The Beneficial Effects of Eccentric Exercise in the Management of Lateral Elbow Tendinopathy: A Systematic Review and Meta-Analysis

Seo Yeon Yoon, Yong Wook Kim, In Soo Shin, Seok Kang, Hyun Im Moon, Sang Chul Lee, Seo Yeon Yoon, Yong Wook Kim, In Soo Shin, Seok Kang, Hyun Im Moon, Sang Chul Lee

Abstract

As a first-line treatment for lateral elbow tendinopathy (LET), eccentric exercise has been suggested as a conservative treatment method. This study aimed to investigate the impact of eccentric exercise on LET with regard to pain reduction, and strength and functional improvement. The PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases were searched, and studies up to May 2021 were included if (1) randomization was used for patient allocation, (2) the study comprised patients with LET, (3) the intervention was eccentric exercise, and (4) the primary outcomes included improvement in pain intensity, muscle strength, or function. The meta-analysis comprised of six studies, totaling 429 participants. Additional eccentric exercise with underlying adjuvant therapy significantly improved the visual analog scale (VAS) scores (standardized mean difference [SMD], -0.63; 95% confidence interval [CI], -0.90--0.36) and muscle strength (SMD, 1.05; 95% CI, 0.78-1.33) compared with adjuvant therapy alone. Compared with the concentric or isotonic exercise group, the eccentric exercise group showed significantly improved VAS scores (SMD, -0.30; 95% CI, -0.58--0.02). However, no differences in muscle strength and function were observed between the two groups. Eccentric exercise can improve pain and muscle strength in patients with LET. The limited number of included studies and heterogeneous exercise parameters are important when interpreting these findings.

Keywords: eccentric exercise; function; lateral elbow tendinopathy; pain; tennis elbow.

Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
Flow chart of study search and selection methods.
Figure 2
Figure 2
Risk of bias summary.
Figure 3
Figure 3
Add-on effects of eccentric exercise with adjuvant therapy on (a) pain intensity and (b) muscles strength in lateral elbow tendinopathy.
Figure 3
Figure 3
Add-on effects of eccentric exercise with adjuvant therapy on (a) pain intensity and (b) muscles strength in lateral elbow tendinopathy.
Figure 4
Figure 4
Effects of eccentric exercise compared with those of other exercise (concentric or isotonic) on (a) pain intensity, (b) muscles strength, and (c) function in lateral elbow tendinopathy.

