Risk Factors of Sternal Wound Infection After Coronary Artery Bypass Graft
Panoramica dello studio
Stato
Descrizione dettagliata
Deep sternal wound infection after coronary artery bypass graft is a very dangerous complication as it prolongs hospital stay, increase morbidity and mortality, and increase cost of care.
As a risk factor of surgical site infection, risk index reported by NNIS (national nosocomial infection surveillance), Euroscore, or Society of thoracic surgeon risk score are currently used. However, as various performances are reported regarding these index or scoring systems, and many factors are needed for these index or scoring system, there is a need to develop a more simple risk factor with better performance. We focused on the differential blood cell count, as the neutrophil and lymphocyte count are related to the degree of surgical invasion, and inflammatory response. Previous studies reported that the neutrophilia or lymphopenia is related to postoperative infection. Therefore, we are trying to evaluate the performance of preoperative or postoperative the blood cell differential count as a risk factor for sternal wound infection after coronary artery bypass surgery.
Tipo di studio
Iscrizione (Anticipato)
Contatti e Sedi
Luoghi di studio
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Seoul, Corea, Repubblica di, 135-710
- Reclutamento
- Samsung Medical Center
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Sub-investigatore:
- Sangmin M. Lee, MD, PhD
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Sub-investigatore:
- Young Tak Lee, MD, PhD
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Criteri di partecipazione
Criteri di ammissibilità
Età idonea allo studio
Accetta volontari sani
Sessi ammissibili allo studio
Metodo di campionamento
Popolazione di studio
Descrizione
Inclusion Criteria:
- Those underwent coronary artery bypass graft surgery with median sternotomy in Samsung Medical Center during the period of January 2008 and December 2011.
Exclusion Criteria:
- Those underwent coronary artery bypass graft surgery with mini-thoracotomy
- Those with insufficient study data recognized by electronic medical record
Piano di studio
Come è strutturato lo studio?
Dettagli di progettazione
Coorti e interventi
Gruppo / Coorte |
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Coronary Artery Bypass Graft Group
Those underwent coronary artery bypass graft surgery with median sternotomy in Samsung Medical Center during the period of January 2008 and December 2011.
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Cosa sta misurando lo studio?
Misure di risultato primarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
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postoperative surgical wound infection
Lasso di tempo: within first week after the end of coronary artery bypass graft surgery
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postoperative surgical wound infection within first week after the end of coronary artery bypass graft surgery, classified as a superfical or deep sternal wound infection
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within first week after the end of coronary artery bypass graft surgery
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Misure di risultato secondarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
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preoperative total leukocyte count
Lasso di tempo: 1 day before surgery
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preoperative total leukocyte count
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1 day before surgery
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preoperative neutrophil count
Lasso di tempo: 1 day before surgery
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preoperative neutrophil count
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1 day before surgery
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preoperative lymphocyte count
Lasso di tempo: 1 day before surgery
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preoperative lymphocyte count
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1 day before surgery
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postoperative total leukocyte count
Lasso di tempo: 2 hour after the end of surgery
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postoprative total leukocyte count
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2 hour after the end of surgery
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postoperative neutrophil count
Lasso di tempo: 2 hour after the end of surgery
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postoperative neutrophil count
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2 hour after the end of surgery
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postoperative lymphocyte count
Lasso di tempo: 2 hour after the end of surgery
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postoperative lymphocyte count
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2 hour after the end of surgery
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preoperative NNIS risk index
Lasso di tempo: 1 day before surgery
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preoperative NNIS risk index
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1 day before surgery
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preoperative EuroScore
Lasso di tempo: 1 day before surgery
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preoperative EuroScore
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1 day before surgery
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Preoperative STS
Lasso di tempo: 1 day before surgery
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Preoperative STS (Society of Thoracic Surgeons risk score)
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1 day before surgery
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the incidence of surgical reopen with surgical wound infection
Lasso di tempo: within 1 month after surgery
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the incidence of surgical reopen with surgical wound infection
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within 1 month after surgery
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Collaboratori e investigatori
Sponsor
Investigatori
- Investigatore principale: Won Ho Kim, MD, PhD, Samsung Medical Center
Studiare le date dei record
Studia le date principali
Inizio studio
Completamento primario (Anticipato)
Completamento dello studio (Anticipato)
Date di iscrizione allo studio
Primo inviato
Primo inviato che soddisfa i criteri di controllo qualità
Primo Inserito (Stima)
Aggiornamenti dei record di studio
Ultimo aggiornamento pubblicato (Stima)
Ultimo aggiornamento inviato che soddisfa i criteri QC
Ultimo verificato
Maggiori informazioni
Termini relativi a questo studio
Termini MeSH pertinenti aggiuntivi
Altri numeri di identificazione dello studio
- 2012-05-067-001
Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .
Prove cliniche su Innesto di bypass dell'arteria coronaria
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I.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioReclutamentoCoronary Artery DiseaseItalia