Characteristics and outcomes of patients undergoing anesthesia while SARS-CoV-2 infected or suspected: a multicenter register of consecutive patients

Arthur James, Audrey De Jong, Thomas Jeanmougin, Antonia Blanie, Samy Figueiredo, Pierre Goffin, Morgan Le Guen, Elie Kantor, Flora Cipriani, Sébastien Campion, Mathieu Raux, Samir Jaber, Emmanuel Futier, Jean-Michel Constantin, Société Française d’Anesthésie Réanimation (SFAR) Research Network, Gael De Rocquigny, Agnes Le Gouez, Valentin Lefrançois, Safia Zioui, Jules Greze, Eleni Pagoni, Floriane Puel, Carole Buisset, Raphael Cinotti, Christophe Péricard, Adrien Lemoine, Jean Luc Soubirou, Mathieu Fontaine, Arthur James, Audrey De Jong, Thomas Jeanmougin, Antonia Blanie, Samy Figueiredo, Pierre Goffin, Morgan Le Guen, Elie Kantor, Flora Cipriani, Sébastien Campion, Mathieu Raux, Samir Jaber, Emmanuel Futier, Jean-Michel Constantin, Société Française d’Anesthésie Réanimation (SFAR) Research Network, Gael De Rocquigny, Agnes Le Gouez, Valentin Lefrançois, Safia Zioui, Jules Greze, Eleni Pagoni, Floriane Puel, Carole Buisset, Raphael Cinotti, Christophe Péricard, Adrien Lemoine, Jean Luc Soubirou, Mathieu Fontaine

Abstract

Background: There are limited data to detail the perioperative anesthetic management and the incidence of postoperative respiratory complications among patients requiring an anesthetic procedure while being SARS-CoV-2 positive or suspected.

Methods: An observational multicenter cohort study was performed including consecutive patients who were SARS-CoV-2 confirmed or suspected and who underwent scheduled and emergency anesthesia between March 17 and May 26, 2020.

Results: A total of 187 patients underwent anesthesia with SARS-CoV-2 confirmed or suspected, with ultimately 135 (72.2%) patients positive and 52 (27.8%) negative. The median SOFA score was 2 [0; 5], and the median ARISCAT score was 49 [36; 67]. The major respiratory complications rate was 48.7% (n = 91) with 40.4% (n = 21) and 51.9% (n = 70) in the SARS-CoV-2-negative and -positive groups, respectively (p = 0.21). Among both positive and negative groups, patients with a high ARISCAT risk score (> 44) had a higher risk of presenting major respiratory complications (p < 0.01 and p = 0.1, respectively).

Discussion: When comparing SARS-COV-2-positive and -negative patients, no significant difference was found regarding the rate of postoperative complications, while baseline characteristics strongly impact these outcomes. This finding suggests that patients should be scheduled for anesthetic procedures based on their overall risk of postoperative complication, and not just based on their SARS-CoV-2 status.

Keywords: Infection; Perioperative care; Respiratory complications; SARS-CoV-2; Ventilation.

Conflict of interest statement

AJ received honoraria from LFB for an educational project outside the submitted work. SJ reports receiving consulting fees from Drager, Medtroniv, Baxter, Fresenius-Xenios, and Fisher & Paykel outside the submitted work. JMC reports personal fees and nonfinancial support from Drager, GE Healthcare, Sedana Medical, Baxter, and Amomed; personal fees from Fisher and Paykel Healthcare, Orion, Philips Medical, and Fresenius Medical Care; and nonfinancial support from LFB and Bird Corporation, outside of the submitted work. EF reports personal fees from Edwards Lifesciences, Drager, General Electric Healthcare, Fresenius Kabi, Fisher and Paykel Healthcare, and Baxter, outside of the submitted work. Other authors report no conflicts of interest.

© 2022. The Author(s).

Figures

Fig. 1
Fig. 1
Risk of major respiratory complications according to the ARISCAT risk groups. ARISCAT risk groups are as follows:  44, high risk

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Source: PubMed

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