Risk Factors of Sternal Wound Infection After Coronary Artery Bypass Graft
研究概览
详细说明
Deep sternal wound infection after coronary artery bypass graft is a very dangerous complication as it prolongs hospital stay, increase morbidity and mortality, and increase cost of care.
As a risk factor of surgical site infection, risk index reported by NNIS (national nosocomial infection surveillance), Euroscore, or Society of thoracic surgeon risk score are currently used. However, as various performances are reported regarding these index or scoring systems, and many factors are needed for these index or scoring system, there is a need to develop a more simple risk factor with better performance. We focused on the differential blood cell count, as the neutrophil and lymphocyte count are related to the degree of surgical invasion, and inflammatory response. Previous studies reported that the neutrophilia or lymphopenia is related to postoperative infection. Therefore, we are trying to evaluate the performance of preoperative or postoperative the blood cell differential count as a risk factor for sternal wound infection after coronary artery bypass surgery.
研究类型
注册 (预期的)
联系人和位置
学习地点
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Seoul、大韩民国、135-710
- 招聘中
- Samsung Medical Center
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副研究员：
- Sangmin M. Lee, MD, PhD
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副研究员：
- Young Tak Lee, MD, PhD
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Those underwent coronary artery bypass graft surgery with median sternotomy in Samsung Medical Center during the period of January 2008 and December 2011.
Exclusion Criteria:
- Those underwent coronary artery bypass graft surgery with mini-thoracotomy
- Those with insufficient study data recognized by electronic medical record
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
|---|
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Coronary Artery Bypass Graft Group
Those underwent coronary artery bypass graft surgery with median sternotomy in Samsung Medical Center during the period of January 2008 and December 2011.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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postoperative surgical wound infection
大体时间：within first week after the end of coronary artery bypass graft surgery
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postoperative surgical wound infection within first week after the end of coronary artery bypass graft surgery, classified as a superfical or deep sternal wound infection
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within first week after the end of coronary artery bypass graft surgery
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
preoperative total leukocyte count
大体时间：1 day before surgery
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preoperative total leukocyte count
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1 day before surgery
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preoperative neutrophil count
大体时间：1 day before surgery
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preoperative neutrophil count
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1 day before surgery
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preoperative lymphocyte count
大体时间：1 day before surgery
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preoperative lymphocyte count
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1 day before surgery
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postoperative total leukocyte count
大体时间：2 hour after the end of surgery
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postoprative total leukocyte count
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2 hour after the end of surgery
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postoperative neutrophil count
大体时间：2 hour after the end of surgery
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postoperative neutrophil count
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2 hour after the end of surgery
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postoperative lymphocyte count
大体时间：2 hour after the end of surgery
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postoperative lymphocyte count
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2 hour after the end of surgery
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preoperative NNIS risk index
大体时间：1 day before surgery
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preoperative NNIS risk index
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1 day before surgery
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preoperative EuroScore
大体时间：1 day before surgery
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preoperative EuroScore
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1 day before surgery
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Preoperative STS
大体时间：1 day before surgery
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Preoperative STS (Society of Thoracic Surgeons risk score)
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1 day before surgery
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the incidence of surgical reopen with surgical wound infection
大体时间：within 1 month after surgery
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the incidence of surgical reopen with surgical wound infection
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within 1 month after surgery
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合作者和调查者
调查人员
- 首席研究员：Won Ho Kim, MD, PhD、Samsung Medical Center
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
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