Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia
Arthur A M Wilde, Zahurul A Bhuiyan, Lia Crotti, Mario Facchini, Gaetano M De Ferrari, Thomas Paul, Chiara Ferrandi, Dave R Koolbergen, Attilio Odero, Peter J Schwartz, Arthur A M Wilde, Zahurul A Bhuiyan, Lia Crotti, Mario Facchini, Gaetano M De Ferrari, Thomas Paul, Chiara Ferrandi, Dave R Koolbergen, Attilio Odero, Peter J Schwartz
Abstract
Catecholaminergic polymorphic ventricular tachycardia is a potentially lethal disease characterized by adrenergically mediated ventricular arrhythmias manifested especially in children and teenagers. Beta-blockers are the cornerstone of therapy, but some patients do not have a complete response to this therapy and receive an implantable cardioverter-defibrillator (ICD). Given the nature of catecholaminergic polymorphic ventricular tachycardia, ICD shocks may trigger new arrhythmias, leading to the administration of multiple shocks. We describe the long-term efficacy of surgical left cardiac sympathetic denervation in three young adults with catecholaminergic polymorphic ventricular tachycardia, all of whom had symptoms before the procedure and were symptom-free afterward.
Copyright 2008 Massachusetts Medical Society.
Source: PubMed