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Prospective Evaluation of Proteinuria and Renal Function in Non-diabetic Patients With Progressive Renal Disease (PLANET II)

14 giugno 2011 aggiornato da: AstraZeneca

Randomised, Double-blind, 52-wk, Parallel-grp Multicentre, PIIb Study to Evaluate Effects of Rosuvastatin 10mg, Rosuvastatin 40mg and Atorvastatin 80mg on Urinary Protein Excretion in Hypercholesterolaemic Non-diabetic Patients With Moderate Proteinuria

The purpose of this study is to evaluate the effects of Crestor (rosuvastatin) and (Lipitor) atorvastatin on urinary protein excretion over 1 year in non-diabetes with moderate proteinuria and hypercholesterolaemia.

Panoramica dello studio

Stato

Completato

Condizioni

Intervento / Trattamento

Tipo di studio

Interventistico

Iscrizione (Effettivo)

237

Fase

  • Fase 2

Contatti e Sedi

Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.

Luoghi di studio

  • Brasile
    • PR
      • Curitiba, PR, Brasile
        • Research Site
    • SP
      • Sao Paulo, SP, Brasile
        • Research Site
  • Bulgaria
      • Blagoevgrad, Bulgaria
        • Research Site
      • Burgas, Bulgaria
        • Research Site
      • Gabrovo, Bulgaria
        • Research Site
      • Pleven, Bulgaria
        • Research Site
      • Plovdiv, Bulgaria
        • Research Site
      • Sofia, Bulgaria
        • Research Site
      • Varna, Bulgaria
        • Research Site
      • Veliko Turnovo, Bulgaria
        • Research Site
  • Canada
    • British Columbia
      • Vancouver, British Columbia, Canada
        • Research Site
    • Newfoundland and Labrador
      • St John's, Newfoundland and Labrador, Canada
        • Research Site
    • Ontario
      • Courtice, Ontario, Canada
        • Research Site
      • East York, Ontario, Canada
        • Research Site
      • Oakville, Ontario, Canada
        • Research Site
      • Oshawa, Ontario, Canada
        • Research Site
      • Richmond Hill, Ontario, Canada
        • Research Site
      • Scarborough, Ontario, Canada
        • Research Site
      • Thunder Bay, Ontario, Canada
        • Research Site
      • Toronto, Ontario, Canada
        • Research Site
    • Quebec
      • Greenfield Park, Quebec, Canada
        • Research Site
      • Montreal, Quebec, Canada
        • Research Site
  • Danimarca
      • Fredericia, Danimarca
        • Research Site
      • Herlev, Danimarca
        • Research Site
      • Holbaek, Danimarca
        • Research Site
      • Kobenhavn, Danimarca
        • Research Site
      • Roskilde, Danimarca
        • Research Site
      • Viborg, Danimarca
        • Research Site
  • Germania
      • Berlin, Germania
        • Research Site
      • Cloppenburg, Germania
        • Research Site
      • Demmin, Germania
        • Research Site
      • Dusseldorf, Germania
        • Research Site
      • Elsenfeld, Germania
        • Research Site
      • Gottingen, Germania
        • Research Site
      • Hannover, Germania
        • Research Site
      • Wurzburg, Germania
        • Research Site
  • Italia
    • BG
      • Bergamo, BG, Italia
        • Research Site
    • BO
      • Bologna, BO, Italia
        • Research Site
    • BS
      • Brescia, BS, Italia
        • Research Site
    • CT
      • Acireale, CT, Italia
        • Research Site
    • FG
      • Foggia, FG, Italia
        • Research Site
    • FI
      • Firenze, FI, Italia
        • Research Site
    • PR
      • Parma, PR, Italia
        • Research Site
    • RC
      • Reggio Calabria, RC, Italia
        • Research Site
    • SS
      • Sassari, SS, Italia
        • Research Site
    • TE
      • Teramo, TE, Italia
        • Research Site
    • TO
      • Torino, TO, Italia
        • Research Site
    • TV
      • Castelfranco Veneto, TV, Italia
        • Research Site
      • Treviso, TV, Italia
        • Research Site
