ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
European Association for Cardiovascular Prevention & Rehabilitation, Zeljko Reiner, Alberico L Catapano, Guy De Backer, Ian Graham, Marja-Riitta Taskinen, Olov Wiklund, Stefan Agewall, Eduardo Alegria, M John Chapman, Paul Durrington, Serap Erdine, Julian Halcox, Richard Hobbs, John Kjekshus, Pasquale Perrone Filardi, Gabriele Riccardi, Robert F Storey, David Wood, ESC Committee for Practice Guidelines (CPG) 2008-2010 and 2010-2012 Committees, Jeroen Bax, Alec Vahanian, Angelo Auricchio, Helmut Baumgartner, Claudio Ceconi, Veronica Dean, Christi Deaton, Robert Fagard, Gerasimos Filippatos, Christian Funck-Brentano, David Hasdai, Richard Hobbs, Arno Hoes, Peter Kearney, Juhani Knuuti, Philippe Kolh, Theresa McDonagh, Cyril Moulin, Don Poldermans, Bogdan A Popescu, Željko Reiner, Udo Sechtem, Per Anton Sirnes, Michal Tendera, Adam Torbicki, Panos Vardas, Petr Widimsky, Stephan Windecker, Christian Funck-Bretano, Don Poldermans, Guy Berkenboom, Jacqueline De Graaf, Olivier Descamps, Nina Gotcheva, Kathryn Griffith, Guido Francesco Guida, Sadi Gulec, Yaakov Henkin, Kurt Huber, Y Antero Kesaniemi, John Lekakis, Athanasios J Manolis, Pedro Marques-Vidal, Luis Masana, John McMurray, Miguel Mendes, Zurab Pagava, Terje Pedersen, Eva Prescott, Quitéria Rato, Giuseppe Rosano, Susan Sans, Anton Stalenhoef, Lale Tokgozoglu, Margus Viigimaa, M E Wittekoek, Jose Luis Zamorano, European Association for Cardiovascular Prevention & Rehabilitation, Zeljko Reiner, Alberico L Catapano, Guy De Backer, Ian Graham, Marja-Riitta Taskinen, Olov Wiklund, Stefan Agewall, Eduardo Alegria, M John Chapman, Paul Durrington, Serap Erdine, Julian Halcox, Richard Hobbs, John Kjekshus, Pasquale Perrone Filardi, Gabriele Riccardi, Robert F Storey, David Wood, ESC Committee for Practice Guidelines (CPG) 2008-2010 and 2010-2012 Committees, Jeroen Bax, Alec Vahanian, Angelo Auricchio, Helmut Baumgartner, Claudio Ceconi, Veronica Dean, Christi Deaton, Robert Fagard, Gerasimos Filippatos, Christian Funck-Brentano, David Hasdai, Richard Hobbs, Arno Hoes, Peter Kearney, Juhani Knuuti, Philippe Kolh, Theresa McDonagh, Cyril Moulin, Don Poldermans, Bogdan A Popescu, Željko Reiner, Udo Sechtem, Per Anton Sirnes, Michal Tendera, Adam Torbicki, Panos Vardas, Petr Widimsky, Stephan Windecker, Christian Funck-Bretano, Don Poldermans, Guy Berkenboom, Jacqueline De Graaf, Olivier Descamps, Nina Gotcheva, Kathryn Griffith, Guido Francesco Guida, Sadi Gulec, Yaakov Henkin, Kurt Huber, Y Antero Kesaniemi, John Lekakis, Athanasios J Manolis, Pedro Marques-Vidal, Luis Masana, John McMurray, Miguel Mendes, Zurab Pagava, Terje Pedersen, Eva Prescott, Quitéria Rato, Giuseppe Rosano, Susan Sans, Anton Stalenhoef, Lale Tokgozoglu, Margus Viigimaa, M E Wittekoek, Jose Luis Zamorano
Abstract
Cardiovascular disease (CVD) due to atherosclerosis of the arterial vessel wall and to thrombosis is the foremost cause of premature mortality and of disability-adjusted life years (DALYs) in Europe, and is also increasingly common in developing countries.1 In the European Union, the economic cost of CVD represents annually E192 billion1 in direct and indirect healthcare costs. The main clinical entities are coronary artery disease (CAD), ischaemic stroke, and peripheral arterial disease (PAD). The causes of these CVDs are multifactorial. Some of these factors relate to lifestyles, such as tobacco smoking, lack of physical activity, and dietary habits, and are thus modifiable. Other risk factors are also modifiable, such as elevated blood pressure, type 2 diabetes, and dyslipidaemias, or non-modifiable, such as age and male gender. These guidelines deal with the management of dyslipidaemias as an essential and integral part of CVD prevention. Prevention and treatment of dyslipidaemias should always be considered within the broader framework of CVD prevention, which is addressed in guidelines of the Joint European Societies’ Task forces on CVD prevention in clinical practice.2 – 5 The latest version of these guidelines was published in 20075; an update will become available in 2012. These Joint ESC/European Atherosclerosis Society (EAS) guidelines on the management of dyslipidaemias are complementary to the guidelines on CVD prevention in clinical practice and address not only physicians [e.g. general practitioners (GPs) and cardiologists] interested in CVD prevention, but also specialists from lipid clinics or metabolic units who are dealing with dyslipidaemias that are more difficult to classify and treat.
Source: PubMed