References

    1. Stasinopoulos D., Stasinopoulos I. Comparison of effects of eccentric training, eccentric-concentric training, and eccentric-concentric training combined with isometric contraction in the treatment of lateral elbow tendinopathy. J. Hand Ther. Off. J. Am. Soc. Hand Ther. 2017;30:13–19. doi: 10.1016/j.jht.2016.09.001.
    1. Bisset L.M., Vicenzino B. Physiotherapy management of lateral epicondylalgia. J. Physiother. 2015;61:174–181. doi: 10.1016/j.jphys.2015.07.015.
    1. Coombes B.K., Bisset L., Vicenzino B. Management of lateral elbow tendinopathy: One size does not fit all. J. Orthop. Sports Phys. Ther. 2015;45:938–949. doi: 10.2519/jospt.2015.5841.
    1. Kraushaar B.S., Nirschl R.P. Tendinosis of the elbow (tennis elbow). Clinical features and findings of histological, immunohistochemical, and electron microscopy studies. J. Bone Jt. Surg. Am. Vol. 1999;81:259–278. doi: 10.2106/00004623-199902000-00014.
    1. Waugh E.J., Jaglal S.B., Davis A.M., Tomlinson G., Verrier M.C. Factors associated with prognosis of lateral epicondylitis after 8 weeks of physical therapy. Arch. Phys. Med. Rehabil. 2004;85:308–318. doi: 10.1016/S0003-9993(03)00480-5.
    1. Ritz B.R. Humeral epicondylitis among gas- and waterworks employees. Scand. J. Work Environ. Health. 1995;21:478–486. doi: 10.5271/sjweh.64.
    1. Babaei-Ghazani A., Shahrami B., Fallah E., Ahadi T., Forough B., Ebadi S. Continuous shortwave diathermy with exercise reduces pain and improves function in lateral epicondylitis more than sham diathermy: A randomized controlled trial. J. Bodyw. Mov. Ther. 2020;24:69–76. doi: 10.1016/j.jbmt.2019.05.025.
    1. Ackermann P.W., Renstrom P. Tendinopathy in sport. Sports Health. 2012;4:193–201. doi: 10.1177/1941738112440957.
    1. Murtaugh B., Ihm J.M. Eccentric training for the treatment of tendinopathies. Curr. Sports Med. Rep. 2013;12:175–182. doi: 10.1249/JSR.0b013e3182933761.
    1. Kaux J.F., Forthomme B., Goff C.L., Crielaard J.M., Croisier J.L. Current opinions on tendinopathy. J. Sports Sci. Med. 2011;10:238–253.
    1. Orchard J., Kountouris A. The management of tennis elbow. Br. Med. J. (Clin. Res. Ed.) 2011;342:d2687. doi: 10.1136/bmj.d2687.
    1. Maffulli N., Longo U.G., Denaro V. Novel approaches for the management of tendinopathy. J. Bone Jt. Surg. Am. Vol. 2010;92:2604–2613. doi: 10.2106/jbjs.i.01744.
    1. O’Neill S., Watson P.J., Barry S. Why are eccentric exercises effective for Achilles’ tendinopathy? Int. J. Sports Phys. Ther. 2015;10:552–562.
    1. Alfredson H., Pietila T., Jonsson P., Lorentzon R. Heavy-load eccentric calf muscle training for the treatment of chronic Achilles tendinosis. Am. J. Sports Med. 1998;26:360–366. doi: 10.1177/03635465980260030301.
    1. Stanish W.D., Rubinovich R.M., Curwin S. Eccentric exercise in chronic tendinitis. Clin. Orthop. Relat. Res. 1986;208:65–68. doi: 10.1097/00003086-198607000-00014.
    1. Ohberg L., Alfredson H. Effects on neovascularisation behind the good results with eccentric training in chronic mid-portion Achilles tendinosis? Knee Surg. Sports Traumatol. Arthrosc. Off. J. ESSKA. 2004;12:465–470. doi: 10.1007/s00167-004-0494-8.
    1. Divani K., Chan O., Padhiar N., Twycross-Lewis R., Maffulli N., Crisp T., Morrissey D. Site of maximum neovascularisation correlates with the site of pain in recalcitrant mid-tendon Achilles tendinopathy. Man. Ther. 2010;15:463–468. doi: 10.1016/j.math.2010.03.011.
    1. van Snellenberg W., Wiley J.P., Brunet G. Achilles tendon pain intensity and level of neovascularization in athletes as determined by color Doppler ultrasound. Scand. J. Med. Sci. Sports. 2007;17:530–534. doi: 10.1111/j.1600-0838.2006.00605.x.
    1. Danielson P. Reviving the “biochemical” hypothesis for tendinopathy: New findings suggest the involvement of locally produced signal substances. Br. J. Sports Med. 2009;43:265–268. doi: 10.1136/bjsm.2008.054593.
    1. Scott A., Docking S., Vicenzino B., Alfredson H., Murphy R.J., Carr A.J., Zwerver J., Lundgreen K., Finlay O., Pollock N., et al. Sports and exercise-related tendinopathies: A review of selected topical issues by participants of the second International Scientific Tendinopathy Symposium (ISTS) Vancouver 2012. Br. J. Sports Med. 2013;47:536–544. doi: 10.1136/bjsports-2013-092329.
    1. Rees J.D., Wolman R.L., Wilson A. Eccentric exercises; why do they work, what are the problems and how can we improve them? Br. J. Sports Med. 2009;43:242–246. doi: 10.1136/bjsm.2008.052910.
    1. Rees J.D., Lichtwark G.A., Wolman R.L., Wilson A.M. The mechanism for efficacy of eccentric loading in Achilles tendon injury; an in vivo study in humans. Rheumatology. 2008;47:1493–1497. doi: 10.1093/rheumatology/ken262.
    1. Henriksen M., Aaboe J., Bliddal H., Langberg H. Biomechanical characteristics of the eccentric Achilles tendon exercise. J. Biomech. 2009;42:2702–2707. doi: 10.1016/j.jbiomech.2009.08.009.
