Laboratory markers included in the Corona Score can identify false negative results on COVID-19 RT-PCR in the emergency room

Roberto Assandri, Ciro Canetta, Giovanni Viganò, Elisabetta Buscarini, Alessandro Scartabellati, Alessandro Montanelli, Roberto Assandri, Ciro Canetta, Giovanni Viganò, Elisabetta Buscarini, Alessandro Scartabellati, Alessandro Montanelli

Abstract

After December 2019 outbreak in China, the novel Coronavirus infection (COVID-19) has very quickly overflowed worldwide. Infection causes a clinical syndrome encompassing a wide range of clinical features, from asymptomatic or oligosymptomatic course to acute respiratory distress and death. In a very recent work we preliminarily observed that several laboratory tests have been shown as characteristically altered in COVID-19. We aimed to use the Corona score, a validated point-based algorithm to predict the likelihood of COVID-19 infection in patients presenting at the Emergency rooms. This approach combines chest images-relative score and several laboratory parameters to classify emergency room patients. Corona score accuracy was satisfactory, increasing the detection of positive patients' rate.

Keywords: COVID-19; Corona score; Emergency room; RT-PCR; laboratory markers.

Conflict of interest statement

Potential conflict of interest: None declared.

Croatian Society of Medical Biochemistry and Laboratory Medicine.

References

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Source: PubMed

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