Evaluation of the psychometric properties of the PROMIS Cancer Fatigue Short Form with cancer patients
Julie M Cessna, Heather S L Jim, Steven K Sutton, Yasmin Asvat, Brent J Small, John M Salsman, Babu Zachariah, Mayer Fishman, Teresa Field, Hugo Fernandez, Lia Perez, Paul B Jacobsen, Julie M Cessna, Heather S L Jim, Steven K Sutton, Yasmin Asvat, Brent J Small, John M Salsman, Babu Zachariah, Mayer Fishman, Teresa Field, Hugo Fernandez, Lia Perez, Paul B Jacobsen
Abstract
Objective: Fatigue is common among cancer patients and adversely impacts quality of life. As such, it is important to measure fatigue accurately in a way that is not burdensome to patients. The 7-item Patient Reported Outcome Measurement Information System (PROMIS) Cancer Fatigue Short Form scale was recently developed using item response theory (IRT). The current study evaluated the psychometric properties of this scale in two samples of cancer patients using classical test theory (CTT).
Methods: Two samples were used: 121 men with prostate cancer and 136 patients scheduled to undergo hematopoietic cell transplantation (HCT) for hematologic cancer. All participants completed the PROMIS Cancer Fatigue Short Form as well as validated measures of fatigue, vitality, and depression. HCT patients also completed measures of anxiety, perceived stress, and a clinical interview designed to identify cases of cancer-related fatigue.
Results: PROMIS Cancer Fatigue Short Form items loaded on a single factor (CFI=0.948) and the scale demonstrated good internal consistency reliability in both samples (Cronbach's alphas>0.86). Correlations with psychosocial measures were significant (p values<.0001) and in the expected direction, offering evidence for convergent and concurrent validity. PROMIS Fatigue scores were significantly higher in patients who met case definition criteria for cancer-related fatigue (p<.0001), demonstrating criterion validity.
Conclusion: The current study provides evidence that the PROMIS Cancer Fatigue Short Form is a reliable and valid measure of fatigue in cancer patients.
Keywords: Cancer; Fatigue; PROMIS; Patient-reported outcomes; Psychometrics.
Conflict of interest statement
Disclosures
The authors have declared no conflicts of interest.
Copyright © 2015 Elsevier Inc. All rights reserved.
Source: PubMed