Use of normal tissue complication probability models in the clinic
Lawrence B Marks, Ellen D Yorke, Andrew Jackson, Randall K Ten Haken, Louis S Constine, Avraham Eisbruch, Søren M Bentzen, Jiho Nam, Joseph O Deasy, Lawrence B Marks, Ellen D Yorke, Andrew Jackson, Randall K Ten Haken, Louis S Constine, Avraham Eisbruch, Søren M Bentzen, Jiho Nam, Joseph O Deasy
Abstract
The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review summarizes the currently available three-dimensional dose/volume/outcome data to update and refine the normal tissue dose/volume tolerance guidelines provided by the classic Emami et al. paper published in 1991. A "clinician's view" on using the QUANTEC information in a responsible manner is presented along with a description of the most commonly used normal tissue complication probability (NTCP) models. A summary of organ-specific dose/volume/outcome data, based on the QUANTEC reviews, is included.
Copyright 2010 Elsevier Inc. All rights reserved.
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Source: PubMed