Lymph node shape in computed tomography imaging as a predictor for axillary lymph node metastasis in patients with breast cancer

Goro Kutomi, Tousei Ohmura, Fukino Satomi, Tomoko Takamaru, Hiroaki Shima, Yasuyo Suzuki, Seiko Otokozawa, Hitoshi Zembutsu, Mitsuru Mori, Koichi Hirata, Goro Kutomi, Tousei Ohmura, Fukino Satomi, Tomoko Takamaru, Hiroaki Shima, Yasuyo Suzuki, Seiko Otokozawa, Hitoshi Zembutsu, Mitsuru Mori, Koichi Hirata

Abstract

The aim of the present study was to evaluate whether preoperative computed tomography (CT) is a useful modality for the diagnosis of axillary lymph node metastasis. The axillary lymph node status was examined in patients with primary breast cancer who had undergone surgery. In total, 75 patients were analyzed with preoperative contrast CT images, following which the patients underwent an intraoperative sentinel lymph node biopsy to determine possible predictors of axillary lymph node metastasis. The lymph node shape was classified into three groups, which included fat-, clear-and obscure-types. Multivariate analysis revealed that clear-type lymph nodes in preoperative contrast CT imaging may be an independent predictor of lymph node metastasis (odds ratio, 15; P=0.003). Therefore, the results indicated that preoperative CT examination is useful to predict axillary lymph node metastasis.

Keywords: breast cancer; computed tomography; lymph node shape.

Figures

Figure 1
Figure 1
CT images showing (A) fat-, (B) clear-and (C) obscure-type axillary lymph nodes. CT, computed tomography.

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Source: PubMed

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