금연 문제 인간 면역 결핍 바이러스 하이브리드 시험 (QMH)

a smoking cessation Digital Therapeutic (DTx) for people with HIV (PWH)

LTQ-H consists of 319 screens divided into: (a) HIV-tailored smoking cessation ACT skills, (b) education about tobacco dependence and treatment (USCPG), and (c) NRT psychoeducation and adherence. Content is gradually presented across 28 modules (14 education and 14 skills) that can be completed in 14 days.

• 흡연 중단 디지털 치료 (DTX)

an evidence-based DTx designed for the general population

This DTx, QuitGuide was adapted from the National Cancer Institute Smokefree.gov Initiative's QuitGuide's 5 modules have the following intervention components: (a) psychoeducation about the impact of smoking on health, (b) setting up a quit date and a quit plan, (c) selecting reasons for quitting, (d) tracking triggers and smoking habits, and (e) tips for quitting.

• 일반 인구를 위해 설계된 증거 기반 DTX

Abstinence is determined by a self-report of not smoking any cigarettes for greater than or equal to 7 days prior to Weeks 6, 12, 18, and 24 and biochemically verified by an expired carbon monoxide breath test or a cotinine level saliva test at Weeks 6, 12, 18, and 24. Criteria for the bioverification tests to be considered abstinent includes a reading of <6 parts per million using an iCOquit Smokerlyzer carbon monoxide breath test OR a cotinine level of 30 or less ng/ml using an iScreen saliva test.

If the participant does not meet both criteria of the self report of 7 or more days of abstinence plus a bioverification test below the thresholds listed above, they are not considered abstinent. As per convention, participants are assumed to be smoking if they report smoking at the time-point, cannot be reached to provide data at the time-point, fail to provide a breath sample at the time-point, or provide a breath sample at the time-point that is greater than or equal to 6 ppm.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 7 days prior to the timepoint.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 7 days prior to the timepoint.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 7 days prior to the timepoint.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 7 days prior to the timepoint.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 30 days but < 30 days prior to the timepoint.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 30 days prior to the timepoint.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 30 days prior to the timepoint.

Percent of subjects in each group self-reporting no smoking at all for greater or equal to 30 days prior to the timepoint.

Change in self-reported number of cigarettes smoked per day, averaged within groups.

Change in self-reported number of cigarettes smoked per day, averaged within groups.

Change in self-reported number of cigarettes smoked per day, averaged within groups.

Change in self-reported number of cigarettes smoked per day, averaged within groups.

Average number of quit attempts self-reported per group at the specified time point. Quit attempts are defined by no smoking cigarettes at all for 24 hours or more.

Average number of quit attempts self-reported per group at the specified time point. Quit attempts are defined by no smoking cigarettes at all for 24 hours or more.

Average number of quit attempts self-reported per group at the specified time point. Quit attempts are defined by no smoking cigarettes at all for 24 hours or more.

Average number of quit attempts self-reported per group at the specified time point. Quit attempts are defined by no smoking cigarettes at all for 24 hours or more.

Average self-reported scores of acceptance of cravings on the physical sensations subscale of the Avoidance and Inflexibility Scale. Scores range from 4-20 with lower scores indicating more acceptance of smoking cravings.

Average self-reported scores of acceptance of cravings on the physical sensations subscale of the Avoidance and Inflexibility Scale. Scores range from 4-20 with lower scores indicating more acceptance of smoking cravings.

Average self-reported scores of acceptance of cravings on the physical sensations subscale of the Avoidance and Inflexibility Scale. Scores range from 4-20 with lower scores indicating more acceptance of smoking cravings.

Average self-reported scores of acceptance of cravings on the physical sensations subscale of the Avoidance and Inflexibility Scale. Scores range from 4-20 with lower scores indicating more acceptance of smoking cravings.

Average frequency of app use over the 24-week study period. Measured by average number of app openings.

Average duration of app use over the 24-week study period.

Average number of app modules completed over the 24-week study period.