Rapid detection of Staphylococcus aureus in lower respiratory tract secretions from patients with suspected ventilator-associated pneumonia: evaluation of the Cepheid Xpert MRSA/SA SSTI assay
Emilia Cercenado, Mercedes Marín, Almudena Burillo, Pablo Martín-Rabadán, Marisa Rivera, Emilio Bouza, Emilia Cercenado, Mercedes Marín, Almudena Burillo, Pablo Martín-Rabadán, Marisa Rivera, Emilio Bouza
Abstract
A preclinical evaluation was conducted to evaluate the performance of the Cepheid Xpert assay on 135 lower respiratory tract secretions for detection of methicillin-resistant Staphylococcus aureus and S. aureus. Compared with the quantitative culture, the sensitivity, specificity, and positive and negative predictive values were 99.0%, 72.2%, 90.7%, and 96.3%, respectively.
Source: PubMed