Generating receptive endometrium in Asherman's syndrome

Caroline E Gargett, David L Healy, Caroline E Gargett, David L Healy

Abstract

Intrauterine administration of bone marrow stem/progenitor cells to a woman with thin endometrium refractory to estrogen stimulation regenerated her endometrium sufficiently to support a pregnancy. Or was it local endometrial damage induced by concurrent curettage that stimulated endogenous endometrial stem/progenitor cells into action? Or both?

Keywords: Adult stem cells; Asherman's syndrome; bone marrow; endometrial stem cells; endometrium; regeneration; transplant.

Conflict of interest statement

Conflict of Interest: None declared.

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Source: PubMed

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