- ICH GCP
- US Clinical Trials Registry
- Klinisk forsøg NCT00439322
Post Traumatic Stress Disorder Among VA Ambulatory Care Patients
Studieoversigt
Status
Betingelser
Detaljeret beskrivelse
Background:
Posttraumatic stress disorder (PTSD) occurs in response to an extreme traumatic stressor. It is estimated that as many as 1 million VA patients who were exposed to combat may have PTSD. VA patients with PTSD recently have been designated as a �Special Emphasis� population for which health care resources are allocated at approximately 14 times those allocated to patients without such chronic, complex, and intensive health care needs (i.e., �Basic Care� groups). Despite recognition of its substantial impact upon VA resources, the extent and means by which PTSD affects health and health care use remain unclear. This study seeks to enhance understanding of both the extent and means by which PTSD affects the health and the health care use of patients in VA ambulatory care. To meet this goal, we build on an ongoing HSR&D project, the Veterans Health Study (VHS), a prospective longitudinal study of 2,425 VA ambulatory care patients.
Objectives:
Posttraumatic stress disorder (PTSD) often afflicts victims of traumatic events such as combat. Growing evidence suggests that PTSD is related to poorer health status and to increased use of health care services. However, the extent of these effects and the means by which they occur remain unclear. The goal of this study is to enhance our understanding of both the extent and means by which PTSD affects the health and the health care use of patients in VA ambulatory care. To meet this goal, we built on an HSR&D service-directed project, the Veterans Health Study (VHS), a prospective longitudinal study of 2,425 male VA ambulatory care patients.
Methods:
This project consisted of two phases. In Phase 1, we conducted clinical interviews (CAPS) assessing PTSD with 474 patients participating in the VHS at 1-year follow-up (T12). This phase validated a brief 17-item self-report PTSD screening measure (PCL-C) against a PTSD clinical interview diagnosis. We used the results of this validation study to estimate the prevalence of PTSD in VA primary care, and to propose the use of a brief measure (PRIME-MD) as a screen for PTSD in primary care. In Phase 2, we used the PCL-C to examine the impact of PTSD on health status and health care use. We tested the hypotheses that (a) PTSD has a direct effect on health status that is independent of the effects of comorbid medical conditions, depression, and alcohol use, and (b) that controlling for comorbid medical conditions, depression and alcohol use, PTSD has both a direct effect and an indirect effect (through health status) on health care utilization. These hypotheses are being tested using structural equation methods. If, as hypothesized, PTSD exerts direct and indirect effects on health services use, then both quality of care and efficiencies in health services delivery can be improved through appropriate detection, referral, and treatment of PTSD among patients in VA ambulatory care.
Status:
Completed.
Undersøgelsestype
Tilmelding (Forventet)
Kontakter og lokationer
Studiesteder
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Massachusetts
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Bedford, Massachusetts, Forenede Stater, 01730
- Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
- Barn
- Voksen
- Ældre voksen
Tager imod sunde frivillige
Køn, der er berettiget til at studere
Beskrivelse
Inclusion Criteria:
Veterans enrolled at hospitals where study is implemented.
Exclusion Criteria:
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Kohorter og interventioner
Gruppe / kohorte |
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Gruppe 1
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Samarbejdspartnere og efterforskere
Efterforskere
- Ledende efterforsker: Avron Spiro, PhD MS, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA
- Ledende efterforsker: Cheryl S Hankin, PhD, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA
- Ledende efterforsker: Cheryl S Hankin, PhD, VA Palo Alto Health Care System, Palo Alto, CA
Publikationer og nyttige links
Generelle publikationer
- Hankin CS, Skinner KM, Sullivan LM, Miller DR, Frayne S, Tripp TJ. Prevalence of depressive and alcohol abuse symptoms among women VA outpatients who report experiencing sexual assault while in the military. J Trauma Stress. 1999 Oct;12(4):601-12. doi: 10.1023/A:1024760900213.
- Chatterjee S, Rath ME, Spiro A 3rd, Eisen S, Sloan KL, Rosen AK. Gender differences in veterans health administration mental health service use: effects of age and psychiatric diagnosis. Womens Health Issues. 2009 May-Jun;19(3):176-84. doi: 10.1016/j.whi.2009.03.002. Erratum In: Womens Health Issues. 2009 Sep-Oct;19(5):352.
Datoer for undersøgelser
Studer store datoer
Studieafslutning (Faktiske)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Skøn)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Skøn)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- IIR 96-030
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Imperial College Healthcare NHS TrustImperial College LondonRekruttering
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VA Office of Research and DevelopmentSan Diego Veterans Healthcare SystemAfsluttet
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University of Wisconsin, MadisonNational Institute of Mental Health (NIMH)Afsluttet
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VA Office of Research and DevelopmentAfsluttet
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Oregon Health and Science UniversityNational Center for Advancing Translational Sciences (NCATS); Oregon Clinical...Afsluttet
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