The suprachoroidal space: from potential space to a space with potential

Elad Moisseiev, Anat Loewenstein, Glenn Yiu, Elad Moisseiev, Anat Loewenstein, Glenn Yiu

Abstract

Recent advances have made it possible to image the suprachoroidal space, and the understanding of its clinical applications is currently being greatly expanded. This opinion piece covers the advances in imaging techniques that enable the demonstration of the suprachoroidal space, and its implication in various retinal pathologies. It also reviews its potential uses as a route for drug delivery for the treatment of retinal diseases, and its use in innovative surgical techniques. Current research is leading the way for the suprachoroidal space to be an aspect of retinal disease diagnosis, monitoring, medical treatment, and surgical manipulation.

Keywords: drug delivery; enhanced depth imaging; potential space; suprachoroidal space.

Figures

Figure 1
Figure 1
Imaging of the suprachoroidal space. Notes: (A) An EDI-OCT scan of a healthy 67-year-old patient. The suprachoroidal space can be seen as a hyporeflective band between the outer border of the choroid (white arrow) and the inner border of the sclera (black arrow), which can be followed throughout the scan. (B) An EDI-OCT scan of a patient with age-related macular degeneration in which the suprachoroidal space can be seen. Abbreviation: EDI-OCT, enhanced depth imaging-optical coherence tomography.

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Source: PubMed

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