Risk Factors of Sternal Wound Infection After Coronary Artery Bypass Graft
調査の概要
詳細な説明
Deep sternal wound infection after coronary artery bypass graft is a very dangerous complication as it prolongs hospital stay, increase morbidity and mortality, and increase cost of care.
As a risk factor of surgical site infection, risk index reported by NNIS (national nosocomial infection surveillance), Euroscore, or Society of thoracic surgeon risk score are currently used. However, as various performances are reported regarding these index or scoring systems, and many factors are needed for these index or scoring system, there is a need to develop a more simple risk factor with better performance. We focused on the differential blood cell count, as the neutrophil and lymphocyte count are related to the degree of surgical invasion, and inflammatory response. Previous studies reported that the neutrophilia or lymphopenia is related to postoperative infection. Therefore, we are trying to evaluate the performance of preoperative or postoperative the blood cell differential count as a risk factor for sternal wound infection after coronary artery bypass surgery.
研究の種類
入学 (予想される)
連絡先と場所
研究場所
-
-
-
Seoul、大韓民国、135-710
- 募集
- Samsung Medical Center
-
副調査官：
- Sangmin M. Lee, MD, PhD
-
副調査官：
- Young Tak Lee, MD, PhD
-
-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Those underwent coronary artery bypass graft surgery with median sternotomy in Samsung Medical Center during the period of January 2008 and December 2011.
Exclusion Criteria:
- Those underwent coronary artery bypass graft surgery with mini-thoracotomy
- Those with insufficient study data recognized by electronic medical record
研究計画
研究はどのように設計されていますか？
デザインの詳細
コホートと介入
グループ/コホート |
|---|
|
Coronary Artery Bypass Graft Group
Those underwent coronary artery bypass graft surgery with median sternotomy in Samsung Medical Center during the period of January 2008 and December 2011.
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
postoperative surgical wound infection
時間枠：within first week after the end of coronary artery bypass graft surgery
|
postoperative surgical wound infection within first week after the end of coronary artery bypass graft surgery, classified as a superfical or deep sternal wound infection
|
within first week after the end of coronary artery bypass graft surgery
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
preoperative total leukocyte count
時間枠：1 day before surgery
|
preoperative total leukocyte count
|
1 day before surgery
|
|
preoperative neutrophil count
時間枠：1 day before surgery
|
preoperative neutrophil count
|
1 day before surgery
|
|
preoperative lymphocyte count
時間枠：1 day before surgery
|
preoperative lymphocyte count
|
1 day before surgery
|
|
postoperative total leukocyte count
時間枠：2 hour after the end of surgery
|
postoprative total leukocyte count
|
2 hour after the end of surgery
|
|
postoperative neutrophil count
時間枠：2 hour after the end of surgery
|
postoperative neutrophil count
|
2 hour after the end of surgery
|
|
postoperative lymphocyte count
時間枠：2 hour after the end of surgery
|
postoperative lymphocyte count
|
2 hour after the end of surgery
|
|
preoperative NNIS risk index
時間枠：1 day before surgery
|
preoperative NNIS risk index
|
1 day before surgery
|
|
preoperative EuroScore
時間枠：1 day before surgery
|
preoperative EuroScore
|
1 day before surgery
|
|
Preoperative STS
時間枠：1 day before surgery
|
Preoperative STS (Society of Thoracic Surgeons risk score)
|
1 day before surgery
|
|
the incidence of surgical reopen with surgical wound infection
時間枠：within 1 month after surgery
|
the incidence of surgical reopen with surgical wound infection
|
within 1 month after surgery
|
協力者と研究者
スポンサー
捜査官
- 主任研究者：Won Ho Kim, MD, PhD、Samsung Medical Center
研究記録日
主要日程の研究
研究開始
一次修了 (予想される)
研究の完了 (予想される)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (見積もり)
学習記録の更新
投稿された最後の更新 (見積もり)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。