Anaesthetic injection versus ischemic compression for the pain relief of abdominal wall trigger points in women with chronic pelvic pain

Mary L L S Montenegro, Carolina A Braz, Julio C Rosa-e-Silva, Francisco J Candido-dos-Reis, Antonio A Nogueira, Omero B Poli-Neto, Mary L L S Montenegro, Carolina A Braz, Julio C Rosa-e-Silva, Francisco J Candido-dos-Reis, Antonio A Nogueira, Omero B Poli-Neto

Abstract

Background: Chronic pelvic pain is a common condition among women, and 10 to 30 % of causes originate from the abdominal wall, and are associated with trigger points. Although little is known about their pathophysiology, variable methods have been practiced clinically. The purpose of this study was to evaluate the efficacy of local anaesthetic injections versus ischemic compression via physical therapy for pain relief of abdominal wall trigger points in women with chronic pelvic pain.

Methods: We conducted a parallel group randomized trial including 30 women with chronic pelvic pain with abdominal wall trigger points. Subjects were randomly assigned to one of two intervention groups. One group received an injection of 2 mL 0.5 % lidocaine without a vasoconstrictor into a trigger point. In the other group, ischemic compression via physical therapy was administered at the trigger points three times, with each session lasting for 60 s, and a rest period of 30 s between applications. Both treatments were administered during one weekly session for four weeks. Our primary outcomes were satisfactory clinical response rates and percentages of pain relief. Our secondary outcomes are pain threshold and tolerance at the trigger points. All subjects were evaluated at baseline and 1, 4, and 12 weeks after the interventions. The study was conducted at a tertiary hospital that was associated with a university providing assistance predominantly to working class women who were treated by the public health system.

Results: Clinical response rates and pain relief were significantly better at 1, 4, and 12 weeks for those receiving local anaesthetic injections than ischemic compression via physical therapy. The pain relief of women treated with local anaesthetic injections progressively improved at 1, 4, and 12 weeks after intervention. In contrast, women treated with ischemic compression did not show considerable changes in pain relief after intervention. In the local anaesthetic injection group, pain threshold and tolerance improved with time in the absence of significant differences between groups.

Conclusion: Lidocaine injection seems to be better for reducing the severity of chronic pelvic pain secondary to abdominal wall trigger points compared to ischemic compression via physical therapy.

Trial registration: ClinicalTrials.gov NCT00628355. Date of registration: February 25, 2008.

Figures

Fig. 1
Fig. 1
Flowchart of the study
Fig. 2
Fig. 2
Location of the trigger points. Notes: # umbilical scar; * abdominal rectus edge; dark gray: trigger points from the group 1; soft gray: trigger points from the group 2

