How to do random allocation (randomization)

Jeehyoung Kim, Wonshik Shin, Jeehyoung Kim, Wonshik Shin

Abstract

Purpose: To explain the concept and procedure of random allocation as used in a randomized controlled study.

Methods: We explain the general concept of random allocation and demonstrate how to perform the procedure easily and how to report it in a paper.

Keywords: Block randomization; Random allocation; Simple randomization; Stratified randomization.

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Simple randomization sheet.
Fig. 2
Fig. 2
An example of randomization when the block size is four.
Fig. 3
Fig. 3
Block randomization when the block size is two and four. Total eight blocks in the red-dotted line are assigned at random. The left column is for allocation and the right column is for the total sample size.
Fig. 4
Fig. 4
www.randomization.com can do block randomization more easily. In this figure, the block size is 2, 4, and 6 when the total samples are 88.
Fig. 5
Fig. 5
The reality of the randomization procedure.
Fig. 6
Fig. 6
MS word can replace A and B with a specific treatment name easily.

References

    1. Bhandari M, Richards RR, Sprague S, Schemitsch EH. The quality of reporting of randomized trials in the Journal of Bone and Joint Surgery from 1988 through 2000. J Bone Joint Surg Am. 2002;84(3):388–396.
    1. Montané E, Vallano A, Vidal X, Aguilera C, Laporte JR. Reporting randomised clinical trials of analgesics after traumatic or orthopaedic surgery is inadequate: a systematic review. BMC Clin Pharmacol. 2010;10:2.

Source: PubMed

Prochains essais cliniques

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