Radiation dose-volume effects in the lung
Lawrence B Marks, Soren M Bentzen, Joseph O Deasy, Feng-Ming Spring Kong, Jeffrey D Bradley, Ivan S Vogelius, Issam El Naqa, Jessica L Hubbs, Joos V Lebesque, Robert D Timmerman, Mary K Martel, Andrew Jackson, Lawrence B Marks, Soren M Bentzen, Joseph O Deasy, Feng-Ming Spring Kong, Jeffrey D Bradley, Ivan S Vogelius, Issam El Naqa, Jessica L Hubbs, Joos V Lebesque, Robert D Timmerman, Mary K Martel, Andrew Jackson
Abstract
The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects.
Conflict of interest statement
Conflict of Interest: The authors report no conflicts.
Copyright 2010 Elsevier Inc. All rights reserved.
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Source: PubMed