All roads lead to the ribosome
Steven Whittaker, Matthew Martin, Richard Marais, Steven Whittaker, Matthew Martin, Richard Marais
Abstract
In this issue of Cancer Cell, She et al. show that in cancer cells a protein called 4E-BP1 is a key integrator of protein synthesis downstream of the ERK and AKT signaling pathways, providing an intriguing rationale for why their simultaneous targeting could enhance therapeutic efficacy.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Source: PubMed