Alteration of gut microbiota in acute pancreatitis and associated therapeutic strategies
Ying Zhu, Qixiang Mei, Yang Fu, Yue Zeng, Ying Zhu, Qixiang Mei, Yang Fu, Yue Zeng
Abstract
Gut microbiome is considered as a crucial regulator of human health. Alteration of gut microbiome has been reported in acute pancreatitis (AP) and probably contributes to the severity of disease. Explore the precise role of gut microbiome in the pathogenesis of AP could offer new strategies to improve the clinical outcomes of AP. This review summarizes the role of gut microbiome in AP, lists possible mechanisms associated with it and offers an overview of current treatments based on gut microbiome.
Keywords: Acute pancreatitis; Bacterial translocation; Gut homeostasis; Gut microbiome; Microbiome-based treatment.
Copyright © 2021 The Authors. Published by Elsevier Masson SAS.. All rights reserved.
Source: PubMed