References

    1. Latthe P, Latthe M, Say L, Gulmezoglu M, Khan KS. WHO systematic review of prevalence of chronic pelvic pain: a neglected reproductive health morbidity. BMC Public Health. 2006;6:177. doi: 10.1186/1471-2458-6-177.
    1. Romao AP, Gorayeb R, Romao GS, Poli-Neto OB, dos Reis FJ, Rosa-e-Silva JC, et al. High levels of anxiety and depression have a negative effect on quality of life of women with chronic pelvic pain. International Journal of Clinical Practice. 2009;63(5):707–11. doi: 10.1111/j.1742-1241.2009.02034.x.
    1. Stones RW, Selfe SA, Fransman S, Horn SA. Psychosocial and economic impact of chronic pelvic pain. Baillieres Best Pract Res Clin Obstet Gynaecol. 2000;14(3):415–31. doi: 10.1053/beog.1999.0084.
    1. ACOG ACOG Practice Bulletin No. 51. Chronic pelvic pain. Obstet Gynecol. 2004;103(3):589–605. doi: 10.1097/00006250-200403000-00045.
    1. Srinivasan R, Greenbaum DS. Chronic abdominal wall pain: a frequently overlooked problem. Practical approach to diagnosis and management. The American Journal of Gastroenterology. 2002;97(4):824–30.
    1. Simons D, Travell J, Simons L. Myofascial pain and dysfunction: the trigger point manual. Vol.1. 1st edition. Baltimore, MD: Williams and Wilkins; 1983.
    1. Tough EA, White AR, Richards S, Campbell J. Variability of criteria used to diagnose myofascial trigger point pain syndrome--evidence from a review of the literature. Clin J Pain. 2007;23(3):278–86. doi: 10.1097/AJP.0b013e31802fda7c.
    1. Simons DG, Travell JG, Simons LS, Cummings BD. Myofascial pain and dysfunction: the trigger point manual, vol. 1, 2nd edition edn. London: Lippincott Williams & Wilkins; 1999.
    1. Jarrell J, Giamberardino MA, Robert M, Nasr-Esfahani M. Bedside testing for chronic pelvic pain: discriminating visceral from somatic pain. Pain Res Treat. 2011;2011:692102.
    1. Iwama H, Akama Y. The superiority of water-diluted 0.25 % to neat 1 % lidocaine for trigger-point injections in myofascial pain syndrome: a prospective, randomized, double-blinded trial. Anesth Analg. 2000;91(2):408–9.
    1. Ling FW, Slocumb JC. Use of trigger point injections in chronic pelvic pain. Obstet Gynecol Clin North Am. 1993;20(4):809–15.
    1. Nazareno J, Ponich T, Gregor J. Long-term follow-up of trigger point injections for abdominal wall pain. Canadian journal of gastroenterology = Journal canadien de gastroenterologie. 2005;19(9):561–5. doi: 10.1155/2005/274181.
    1. Scott NA, Guo B, Barton PM, Gerwin RD. Trigger point injections for chronic non-malignant musculoskeletal pain: a systematic review. Pain Medicine (Malden, Mass) 2009;10(1):54–69. doi: 10.1111/j.1526-4637.2008.00526.x.
    1. Bedard RJ, Kim KM, Grindstaff TL, Hart JM. Increased active hamstring stiffness after exercise in women with a history of low back pain. Journal of Sport Rehabilitation. 2013;22(1):47–52. doi: 10.1123/jsr.22.1.47.
    1. Rickards LD. The effectiveness of non-invasive treatments for active myofascial trigger point pain: A systematic review of the literature. Int J Osteopathic Med. 2006;9:120–36. doi: 10.1016/j.ijosm.2006.07.007.
    1. Alvarez DJ, Rockwell PG. Trigger points: diagnosis and management. Am Fam Physician. 2002;65(4):653–60.
    1. Sola AE, Bonica JJ. Myofascial pain syndromes. In: Febiger L, editor. The management of pain. 2. Philadelphia: Bonica J. J; 1990. pp. 352–67.
    1. Graff-Radford SB, Reeves JL, Baker RL, Chiu D. Effects of transcutaneous electrical nerve stimulation on myofascial pain and trigger point sensitivity. Pain. 1989;37(1):1–5. doi: 10.1016/0304-3959(89)90146-2.
    1. Noguchi K, Gel YR, Brunner E, Konietschke F. nparLD: an R software package for the nonparametric analysis of longitudinal data in factorial experiments. Journal of Statistical Software. 2012;50(12):1–23. doi: 10.18637/jss.v050.i12.
    1. Kamanli A, Kaya A, Ardicoglu O, Ozgocmen S, Zengin FO, Bayik Y. Comparison of lidocaine injection, botulinum toxin injection, and dry needling to trigger points in myofascial pain syndrome. Rheumatol Int. 2005;25(8):604–11. doi: 10.1007/s00296-004-0485-6.
    1. Affaitati G, Fabrizio A, Savini A, Lerza R, Tafuri E, Costantini R, et al. A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: evaluation of pain and somatic pain thresholds. Clin Ther. 2009;31(4):705–20. doi: 10.1016/j.clinthera.2009.04.006.
    1. Sawynok J. Topical analgesics for neuropathic pain: preclinical exploration, clinical validation, future development. Eur J Pain. 2014;18(4):465–81. doi: 10.1002/j.1532-2149.2013.00400.x.
    1. Fozzard HA, Lee PJ, Lipkind GM. Mechanism of local anesthetic drug action on voltage-gated sodium channels. Curr Pharm Des. 2005;11(21):2671–86. doi: 10.2174/1381612054546833.
    1. Nouette-Gaulain K, Capdevila X, Rossignol R. Local anesthetic ‘in-situ’ toxicity during peripheral nerve blocks: update on mechanisms and prevention. Curr Opin Anaesthesiol. 2012;25(5):589–95. doi: 10.1097/ACO.0b013e328357b9e2.
    1. Zink W, Graf BM. Local anesthetic myotoxicity. Reg Anesth Pain Med. 2004;29(4):333–40. doi: 10.1097/00115550-200407000-00007.
    1. Horlocker TT, Wedel DJ. Local anesthetic toxicity--does product labeling reflect actual risk? Reg Anesth Pain Med. 2002;27(6):562–7. doi: 10.1097/00115550-200211000-00004.
    1. Srbely JZ, Dickey JP, Lee D, Lowerison M. Dry needle stimulation of myofascial trigger points evokes segmental anti-nociceptive effects. J Rehabil Med. 2010;42(5):463–8. doi: 10.2340/16501977-0535.
    1. Hsieh YL, Chou LW, Joe YS, Hong CZ. Spinal cord mechanism involving the remote effects of dry needling on the irritability of myofascial trigger spots in rabbit skeletal muscle. Arch Phys Med Rehabil. 2011;92(7):1098–105. doi: 10.1016/j.apmr.2010.11.018.
    1. Vulfsons S, Ratmansky M, Kalichman L. Trigger point needling: techniques and outcome. Curr Pain Headache Rep. 2012;16(5):407–12. doi: 10.1007/s11916-012-0279-6.
    1. Dommerholt J. Dry needling - peripheral and central considerations. J Man Manip Ther. 2011;19(4):223–7. doi: 10.1179/106698111X13129729552065.
    1. Moraska AF, Hickner RC, Kohrt WM, Brewer A. Changes in blood flow and cellular metabolism at a myofascial trigger point with trigger point release (ischemic compression): a proof-of-principle pilot study. Arch Phys Med Rehabil. 2013;94(1):196–200. doi: 10.1016/j.apmr.2012.08.216.
    1. Hains G, Descarreaux M, Hains F. Chronic shoulder pain of myofascial origin: a randomized clinical trial using ischemic compression therapy. J Manipulative Physiol Ther. 2010;33(5):362–9. doi: 10.1016/j.jmpt.2010.05.003.
    1. Farina S, Casarotto M, Benelle M, Tinazzi M, Fiaschi A, Goldoni M, et al. A randomized controlled study on the effect of two different treatments (FREMS AND TENS) in myofascial pain syndrome. Europa medicophysica. 2004;40(4):293–301.
    1. Khan KS, Hills R. Can we trust the results of trials that are stopped early? BJOG. 2006;113(7):766–8. doi: 10.1111/j.1471-0528.2006.00972.x.

Source: PubMed

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