A Phase II Study of CPC-201 to Treat Alzheimer's Disease Type Dementia

Inclusion Criteria:

• Aged 50 - 79 years inclusive.
• Meeting the diagnosis of probable Alzheimer's Disease
• Of moderate severity (Mini-Mental Status Exam [MMSE] score 10 - 20 inclusive).
• Patients must be in generally good health as indicated by their medical history and physical examination, vital signs, electrocardiogram (ECG), and standard laboratory tests.

Exclusion Criteria:

• Women of child bearing potential.
• History or presence of a seizure disorder.
• History of peptic ulcer disease, urinary or gastric retention; asthma or obstructive pulmonary disease.
• History or presence of bladder outflow obstruction, gastrointestinal obstructive disorder or reduced GI motility, or narrow-angle glaucoma.
• History or presence of gastrointestinal, hepatic, or renal disease, or other condition known to interfere with the absorption, distribution, metabolism or excretion of drugs.
• History or presence of myasthenia.
• Known hypersensitivity to donepezil, solifenacin or related drugs.
• Any other clinically relevant acute or chronic diseases which could interfere with patients' safety during the trial, or expose them to undue risk, or which could interfere with study objectives.
• Patients who have participated in another clinical trial with an investigational drug within previous 30 days.