Micronized, Microencapsulated Ferric Iron Supplementation in the Form of >Your Aida Zečkanović  1 , Marko Kavčič  1 , Tomaž Prelog  1 , Alenka Šmid  2 , Janez Jazbec  1 Affiliations Expand Affiliations 1 Department of Pediatric Hematology and Oncology, University Children's Hospital, University Medical Centre Ljubljana, Bohoričeva ulica 20, 1000 Ljubljana, Slovenia. 2 The Chair of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia. PMID: 33810451 PMCID: PMC8066233 DOI: 10.3390/nu13041087 Free PMC article Item in Clipboard

Aida Zečkanović, Marko Kavčič, Tomaž Prelog, Alenka Šmid, Janez Jazbec, Aida Zečkanović, Marko Kavčič, Tomaž Prelog, Alenka Šmid, Janez Jazbec

Abstract

A major problem of oral iron supplementation efficacy in children is its tolerability and compliance. We aimed to determine the safety and efficacy of a novel food supplement >Your< Iron Syrup in the replenishment of iron stores and improvement of hematological parameters in iron-deficient children aged nine months to six years. We randomized 94 healthy children with iron deficiency in a ratio of 3:1 to either receive >Your< Iron Syrup or placebo. A 12-week supplementation with >Your< Iron Syrup resulted in a significant increase in ferritin and hemoglobin levels as compared to placebo (p = 0.04 and p = 0.02). Adverse events were reported with similar frequencies across both study arms. >Your< Iron Syrup represents an effective, well-tolerated, and safe option for the management of nutritional iron deficiency in children.

Keywords: children; food supplement; iron deficiency; liquid; microencapsulated iron; pediatric; supplementation; syrup.

Conflict of interest statement

The authors declare no conflict of interest. PharmaLinea Ltd. is involved in the marketing and sales of >Your< Iron Syrup; therefore, it has a commercial interest in this publication. PharmaLinea Ltd. and all authors declare that the data in this publication is a true and faithful representation of the performed work.

Figures

Figure 1
Figure 1
Flow diagram of the participant’s progress through the study.

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Source: PubMed

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