    • VE
      • Mestre, VE, Italia
        • Research Site
  • Messico
      • Aguascalientes, Messico
        • Research Site
      • D.F, Messico
        • Research Site
      • Durango, Messico
        • Research Site
      • San Luis Potos�, Messico
        • Research Site
    • DF
      • Mexico, DF, Messico
        • Research Site
    • Jalisco
      • Zapopan, Jalisco, Messico
        • Research Site
    • Morelos
      • Cuernavaca, Morelos, Messico
        • Research Site
  • Romania
      • Brasov, Romania
        • Research Site
      • Bucuresti, Romania
        • Research Site
      • Constanta, Romania
        • Research Site
      • Craiova, Romania
        • Research Site
      • Iasi, Romania
        • Research Site
      • Suceava, Romania
        • Research Site
    • Cluj
      • Cluj Napoca, Cluj, Romania
        • Research Site
    • Timis
      • Timisoara, Timis, Romania
        • Research Site
  • Stati Uniti
    • Arizona
      • Avondale, Arizona, Stati Uniti
        • Research Site
      • Phoenix, Arizona, Stati Uniti
        • Research Site
    • California
      • Pasadena, California, Stati Uniti
        • Research Site
      • Riverside, California, Stati Uniti
        • Research Site
    • Florida
      • Clearwater, Florida, Stati Uniti
        • Research Site
      • Hollywood, Florida, Stati Uniti
        • Research Site
      • Jacksonville, Florida, Stati Uniti
        • Research Site
    • Georgia
      • Augusta, Georgia, Stati Uniti
        • Research Site
    • Kansas
      • Topeka, Kansas, Stati Uniti
        • Research Site
    • Maryland
      • Columbia, Maryland, Stati Uniti
        • Research Site
    • Massachusetts
      • Springfield, Massachusetts, Stati Uniti
        • Research Site
    • Michigan
      • Detroit, Michigan, Stati Uniti
        • Research Site
    • Missouri
      • Columbia, Missouri, Stati Uniti
        • Research Site
    • New York
      • Orchard Park, New York, Stati Uniti
        • Research Site
    • North Carolina
      • Winston Salem, North Carolina, Stati Uniti
        • Research Site
    • Oklahoma
      • Oklahoma City, Oklahoma, Stati Uniti
        • Research Site
    • Pennsylvania
      • Pittsburgh, Pennsylvania, Stati Uniti
        • Research Site
    • South Carolina
      • Columbia, South Carolina, Stati Uniti
        • Research Site
    • Texas
      • Houston, Texas, Stati Uniti
        • Research Site
      • San Antonio, Texas, Stati Uniti
        • Research Site
    • Virginia
      • Richmond, Virginia, Stati Uniti
        • Research Site
    • Washington
      • Gig Harbor, Washington, Stati Uniti
        • Research Site
    • Wisconsin
      • Milwaukee, Wisconsin, Stati Uniti
        • Research Site
  • Sud Africa
      • Cape Town, Sud Africa
        • Research Site
      • Durban, Sud Africa
        • Research Site
      • Pretoria, Sud Africa
        • Research Site
    • Gauteng
      • Johannesburg, Gauteng, Sud Africa
        • Research Site
    • W Cape
      • Parow, W Cape, Sud Africa
        • Research Site
  • Ungheria
      • Ajka, Ungheria
        • Research Site
      • Baja, Ungheria
        • Research Site
      • Balatonfured, Ungheria
        • Research Site
      • Budapest, Ungheria
        • Research Site
      • Debrecen, Ungheria
        • Research Site
      • Eger, Ungheria
        • Research Site
      • Gyula, Ungheria
        • Research Site
      • Gy�r, Ungheria
        • Research Site
      • Keszthely, Ungheria
        • Research Site
      • Miskolc, Ungheria
        • Research Site
      • Nyiregyhaza, Ungheria
        • Research Site
      • Szolnok, Ungheria
        • Research Site
      • Szombathely, Ungheria
        • Research Site
      • Zalaegerszeg, Ungheria
        • Research Site

Criteri di partecipazione

I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.

