여성 건강 이니셔티브 강력하고 건강한 연구 (WHISH)

실험적: 신체 활동 중재

신체 활동 중재 그룹은 에어로빅, 유연성, 균형, 근력 및 앉아 있는 시간 감소를 포함하여 신체 활동에 대한 지침을 받게 됩니다. 주요 리소스는 National Institute of Aging Go4Life 운동 및 신체 활동 자료입니다. 자료는 노인을 위한 신체 활동에 대한 미국 국가 지침을 기반으로 합니다.

행동: 신체 활동

PA 개입은 에어로빅, 균형, 근력, 유연성의 복합 활동 프로그램으로 구성됩니다. 개입에는 참가자들이 하루 종일 모든 형태의 PA를 늘리고 앉아 있는 시간을 줄이도록 격려하는 것이 포함될 것입니다. 여기에는 레저 스포츠, 정원 가꾸기, 에스컬레이터 대신 계단 사용, 친구와 여유롭게 걷기, 원격 제어 장치 사용 줄이기 등의 활동이 포함될 수 있습니다. 개입은 주로 웹사이트 지원 및 사용 가능한 리소스와 함께 우편으로 수행됩니다.

간섭 없음: 일반적인 활동 제어

평소 활동

Cardiovascular Events (Composite Myocardial Infarction, Stroke, Cardiovascular Mortality

WHI centrally adjudicated events and CMS FFS-identified events. CVD defined as (first event since enrollment in WHISH of) MI, stroke, cardiovascular (CV) death.

Physical Function (Physical Function Score From Self-report, RAND-36)

Rand-36 Physical Function Scale. Score 0-100; a higher score indicates a more favorable health state in regards to physical functioning. The single value for this Outcome is based on the average of all collected measurements.

Non-Cardiovascular Disease Mortality

Safety. WHI centrally adjudicated events and CMS FFS-identified events.

Hip Fracture

Safety. WHI centrally adjudicated events and CMS FFS-identified events.

Falls / Year

Safety; self-report

Clinical (Non-hip) Fracture

Safety. Self-report

Peripheral Artery Disease

WHI centrally adjudicated events and CMS FFS-identified events.

Venous Thromboembolic Event

WHI centrally adjudicated events and CMS FFS-identified events.

Coronary Revascularization (Coronary Artery Bypass Graft or Percutaneous Coronary Intervention)

Safety; adjudicated events

Mobility Loss

Self-report of ability to climb one flight of stairs or ability to walk one block. Scored 1, 2 or 3 with 1=limited a lot, 2=limited a little, 3=not limited at all. Either stairs or walk with score of 2 or 3 is defined as being able to be mobile.

Mobility Loss: Defined as Yes if a participant self-reports being limited a lot (score =1) in both climbing one flight of stairs and walking one block.

Mobility loss defined as Yes is reported as an Event.

Short Physical Performance Battery (SPPB)

SPPB collected one time during second funding period for WHISH, within the 4-year trial period, as part of the Women's Health Initiative in-home visit, the Long Life Study 2 during 2022-2024. The Established Populations for the Epidemiologic Studies of the Eldery (EPESE) Short Physical Performance Battery (SPPB) ranges from 0 to 12, with higher scores indicating better physical performance.

Sleep Disturbance

Self-report of sleep patterns such as falling asleep, waking during the night, quality of night's sleep. Score scale: 0 - 20; a higher score indicates greater sleep disturbance. Levine DW, Kaplan RM, Kripke DF, Naughton MJ, Shumaker SA. Factor structure and measurement invariance of the Women's Health Initiative Insomnia Rating Scale. Psycho Assess. 2003 Jun; 15(2):123-36. Data not collected prior to 1/6/2021. The single value for this Outcome is based on the average of all collected measurements.

Depressive Symptoms

Shortened version of the Center for Epidemiological Studies Depression Scale (CES- D). Score (probability) for depression. Score scale: 0 - 1; a higher score indicates a greater likelihood of depression. Burman M, Wells K, Leake B, Landsverk J. Development of a brief screening instrument for detecting depressive disorders. Medical care 1988; 26: 8, 775-789. Data not collected prior to 1/6/2021. The single value for this Outcome is based on the average of all collected measurements.