal Agents in Pediatric Day-case Cancer Surgery

Post-operative Residual Curarization
Augusta University

Unknown

Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans (Avapro3)

Hypertension | Obesity | Stress, Psychological | Blood Pressure

United States
Virtua Health, Inc.
Merck Sharp & Dohme LLC

Terminated

A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery

Postoperative Nausea and Vomiting | Respiratory Conditions Due to Other External Agents

United States
Brno University Hospital
KDCHOT FN Brno

Completed

Depth of Neuromuscular Blockade and the Perioperative Conditions in Laparoscopic Surgery in Pediatric Population (PedLapBlock)

Neuromuscular Blockade

Czechia
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017)

Anesthesia, General
University of South Florida
Merck Sharp & Dohme LLC

Completed

Study to Determine if Administration of Sugammadex Impacts Hospital Efficiency

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Comparison of Recovery From Rocuronium 1.2 mg/kg Followed by Sugammadex (Org 25969) 16 mg/kg at 3 Minutes With Recovery From Succinylcholine 1.0 mg/kg (19.4.303)(P05946)(MK-8616-026)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Incidence of Hypersensitivity After Administration of Sugammadex in Healthy Participants (MK-8616-101)

Hypersensitivity | Anaphylaxis
Merck Sharp & Dohme LLC

Completed

Comparison of the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616; Org 25969) in Elderly Participants With Adult Participants (MK-8616-029)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

Efficacy, Safety and Pharmacokinetics of Sugammadex (Org 25969; MK-8616) at 3 Different Time Points After 0.6 mg/kg Esmeron® in Male Participants (P05940; MK-8616-020).

Neuromuscular Blockade
The Catholic University of Korea

Unknown

Neuromuscular Blockade for Optimising Surgical Conditions During Spinal Surgery

Muscle Weakness | Neuromuscular Block | Orthopedic Disorder of Spine

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Japanese Participants. Part A (P05957)

Anesthesia, General
Seoul National University Bundang Hospital

Completed

The Effect of Deep Neuromuscular Block on Surgical Condition During Laparoscopic Colorectal Surgery (DEEPCOL)

Neuromuscular Blockade
Algemeen Ziekenhuis Maria Middelares

Withdrawn

Effect of NMBA on Surgical Conditions in THR

Postoperative Pain | Surgery

Belgium
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Caucasian Participants. Part B (P05974)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex (Org 25969) With Neostigmine as Reversal Agents for Rocuronium or Vecuronium at Reappearance of T2 (P05960)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part A: Japanese Participants (P05956)

Anesthesia, General
Erasme University Hospital

Completed

Minimal Optimal Dose of Sugammadex in Elective Surgery

Time of a TOF Ratio >0,9

Belgium
Merck Sharp & Dohme LLC

Completed

Dose-Finding Trial With Sugammadex Administered at 3 and 15 Minutes After 1.0 and 1.2 mg/kg Rocuronium Bromide in Participants of ASA Class 1-3 (P05944; MK-8616-024)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Org 25969 Administered After Zemuron® (MK-8616-042)

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Sugammadex Hypersensitivity Study (Study P06042)

Hypersensitivity
Merck Sharp & Dohme LLC

Completed

Dose-Finding Pediatric and Adult Trial With Sugammadex (Org 25969, MK-8616, SCH 900616) (19.4.306) (MK-8616-034) (P05961)

Anesthesia
Regina Elena Cancer Institute

Unknown

Recovery From Anesthesia After Robotic Assisted Radical Cystectomy

Anesthesiology Management

Italy
McMaster University

Unknown

Deep Neuromuscular Relaxation Optimizing Low-Pressure Bariatric Surgery

Bariatric Surgery
Duzce University

Completed

D Vitamin Effects on Neuromuscular Blocker Reverse Time

Vitamin D Deficiency | Neuromuscular Block | Neuromuscular Block Problem
Federal Research Institute of Pediatric Hematology...

