Immune response to varicella vaccine in children with atopic dermatitis compared with nonatopic controls
Lynda Schneider, Adriana Weinberg, Mark Boguniewicz, Patricia Taylor, Hans Oettgen, Lisa Heughan, Daniel Zaccaro, Brian Armstrong, Aaron Holliday, Donald Y M Leung, Lynda Schneider, Adriana Weinberg, Mark Boguniewicz, Patricia Taylor, Hans Oettgen, Lisa Heughan, Daniel Zaccaro, Brian Armstrong, Aaron Holliday, Donald Y M Leung
Abstract
Atopic dermatitis subjects and controls had similar cellular immune responses to Varicella vaccine. Atopic dermatitis subjects with a history of eczema herpeticum made high levels of Varicella specific IgE.
Figures
Interferon-γ Spot Forming Cells after VZV stimulation as measured by ELISPOT in controls versus atopic dermatitis subjects
Total IgE level (A), VZV-specific IgE (B) and VZV-specific IgG (C) in control and atopic dermatitis subjects without a history of eczema herpeticum (ADEH−) and with a history of eczema herpeticum (ADEH+)
Source: PubMed