Change in T2* measurements of placenta and fetal organs during Braxton Hicks contractions

Esra Abaci Turk, Jeffrey N Stout, Henry A Feldman, Borjan Gagoski, Cindy Zhou, Rubii Tamen, Mary Katherine Manhard, Elfar Adalsteinsson, Drucilla J Roberts, Polina Golland, P Ellen Grant, William H Barth Jr, Esra Abaci Turk, Jeffrey N Stout, Henry A Feldman, Borjan Gagoski, Cindy Zhou, Rubii Tamen, Mary Katherine Manhard, Elfar Adalsteinsson, Drucilla J Roberts, Polina Golland, P Ellen Grant, William H Barth Jr

Abstract

Maternal-placental perfusion can be temporarily compromised by Braxton Hicks (BH) uterine contractions. Although prior studies have employed T2* changes to investigate the effect of BH contractions on placental oxygen, the effect of these contractions on the fetus has not been fully characterized. We investigated the effect of BH contractions on quantitative fetal organ T2* across gestation together with the birth information. We observed a slight but significant decrease in fetal brain and liver T2* during contractions.

Keywords: Braxton-Hicks contraction; Fetal organ T2*; Placental MRI; Placental T2*; T2* mapping.

Conflict of interest statement

Declaration of competing interest The authors have no conflict of interests to declare.

Copyright © 2022 Elsevier Ltd. All rights reserved.

Figures

Figure 1.
Figure 1.
A. The change in average T2* in the placenta (red), fetal brain (green) and fetal liver (blue), and the change in the uterine volume (black) over time for a representative subject. B. Single slice view of T2* maps in the placenta, fetal brain and liver at the selected time points during contraction (t1, t3) and no contraction (t2) periods for the same subject.

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Source: PubMed

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