Criteri di ammissibilità

Età idonea allo studio

18 anni e precedenti (Adulto, Adulto più anziano)

Accetta volontari sani

No

Sessi ammissibili allo studio

Tutto

Descrizione

Inclusion Criteria:

  • greater than or equal to 18 years of age
  • Hyperlipidemia
  • Urinary protein

Exclusion Criteria:

  • Previous rosuvastatin treatment < 6 months prior to Visit 1
  • Statin intolerance
  • Severe hypertension
  • Diabetes

Piano di studio

Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.

Come è strutturato lo studio?

Dettagli di progettazione

  • Scopo principale: Trattamento
  • Assegnazione: Randomizzato
  • Modello interventistico: Assegnazione parallela
  • Mascheramento: Quadruplicare

Cosa sta misurando lo studio?

Misure di risultato primarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Urinary Protein/Creatinine Ratio at Week 52 [LOCF]
Lasso di tempo: Assessed at baseline and Week 52 (LOCF)
Urinary protein/creatinine ratio (mg/g) =urine protein concentration (mg/dL)/ urine creatinine concentration (g/dL). Outcome measure is the ratio of Week 52 [LOCF] urine protein/creatinine ratio over baseline urine protein/creatinine ratio.
Assessed at baseline and Week 52 (LOCF)

Misure di risultato secondarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Urinary Protein/Creatinine Ratio at Week 26.
Lasso di tempo: Assessed at baseline and Week 26
Urinary protein/creatinine ratio (mg/g) =urine protein concentration (mg/dL)/ urine creatinine concentration (g/dL). Outcome measure is the ratio of Week 26 urine protein/creatinine ratio over baseline urine protein/creatinine ratio.
Assessed at baseline and Week 26
Urinary Albumin/Creatinine Ratio at Week 26
Lasso di tempo: Assessed at baseline and Week 26
Urinary albumin/creatinine ratio (mg/g) =urine albumin concentration (mg/dL)/ urine creatinine concentration (g/dL). Outcome measure is the ratio of Week 26 urine albumin/creatinine ratio over baseline urine albumin/creatinine ratio.
Assessed at baseline and Week 26
Urinary Albumin/Creatinine Ratio at Week 52 [LOCF]
Lasso di tempo: Assessed at baseline and Week 52 [LOCF]
Urinary albumin/creatinine ratio (mg/g) =urine albumin concentration (mg/dL)/ urine creatinine concentration (g/dL). Outcome measure is the ratio of Week 52 [LOCF] urine albumin/creatinine ratio over baseline urine albumin/creatinine ratio.
Assessed at baseline and Week 52 [LOCF]
Change From Baseline in Estimated Glomerular Filtration Rate (eGFR) at Week 26
Lasso di tempo: Assessed at baseline and Week 26
The change from baseline in eGFR at Week 26 is the Week 26 value minus baseline value.
Assessed at baseline and Week 26
Change From Baseline in eGFR at Week 52 [LOCF]
Lasso di tempo: Assessed at baseline and Week 52 [LOCF]
The change from baseline in eGFR at Week 52 [LOCF] is the Week 52 value or last observation carried forward minus baseline value.
Assessed at baseline and Week 52 [LOCF]
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in Total Cholesterol [TC] at Week 26.
Lasso di tempo: baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in Total Cholesterol [TC] at Week 52.
Lasso di tempo: 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in Low Density Lipoprotein Cholesterol (LDL-C) at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline inUrinary Protein/Creatinine Ratio With Percent Change From Baseline in LDL-C
Lasso di tempo: 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in High Density Lipoprotein Cholesterol [HDL-C] at Week 26
Lasso di tempo: 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in HDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in Non-high Density Lipoprotein Cholesterol [nonHDL-C] at Week 26
Lasso di tempo: Baseline and 26 weeks

Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.