Unknown

the Efficacy and Safety of Sugammadex in Children 0-2 Years Old

Anesthesia | Pediatric Cancer | Beta-Thalassemia | Hepatic Metastases | Pediatric Tumor | Pediatric Hepatoblastoma

Russian Federation
Attikon Hospital

Completed

Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children

Anesthesia; Functional

Greece
University Hospital, Antwerp

Completed

Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex (SUDIA)

Muscle Weakness | Muscle Fatigue | Diaphragmatic Dysfunction

Belgium
Mansoura University

Unknown

Cerebral Oxygenation and Metabolism After Reversal Of Rocuronium: Comparison Between Sugammadex Versus Neostigmine

Supratentorial Brain Tumor Surgery
Merck Sharp & Dohme LLC

Completed

A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982)

Gallbladder Disease

Germany, Italy
Seoul National University Bundang Hospital

Completed

Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery

Neuromuscular Block, Residual

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105)

Renal Insufficiency | Renal Impairment

United States
Regina Elena Cancer Institute

Completed

Quality of Awakening and Impact on Cognitive Function After Administration of Sugammadex in Robotic Radical Cystectomy

Anesthesiology Management

Italy
Lütfiye Nuri Burat Government Hospital

Unknown

Effect of IONM on Efficacy and Safety Using Sugammadex in Thyroid Surgery

Vocal Cord Paralysis | Recurrent Laryngeal Nerve

Turkey
Ankara University

Completed

Intraoperative Methylprednisolone and Sugammadex

Neuromuscular Monitoring | Sugammadex Effect

Turkey
Campus Bio-Medico University

Unknown

Role of Curarization During Anesthesia for Gynecologic Surgical Laparotomy Procedures

Curarization, Postoperative Residual

Italy
Campus Bio-Medico University

Unknown

Role of Curarization During Anesthesia for Gynecologic Surgical Laparoscopic Procedures

Curarization, Postoperative Residual

Italy
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Sildenafil Citrate Before Surgery in Improving Kidney Function in Patients With Kidney Cancer

Kidney Tumor

United States
KK Women's and Children's Hospital
Singhealth Foundation

Completed

Sugammadex Versus Neostigmine for Postoperative Nausea and Vomiting After Laparoscopic Gynaecological Surgery

Postoperative Nausea and Vomiting

Singapore
Sakarya University

Unknown

Comparison of The Severity of Agitation of Sugammadex and Atropine-Nesostigmine in Adenotonsillectomy

The Severity of Agitation in Adenotonsillectomy in Pediatric Patients

Turkey
American University of Beirut Medical Center

Completed

"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"

Anesthesia Recovery

Lebanon
The Hospital of Vestfold

Unknown

Reversal With Low Doses of Sugammadex in Patients Undergoing Non-cardiac Surgery

Postoperative Residual Curarization | Neuromuscular Block
Seoul National University Bundang Hospital
MSD Korea Ltd.

Completed

Neuromuscular Blockade During Transurethral Resection of Bladder Cancer

Neuromuscular Blockade

Korea, Republic of
Cukurova University
Private Ortopedia Hospital, Seyhan Adana

Completed

Effect of Sugammadex for Muscle Motor Response and Awareness in Intraoperative Wakeup

Spinal Curvatures

Turkey
Universidade Federal do Rio de Janeiro

Completed

Magnesium Sulfate Effect Following the Reversal of Neuromuscular Blockade Induced by Rocuronium With Sugammadex

Neuromuscular Blockade

Brazil
University Hospital Olomouc
Palacky University

Completed

Deep Neuromuscular Block During General Anaesthesia in Robotic Surgery

Observation of Neuromuscular Block | Complication of Ventilation Therapy | Postoperative Recovery

Czechia
Ain Shams University

Completed

The Effect of Sugammadex Given Based on Ideal, Actual or Adjusted Body Weight on Reversal of Rocuronium.

Muscle Relaxation

Egypt
Yonsei University

Completed

Comparison the Postoperative Quality of Recovery Between Neostigmine and Sugammadex in Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia -Randomized Controlled Trial-

Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia

Korea, Republic of

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