    1. Grigg N.L., Wearing S.C., O’Toole J.M., Smeathers J.E. The effect of exercise repetition on the frequency characteristics of motor output force: Implications for Achilles tendinopathy rehabilitation. J. Sci. Med. Sport. 2014;17:13–17. doi: 10.1016/j.jsams.2013.03.014.
    1. Cullinane F.L., Boocock M.G., Trevelyan F.C. Is eccentric exercise an effective treatment for lateral epicondylitis? A systematic review. Clin. Rehabil. 2014;28:3–19. doi: 10.1177/0269215513491974.
    1. Malliaras P., Maffulli N., Garau G. Eccentric training programmes in the management of lateral elbow tendinopathy. Disabil. Rehabil. 2008;30:1590–1596. doi: 10.1080/09638280701786195.
    1. Wen D.Y., Schultz B.J., Schaal B., Graham S.T., Kim B.S. Eccentric strengthening for chronic lateral epicondylosis: A prospective randomized study. Sports Health. 2011;3:500–503. doi: 10.1177/1941738111409690.
    1. Nagrale A.V., Herd C.R., Ganvir S., Ramteke G. Cyriax physiotherapy versus phonophoresis with supervised exercise in subjects with lateral epicondylalgia: A randomized clinical trial. J. Man. Manip. Ther. 2009;17:171–178. doi: 10.1179/jmt.2009.17.3.171.
    1. Stasinopoulos D., Stasinopoulos I. Comparison of effects of Cyriax physiotherapy, a supervised exercise programme and polarized polychromatic non-coherent light (Bioptron light) for the treatment of lateral epicondylitis. Clin. Rehabil. 2006;20:12–23. doi: 10.1191/0269215506cr921oa.
    1. Higgins J. Cochrane Handbook for Systematic Reviews of Interventions. The Cochrane Collaboration; London, UK: 2011. Version 5.1. 0 [Updated March 2011]
    1. Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred Reporting Items for Systematic Reviews ansd Meta-Analyses: The PRISMA statement. Br. Med. J. (Clin. Res. Ed.) 2009;339:b2535. doi: 10.1136/bmj.b2535.
    1. Wan X., Wang W., Liu J., Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med. Res. Methodol. 2014;14:135. doi: 10.1186/1471-2288-14-135.
    1. Lipsey M.W., Wilson D.B. Practical Meta-Analysis. SAGE Publications, Inc.; Thousand Oaks, CA, USA: 2001.
    1. Borenstein M., Hedges L.V., Higgins J.P., Rothstein H.R. Introduction to Meta-Analysis. John Wiley & Sons; Hoboken, NJ, USA: 2011.
    1. Huedo-Medina T.B., Sanchez-Meca J., Marin-Martinez F., Botella J. Assessing heterogeneity in meta-analysis: Q statistic or I2 index? Psychol. Methods. 2006;11:193–206. doi: 10.1037/1082-989X.11.2.193.
    1. Anitha A., Prachi G. Effectiveness of eccentric strengthening of wrist extensors along with conventional therapy in patients with lateral epicondylitis. Res. J. Pharm. Technol. 2018;11:5340. doi: 10.5958/0974-360X.2018.00972.1.
    1. Croisier J.L., Foidart-Dessalle M., Tinant F., Crielaard J.M., Forthomme B. An isokinetic eccentric programme for the management of chronic lateral epicondylar tendinopathy. Br. J. Sports Med. 2007;41:269–275. doi: 10.1136/bjsm.2006.033324.
    1. Martinez-Silvestrini J.A., Newcomer K.L., Gay R.E., Schaefer M.P., Kortebein P., Arendt K.W. Chronic lateral epicondylitis: Comparative effectiveness of a home exercise program including stretching alone versus stretching supplemented with eccentric or concentric strengthening. J. Hand Ther. Off. J. Am. Soc. Hand Ther. 2005;18:411–419. doi: 10.1197/j.jht.2005.07.007.
    1. Peterson M., Butler S., Eriksson M., Svardsudd K. A randomized controlled trial of eccentric vs. concentric graded exercise in chronic tennis elbow (lateral elbow tendinopathy) Clin. Rehabil. 2014;28:862–872. doi: 10.1177/0269215514527595.
    1. Soderberg J., Grooten W.J., Ang B.O. Effects of eccentric training on hand strength in subjects with lateral epicondylalgia: A randomized-controlled trial. Scand. J. Med. Sci. Sports. 2012;22:797–803. doi: 10.1111/j.1600-0838.2011.01317.x.
    1. Tyler T.F., Thomas G.C., Nicholas S.J., McHugh M.P. Addition of isolated wrist extensor eccentric exercise to standard treatment for chronic lateral epicondylosis: A prospective randomized trial. J. Shoulder Elb. Surg. 2010;19:917–922. doi: 10.1016/j.jse.2010.04.041.
    1. Mafi N., Lorentzon R., Alfredson H. Superior short-term results with eccentric calf muscle training compared to concentric training in a randomized prospective multicenter study on patients with chronic Achilles tendinosis. Knee Surg. Sports Traumatol. Arthrosc. Off. J. ESSKA. 2001;9:42–47. doi: 10.1007/s001670000148.
    1. Holmgren T., Bjornsson Hallgren H., Oberg B., Adolfsson L., Johansson K. Effect of specific exercise strategy on need for surgery in patients with subacromial impingement syndrome: Randomised controlled study. Br. Med. J. (Clin. Res. Ed.) 2012;344:e787. doi: 10.1136/bmj.e787.

Source: PubMed

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