Stakeholder Engagement In a Comparative Effectiveness/Implementation Study to Prevent Staphylococcus Aureus Infection Recurrence: CA-MRSA Project (CAMP2)

Abstract

Background: Methicillin-resistant or methicillin-sensitive Staphylococcus aureus skin and soft tissue infections pose serious clinical and public health challenges. Few protocols exist for outpatient education, decolonization and decontamination.

Objectives: This trial implemented infection prevention protocols in homes via community health workers/Promotoras.

Methods: We engaged clinicians, patient stakeholders, clinical and laboratory researchers, New York-based federally qualified health centers and community hospital emergency departments. The Clinician and Patient Stakeholder Advisory Committee (CPSAC) convened in person and remotely for shared decision-making and trial oversight.

Results: The intervention trial consented participants with skin and soft tissue infections from Methicillin-resistant Staphylococcus aureus or methicillin-sensitive Staphylococcus aureus, completed home visits, obtained surveillance cultures from index patients and household members and sampled household environmental surfaces at baseline and three months.

Lessons learned: The retention of the CPSAC during the trial demonstrated high levels of engagement.

Conclusions: CPSAC was highly effective throughout design and execution by troubleshooting recruitment and home visit challenges.

Trial registration: ClinicalTrials.gov NCT02566928.

Figures

Figure 1.. Sample handout of study flow chart. CHC, community health center; CHW/CDN, community health worker/Promotora MRSA, Methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive Staphylococcus aureus.

Figure 1.. Sample handout of study flow chart. CHC, community health center; CHW/CDN, community health worker/Promotora MRSA, Methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive Staphylococcus aureus.