Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies

Martine T E Puts, Samar Toubasi, Melissa K Andrew, Maureen C Ashe, Jenny Ploeg, Esther Atkinson, Ana Patricia Ayala, Angelique Roy, Miriam Rodríguez Monforte, Howard Bergman, Kathy McGilton, Martine T E Puts, Samar Toubasi, Melissa K Andrew, Maureen C Ashe, Jenny Ploeg, Esther Atkinson, Ana Patricia Ayala, Angelique Roy, Miriam Rodríguez Monforte, Howard Bergman, Kathy McGilton

Abstract

Background: frailty impacts older adults' ability to recover from an acute illness, injuries and other stresses. Currently, a systematic synthesis of available interventions to prevent or reduce frailty does not exist. Therefore, we conducted a scoping review of interventions and international policies designed to prevent or reduce the level of frailty in community-dwelling older adults.

Methods and analysis: we conducted a scoping review using the framework of Arksey and O'Malley. We systematically searched articles and grey literature to identify interventions and policies that aimed to prevent or reduce the level of frailty.

Results: fourteen studies were included: 12 randomised controlled trials and 2 cohort studies (mean number of participants 260 (range 51-610)), with most research conducted in USA and Japan. The study quality was moderate to good. The interventions included physical activity; physical activity combined with nutrition; physical activity plus nutrition plus memory training; home modifications; prehabilitation (physical therapy plus exercise plus home modifications) and comprehensive geriatric assessment (CGA). Our review showed that the interventions that significantly reduced the number of frailty markers present or the prevalence of frailty included the physical activity interventions (all types and combinations), and prehabilitation. The CGA studies had mixed findings.

Conclusion: nine of the 14 studies reported that the intervention reduced the level of frailty. The results need to be interpreted with caution, as only 14 studies using 6 different definitions of frailty were retained. Future research could combine interventions targeting more frailty markers including cognitive or psychosocial well-being.

Keywords: frail elderly; interventions; nutrition; older people; physical activity; scoping review.

© The Author 2017. Published by Oxford University Press on behalf of the British Geriatrics Society.

Figures

Figure 1.
Figure 1.
PRISMA FLOW CHART of the selection of included studies in the review.