)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in nonHDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in Triglyceride [TG] at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in TG at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in TC/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in TC/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in LDL-C/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in LDL-C/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in nonHDL-C/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in nonHDL-C/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in Apolipoprotein A-1 [ApoA-1] at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in ApoA-1 at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in Apolipoprotein B [ApoB] at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in ApoB at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in ApoB/ApoA-1 Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Protein/Creatinine Ratio With Percent Change From Baseline in ApoB/ApoA-1 Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary protein/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in TC at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in TC at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in LDL-C at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in LDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in HDL-C at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in HDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in nonHDL-C at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in nonHDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in TG at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in TG at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in TC/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in TC/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in LDL-C/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in LDL-C/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in nonHDL-C/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in nonHDL-C/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in ApoA-1 at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in ApoA-1 at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in ApoB at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in ApoB at Week 52
Lasso di tempo: 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
52 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in ApoB/ApoA-1 Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in Urinary Albumin/Creatinine Ratio With Percent Change From Baseline in ApoB/ApoA-1 Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in urinary albumin/creatinine ratio with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in eGFR With Percent Change From Baseline in TC at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in eGFR With Percent Change From Baseline in TC at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in eGFR With Percent Change From Baseline in LDL-C at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in eGFR With Percent Change From Baseline in LDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Changes From Baseline in eGFR With Percent Change From Baseline in HDL-C at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Changes From Baseline in eGFR With Percent Change From Baseline in HDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in nonHDL-C at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in nonHDL-C at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in TG at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in TG
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in TC/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in TC/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in LDL-C/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in LDL-C/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in nonHDL-C/HDL-C Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in nonHDL-C/HDL-C Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in ApoA1 at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in ApoA1 at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in ApoB at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in ApoB at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in ApoB/ApoA-1 Ratio at Week 26
Lasso di tempo: Baseline and 26 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 26. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 26 weeks
Correlation of Change From Baseline in eGFR With Percent Change From Baseline in ApoB/ApoA-1 Ratio at Week 52
Lasso di tempo: Baseline and 52 weeks
Correlation of changes from baseline in eGFR with percent change from baseline in lipids and lipoprotein concentrations at Week 52. (Correlation values range from -1 to +1. -1 indicates a perfect negative linear relationship while a +1 indicates a perfect linear positive relationship. A value of zero indicates no relationship.)
Baseline and 52 weeks

Collaboratori e investigatori

Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.

Sponsor

AstraZeneca

Investigatori

  • Direttore dello studio: AstraZeneca Crestor Medical Science Director, MD, AstraZeneca

Pubblicazioni e link utili

La persona responsabile dell'inserimento delle informazioni sullo studio fornisce volontariamente queste pubblicazioni. Questi possono riguardare qualsiasi cosa relativa allo studio.

Pubblicazioni generali

Studiare le date dei record

Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.

Studia le date principali

Inizio studio

1 febbraio 2006

Completamento primario (Effettivo)

1 giugno 2009

Completamento dello studio (Effettivo)

1 giugno 2009

Date di iscrizione allo studio

Primo inviato

23 febbraio 2006

Primo inviato che soddisfa i criteri di controllo qualità

24 febbraio 2006

Primo Inserito (Stima)

27 febbraio 2006

Aggiornamenti dei record di studio

Ultimo aggiornamento pubblicato (Stima)

16 giugno 2011

Ultimo aggiornamento inviato che soddisfa i criteri QC

14 giugno 2011

Ultimo verificato

1 giugno 2011

Maggiori informazioni

Termini relativi a questo studio

Parole chiave

Termini MeSH pertinenti aggiuntivi

Altri numeri di identificazione dello studio

  • D3569C00011
  • PLANET II

Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .

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Condizioni

Malattie rare

Interventi farmacologici

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Sponsor / Collaboratori

Sedi

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