References

    1. Dent E, Kowal P, Hoogendijk EO. Frailty measurement in research and clinical practice: a review. Eur J Intern Med 2016; 31: 3–10.
    1. Turner G, Clegg A. Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report. Age Ageing 2014; 43: 744–7.
    1. Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc 2012; 60: 1487–92.
    1. Fried LP, Tangen CM, Walston J et al. . Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56: M146–56.
    1. Ng TP, Feng L, Nyunt MS et al. . Nutritional, physical, cognitive, and combination interventions and frailty reversal among older adults: a randomized controlled trial. Am J Med 2015; 128: 1225–36.
    1. Vellas B. The White Book on Frailty. IAGG 2016 Available at: URL:
    1. Puts MT, Toubasi S, Atkinson E et al. . Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a protocol for a scoping review of the literature and international policies. BMJ Open 2016; 6: e010959.
    1. Arksey H, O'Malley J. Scoping reviews: towards a methodological framework. Int J Soc Res Methodol 2005; 8: 19–32.
    1. Colquhoun HL, Levac D, O'Brien KK et al. . Scoping reviews: time for clarity in definition, methods, and reporting. J Clin Epidemiol 2014; 67: 1291–4.
    1. Daudt HM, van MC, Scott SJ. Enhancing the scoping study methodology: a large, inter-professional team's experience with Arksey and O'Malley's framework. BMC Med Res Methodol 2013; 13: 48.
    1. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009; 62: 1006–12.
    1. Souto RQ, Khanassov V, Hong QN, Bush PL, Vedel I, Pluye P. Systematic mixed studies reviews: updating results on the reliability and efficiency of the mixed methods appraisal tool. Int J Nurs Stud 2015; 52: 500–1.
    1. Cesari M, Vellas B, Hsu FC et al. . A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study. J Gerontol A Biol Sci Med Sci 2015; 70: 216–22.
    1. Binder EF, Schechtman KB, Ehsani AA et al. . Effects of exercise training on frailty in community-dwelling older adults: results of a randomized, controlled trial. J Am Geriatr Soc 2002; 50: 1921–28.
    1. Gill TM, Baker DI, Gottschalk M et al. . A prehabilitation program for physically frail community-living older persons. Arch Phys Med Rehabil 2003; 84: 394–404.
    1. Gine-Garriga M, Guerra M, Pages E, Manini TM, Jimenez R, Unnithan VB. The effect of functional circuit training on physical frailty in frail older adults: a randomized controlled trial. J Aging Phys Act 2010; 18: 401–24.
    1. Chan DC, Tsou HH, Yang RS et al. . A pilot randomized controlled trial to improve geriatric frailty. BMC Geriatr 2012; 12: 58.
    1. Kim H, Suzuki T, Kim M et al. . Effects of exercise and milk fat globule membrane (MFGM) supplementation on body composition, physical function, and hematological parameters in community-dwelling frail Japanese women: a randomized double blind, placebo-controlled, follow-up trial. PLoS One 2015; 10: e0116256.
    1. Kwon J, Yoshida Y, Yoshida H, Kim H, Suzuki T, Lee Y. Effects of a combined physical training and nutrition intervention on physical performance and health-related quality of life in prefrail older women living in the community: a randomized controlled trial. J Am Med Dir Assoc 2015; 16: 263–8.
    1. Tarazona-Santabalbina FJ, Gomez-Cabrera MC, Perez-Ros P et al. . A multicomponent exercise intervention that reverses frailty and improves cognition, emotion, and social networking in the community-dwelling frail elderly: a randomized clinical trial. J Am Med Dir Assoc 2016; 17: 426–33.
    1. Li CM, Chen CY, Li CY, Wang WD, Wu SC. The effectiveness of a comprehensive geriatric assessment intervention program for frailty in community-dwelling older people: a randomized, controlled trial. Arch Gerontol Geriatr 2010; 50 (Suppl. 1):S39–42.
    1. Cameron ID, Fairhall N, Langron C et al. . A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial. BMC Med 2013; 11: 65.
    1. Gustafsson S, Wilhelmson K, Eklund K et al. . Health-promoting interventions for persons aged 80 and older are successful in the short term—results from the randomized and three-armed elderly persons in the risk zone study. J Am Geriatr Soc 2012; 60: 447–54.
    1. Yamada M, Arai H, Sonoda T, Aoyama T. Community-based exercise program is cost-effective by preventing care and disability in Japanese frail older adults. J Am Med Dir Assoc 2012; 13: 507–11.
    1. Mitoku K, Shimanouchi S. Home modification and prevention of frailty progression in older adults: a Japanese prospective cohort study. J Gerontol Nurs 2014; 40: 40–7.
    1. Lessende MI, Iturbe GA, Cortes BJJ. The frail elderly. Detection and management in primary care (El anciano frágil. Detección y tratamiento en AP). Aten Primaria 2010; 42: 388–98.
    1. European Innovation Partnership in active and healthy ageing. Prevention and early diagnoses of frailty and functional decline, both physical and cognitive, in older people. A compilation of good practices, 1st edition Bruxelles Belgium: European Commission; .
    1. Marzetti E, Calvani R, Landi F et al. . Innovative medicines initiative: the SPRINTT project. J Frailty Aging 2015; 4: 207–8.
    1. European Commission. European scaling-up strategy in active and healthy ageing innovation. A Europe 2020 Initiative. Bruxelles Belgium: European Commission; .
    1. Behm L, Eklund K, Wilhelmson K et al. . Health promotion can postpone frailty: results from the rct elderly persons in the risk zone. Public Health Nurs 2016; 33: 303–15.

Source: PubMed

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